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201
Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model
Published 2022“…Although cardiac contractility was similar to the wild-type control, the ejection fraction was significantly increased in the mypbc3 mutants. At later stages of larval development, the mutants demonstrated an early cardiac phenotype of myocardium remodeling, concurrent cardiomyocyte hyperplasia, and increased ejection fraction as critical processes in HCM initiation to counteract the increased ventricular myocardial wall stress. …”
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202
MicroRNA-24-3p Targets Notch and Other Vascular Morphogens to Regulate Post-ischemic Microvascular Responses in Limb Muscles
Published 2020“…Exposure to hypoxia increased miR-24-3p in ECs but not in pericytes. Transfection with a miR-24-3p precursor (pre-miR-24-3p) increased miR-24-3p expression in ECs, reducing the cell survival, proliferation, and angiogenic capacity. …”
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203
Thermoelectric power of (Cu0.5Tl0.5)-1223 superconducting phase added with BaSnO3 nanoparticles
Published 2017“…In this study, we report the thermoelectric power (TEP) measurements of Cu0.5Tl0.5Ba2Ca2Cu3O10-δ added with BaSnO3 nanoparticles. BaSnO3 nanoparticles were prepared by chemical co-precipitation method, while (BaSnO3)x/(CuT1)-1223 superconducting samples with 0.00 ≤ x ≤ 1.50 wt% were prepared using the solid-state reaction method. …”
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204
Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia
Published 2019“…Curcumin induces apoptosis in B-Pre-ALL cell lines via activation of caspase-8 and truncation of BID. Curcumin treatment increased the ratio of Bax/Bcl-2 and resulted in a leaky mitochondrial membrane that led to the discharge of cytochrome c from the mitochondria to the cytoplasm, the activation of caspase 3 and the cleavage of PARP. …”
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205
Exploring Effects of Mental Stress with Data Augmentation and Classification Using fNIRS
Published 2025“…To improve our results and increase our dataset, we use data augmentation with a deep convolutional generative adversarial network (DCGAN). …”
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206
Thermal profiles of amorphous solid dispersions (ASD) in 3D printed tablets by fused deposition modelling (FDM): Production of tunable tablet doses
Published 2025“…Aptly, there was a 35% increase in solubility and a significant increase (<i>p</i> < 0.05) in dissolution rates of ibuprofen from 3D printed ASD tablets compared to printed tablets of pure ibuprofen. …”
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207
Modeling and Performance Analysis of mmWave and WiFi-Based Vehicle Communications
Published 2024“…<p dir="ltr">Vehicle -to-vehicle (V2V) communications are crucial for enhancing road network safety and efficiency. With the increasing demand for bandwidth in V2V services, exploring innovative solutions has become imperative. …”
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208
Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways
Published 2017“…Western blot analysis revealed a significant decrease in p-Erk, p-Akt, pro-caspase-3 and Bcl-2 and an increase in p53, p21, Bax and PARP proteins. …”
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209
Microstructure and Compressive Behavior of Al–Y<sub>2</sub>O<sub>3</sub> Nanocomposites Prepared by Microwave-Assisted Mechanical Alloying
Published 2019“…The effect of different levels of yttrium oxide on the microstructural and mechanical properties of the Al–Y<sub>2</sub>O<sub>3</sub> nanocomposites were investigated. The density of the Al–Y<sub>2</sub>O<sub>3</sub> nanocomposites increased with increasing Y<sub>2</sub>O<sub>3</sub> volume fraction in the aluminum matrix, while the porosity decreased. …”
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210
Differential changes in cyclic adenosine 3′-5′ monophosphate (cAMP) effectors and major Ca2+ handling proteins during diabetic cardiomyopathy
Published 2023“…Early upregulation of Epac1 transcripts was noted in diabetic hearts at Week 4, followed by increases in Epac2 mRNA, but not protein levels, at Week 12. …”
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211
Enhanced nucleate boiling heat transfer on bubble-induced assembly of 3D porous interconnected graphene oxide/silver nanowire hybrid network
Published 2022“…<p>Due to an increasing trend of size diminution, integration, and multifunctionality, the heat load on electronic devices is constantly increasing. …”
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212
Intratumoral FoxP3<sup>+</sup>Helios<sup>+</sup> Regulatory T Cells Upregulating Immunosuppressive Molecules Are Expanded in Human Colorectal Cancer
Published 2017“…Levels of CD4<sup>+</sup>FoxP3<sup>+</sup>Helios<sup>+</sup> Tregs were significantly increased in the TME. …”
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213
The effect of graphene on the activation energy of grain growth for the nanocrystalline thermoelectric n-type Bi2Te2.7Se0.3
Published 2022“…The activation energy of the pristine Bi2Te2.7Se0.3 alloy is found to be 268 kJ/mol. For the composite samples, a lower graphene weight percentage (0.05 wt.%) increased the activation energy to 270 kJ/mol. …”
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214
Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation
Published 2025“…Prist significantly increases reactive oxygen species (ROS) levels and depletes glutathione (GSH), leading to mitochondrial dysfunction and cytochrome c release. …”
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215
A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T ce...
Published 2008“…Results: WP1066 achieved an IC50 of 1.6, 2.3, and 1.5 μmol/L against melanoma cell line A375, B16, and B16EGFRvIII, respectively. …”
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216
Novel proteins implicated in lipid metabolism disorders
Published 2016“…</p><p>ANGPTL3 is a protein secreted by the liver, belonging to the angiopoietin-like family of eight proteins. …”
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217
Transport, magnetic and structural properties of(Tl0.5Pb0.5)Sr2-xCexCa2Cu3Oy compounds
Published 2000“…Resistivity, DC magnetization and X-ray diffraction measurements were performed on 6 sample with nominal composition (Tl0.5Pb 0.5)Sr2-xCexCa2Cu3 Oy, with x=0.0, 0.1, 0.2, 0.3, 0.4 and 0.5. As cerium content was increased, the transition temperature increased up to about 6 K when x=0.1. …”
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218
ZnO-Doped gC<sub>3</sub>N<sub>4</sub>Nanocapsules for Enhancing the Performance of Electroless NiP Coating─Mechanical, Corrosion Protection, and Antibacterial Properties<sub>3</sub...
Published 2023“…The highest corrosion resistance is achieved on the heat-treated NiP-C<sub>3</sub>N<sub>4</sub>/1.0 wt % ZnO coatings. Although the presence of ZnO in the C<sub>3</sub>N<sub>4</sub> nanocapsules increased its surface area and porosity, the C<sub>3</sub>N<sub>4</sub>/ZnO nanocapsules prevented localized corrosion by filling the microdefects and pores of the NiP matrix. …”
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219
Development of flexible PVDF/ BaTiO<sub>3</sub>-MoS<sub>2</sub> polymer nanocomposites for energy harvesting and gas sensing applications
Published 2024“…The electroactive, β-phase of the PVDF is shown to increase with the addition of BaTiO<sub>3</sub>–MoS<sub>2</sub> fillers as a result of the filler’s good interfacial interaction with the polymer matrix. …”
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220
Recognizing Plastic Threats in Baggage X-Rays Using Deep Networks
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