Dual Targeting of Matrix Metalloproteases and the MAPK Pathway in Acute Myeloid Leukemia Cells Using an MMP-activated anthrax lethal toxin (PrAgL1/LF) by Al Saneh, Ahmad

“…Inhibition of the MAPK pathway through PrAgL1/LF led to sustained activation of autophagy, starting at 24 hours and lasting up to 120 hours following treatment with PrAgL1/LF in the AML cell lines. Addition of CQ led to an increase in cell cytotoxicity following treatment with PrAgL1/LF, at all time points, indicating that the inhibition of the MAPK pathway in AML cells leads to the activation of autophagy, which in turn mediates cell death following treatment with PrAgL1/LF. …”
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Growth hormone treatment modulates active ghrelin levels in rats by Haddad, Haytham

“…Consequently, under such treatment, determination of active ghrelin concentration per tissue mass rather than per tissue protein is favored. …”
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Performance assessment of an integrated absorption cooling-hydrogen liquefaction system using geothermal energy by Gadalla, Mohamed

“…The results show that the mass of hydrogen gas pre-cooled by the absorption system per unit mass flow rate of geothermal water flowing through the system (n) and the amount of hydrogen liquefied per unit mass flow rate of geothermal water flowing through the system (y) increase with an increase in the geothermal source temperature. …”
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A comprehensive design and rating study of evaporative coolers and condensers. Part II. Sensitivity analysis by QURESHI, BILAL AHMED

“…For evaporative condenser design, it was seen that, for a 53% increase in the inlet relative humidity, the normalized sensitivity of the surface area increased 1.8 times in value and, for a 15 8C increase in the condenser temperature, the sensitivity increased by 3.5 times. …”
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An improved non-dimensional model of wet-cooling towers by QURESHI, BILAL AHMED

“…The first method shows a maximum decrease of 4.4 per cent in error, whereas in the second method, the maximum error was found to be 3.3 and 6.8 per cent when the inlet air was unsaturated and saturated, respectively. …”
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Water Footprint Assessment and Virtual Water Trade in the Globally Most Water-Stressed Country, Qatar by Nayla Higazy (17679453)

“…<p dir="ltr">Qatar is one of the most water stressed countries globally, despite Qatar’s aridity and its lack of freshwater resources, per capita water consumption became one of the highest in the world due to population growth, agricultural expansion, rapid urbanization and industrialization and it is expected to increase in the coming decades. …”

PSA-activated proaerolysin as a prostate specific cancer therapy by Abi-Habib, Ralph

“…Activity toward proaerolysin was decreased 10-100 fold for each of the proteases tested except PSA, which showed a 4-fold increase in activity against the modified protein. …”
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Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells by Haykal, Tony

“…Treatment with an A. cherimola seed ethanolic extract promotes a dose- and time-dependent inhibition of the proliferation of various AML cell lines, but not MSCs. …”
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Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells By Peter Nasr A thesis by Nasr, Peter

“…Treatment with an A. cherimola seed ethanolic extract promotes a dose- and time-dependent inhibition of the proliferation of various AML cell lines, but not MSCs. …”
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Malva pseudolavatera Leaf Extract Promotes ROS Induction Leading to Apoptosis in Acute Myeloid Leukemia Cells In Vitro by El Khoury, Marianne

“…Treatment of AML cell lines with M. pseudolavatera methanolic leaf extract showed a dose- and time-dependent inhibition of proliferation and a dose-dependent increase in apoptotic hallmarks such as an increase in phosphatidylserine on the outer membrane leaflet and membrane leakage in addition to DNA fragmentation. …”
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Effects of short term genotropin (rgGH) subcutaneous injection on active ghrelin concentration in rat plasma, stomach, kidney & pancreas. (c2007) by Haddad, Haytham

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Enhanced cellular uptake and photochemotherapeutic potential of a lipophilic strained Ru(II) polypyridyl complex by Mehanna, Stephanie

“…Complex 2 exhibited 35 times lower cellular concentration relative to complex 1. …”
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Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021 by Letourneau, Ian D

“…Although the global age-standardised incidence rate of appendicitis has steadily decreased between 1990 and 2021, almost half of GBD regions saw an increase of greater than 10% in their age-standardised incidence rates. …”
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The antioxidant and anticancer effects of Wild Carrot oil extract by Shebaby, Wassim Nasri

“…The effect of DCOE on the cell lines exhibited time and dose-dependent responses. …”
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The Global Economic crisis & organisation change: case studies in the UAE by Al Hashemi, Khalid

“…All of these elements should tie together in order to assure the existence of the company as a main target & then the expansion of the operation which means an increase in the profit. …”
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Organizational Change Management: A study on the need for a re-structured organization within a functional configuration by Al Marzouqi, Abdulla Ibrahim Abdulla

“…Then, critical factors that might lead to choosing one form of structure over the others will be discussed by deciding about how to tie projects to the parent organization and how to organize the project teams. …”
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Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes by Maryam Aghadi (17128819)

“…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …”

Targeting human acute myeloid leukemia cells using human recombinant arginase I (Co) - PEG5000 [HuArgl (Co) - PEG5000] - induced arginine depletion. (c2013) by Tanios, Rita Farid

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Minimization of the amplitude of the entire span of beams using mass dampers by Issa, Jimmy S.

“…Since minimizing the amplitude at one point of the beam might increase it at another point, in this work the maximum amplitude along the entire beam span is minimized. …”
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Agent Based Modeling to Optimize Supermarkets Spatial Dimensions by NASIF, MAJD

“…It is the situation where the shoppers feel that the supermarket is overloaded with people at certain times. We solved this problem by providing an optimal area range for the supermarket where we reduced the crowding levels dramatically, while avoiding unnecessary increase in space dimensions. …”
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