Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells By Peter Nasr A thesis by Nasr, Peter

“…Treatment with an A. cherimola seed ethanolic extract promotes a dose- and time-dependent inhibition of the proliferation of various AML cell lines, but not MSCs. Positive Annexin V staining, as well as DNA fragmentation, confirm an increase in apoptotic cell death by upregulating the expression of pro-apoptotic proteins which control both intrinsic and extrinsic pathways of apoptosis. …”
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Targeting human acute myeloid leukemia cells using human recombinant arginase I (Co) - PEG5000 [HuArgl (Co) - PEG5000] - induced arginine depletion. (c2013) by Tanios, Rita Farid

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The antioxidant and anticancer effects of Wild Carrot oil extract by Shebaby, Wassim Nasri

“…The effect of DCOE on the cell lines exhibited time and dose-dependent responses. …”
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Minimization of the amplitude of the entire span of beams using mass dampers by Issa, Jimmy S.

“…Since minimizing the amplitude at one point of the beam might increase it at another point, in this work the maximum amplitude along the entire beam span is minimized. …”
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Targeting solid tumor cells with novel photosensitive ruthenium-based metal-organic compounds. (c2016) by Farhat, Stephanie Roy

“…As for the free ligands, L-II presented major cytotoxic effect on five out of six cell lines, L-I on two cell lines, L-IV on one cell line only. …”
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Cytotoxicity of Anthrax Lethal Toxin to Human Acute Myeloid Leukemia Cells Is Nonapoptotic and Dependent on Extracellular Signal-Regulated Kinase 1/2 Activity by Abi-Habib, Ralph J.

“…We tested potency of LeTx on a panel of 11 human AML cell lines. Seven cell lines showed cytotoxic responses to LeTx. …”
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The mechanisms of resistance of anthrax lethal toxin (LeTx)-induced cytotoxicity in AML cells. (c2018) by Abou Harb, Monica

“…Our results indicate that vertical inhibition by SCH772984 rendered the resistant cell lines sensitive to the inhibition of the MAPK-pathway and showed an increased cytotoxic effect once used in combination with anthrax lethal toxin compared to the use of anthrax lethal toxin alone.…”
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Malva pseudolavatera Leaf Extract Promotes ROS Induction Leading to Apoptosis in Acute Myeloid Leukemia Cells In Vitro by El Khoury, Marianne

“…Treatment of AML cell lines with M. pseudolavatera methanolic leaf extract showed a dose- and time-dependent inhibition of proliferation and a dose-dependent increase in apoptotic hallmarks such as an increase in phosphatidylserine on the outer membrane leaflet and membrane leakage in addition to DNA fragmentation. …”
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Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes by Maryam Aghadi (17128819)

“…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …”

Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells by Bekdash, Amira

“…In this study, we target arginine auxotrophy of AML cell lines using human arginase I cobalt-PEG5000. HuArgI(Co)-PEG5000 was cytotoxic to all AML cell lines tested. …”
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Drone Based Outdoor Insulator Inspection by Waleed, Danial

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Targeting potential arginine auxotrophy in glioblastoma (GBM) cells using human recombinant arginase I (CO)-PEG 5000 [HuArgl (Co)-PEG5000]. (c2013) by Khoury, Oula

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"Development of Authentic Annual and Seasonal Lightning Thunderstorms Day Maps for Saudi Arabia" by Shwehdi, M. H.

“…Annual thunderstorms are most frequent over the southwestern parts of the country, and generally decrease towards the west and east. Due to its low latitude and less temporal change, the west coast of the Red Sea recorded the lowest Td/yr. …”
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"Thunderstorm distribution and frequency in Saudi Arabia" by Shwehdi, M. H.

“…Annual thunderstorms are most frequent over the southwestern parts of the country, and generally decrease towards the west and east. Due to its low latitude and less temporal change, the west coast of the Red Sea recorded the lowest Td/yr. …”
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Rebound effects undermine carbon footprint reduction potential of autonomous electric vehicles by Nuri C. Onat (14779093)

“…<p dir="ltr">Autonomous vehicles offer greater passenger convenience and improved fuel efficiency. …”

Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015) by Azar, Daniel Fadi

“…Furthermore, we have attempted to examine the photochemical potential of our metal-organic compound model by combining L-II and L-III in the same metal complex, thus generating four final complexes with differing net charges (from +2 to -4), and examining their activities on a panel of AML cell lines with or without exposure to blue light. Of the four final complexes Ru-II3, Ru-II2-III, Ru-II-III2 and Ru-III3, only Ru-II3 and Ru-II2-III have shown significant activity against all tested cell lines in the dark, whereas photo-activation against ML2 has shown a marked increase of potency of all four complexes, even those shown to be biologically inert in the dark, reaching IC50 values in the nM range. …”
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Comparative Effect of Sodium Butyrate and Sodium Propionate on Ovarian Cancer Migration, Invasion, and Epithelial-To-Mesenchymal Transition by Sleem, Reem

“…Methodology: The two ovarian cancer cell lines, SKOV-3 and PA-1, were treated with NaB and NaP for 24h. …”
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Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells by Al Sayyed, Fatima

“…Western blot analysis showed significant decrease in stem cell markers SOX-2 and Oct-4, and tumorigenic protein HMGA1, whereas it showed significant increase in apoptotic markers cleaved PARP and cleaved caspase-3. …”
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Characterization of the potency and mechanism of action of a novel dual-selective intermolecularly complemented version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Acute... by Farhat, Mirna

“…However, given that MMP9 was found not to be expressed in the sensitive cell lines, we were able to exclude its expression as a requirement for cytotoxicity. …”
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Kefir induces cell-cycle arrest and apoptosis in HTLV-1-negative malignant T-lymphocytes by Rizk, Sandra

“…The percent reduction in proliferation was very significant, and was dose-, and time-dependent. In both cell lines, kefir exhibited its antiproliferative effect by downregulating TGF-α and upregulating TGF-β1 mRNA expression. …”
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