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141
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142
Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways
منشور في 2015"…Flow cytometric analysis indicated that both fractions induced sub-G1 phase accumulation and increased apoptotic cell death. Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. …"
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article -
143
Enhanced cellular uptake and photochemotherapeutic potential of a lipophilic strained Ru(II) polypyridyl complex
منشور في 2019"…When compared to cisplatin, the photoproducts were more potent against all tested cell lines, implying that the complex acquired significant chemotherapeutic potential upon irradiation. …"
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article -
144
Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance
منشور في 2022"…<p>Early-stage detection of leukemia is a critical determinant for successful treatment of the disease and can increase the survival rate of leukemia patients. The factors limiting the current screening approaches to leukemia include low sensitivity and specificity, high costs, and a low participation rate. …"
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145
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
منشور في 2019"…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …"
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146
Hydrophobic Ionic Liquids for Efficient Extraction of Oil from Produced Water
منشور في 2022"…The extraction efficiency was found to increase with increasing cation alkyl chain length from C2 to C10. …"
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147
Children safety risk factors in Khorasan Razavi province
منشور في 2015"…Walking almost inevitably involves crossing a road, where the desire line of the pedestrian conflicts with the higher speed. …"
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148
Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres
منشور في 2024"…Cytotoxicity assays on human cell lines showed no toxicity towards cells at concentrations of up to 100 µg ml−1 but exhibited increased toxicity at concentrations exceeding 1000 µg ml−1. …"
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149
The challenges of driving licenses in Saudi Arabia
منشور في 2015"…The Kingdom of Saudi Arabia's booming economy has resulted in the employment of large numbers of immigrants who work as professional drivers in Saudi Arabia, who come from different cultural and social environments which contributes to an increase in the human factor as the major cause of traffic crashes. …"
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150
Decentralized PV Energy Trading: A Case Study of Residential Households in Qatar
منشور في 2024"…The results suggest that when greater PV capacity is assumed, the benefits of trading increase, and a larger proportion of household demand is met locally without the need to buy energy from the grid. …"
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151
Analysis of Partial Discharges in Oil-Impregnated Transformer Paper Insulation and PET-G Insulation
منشور في 2025"…Experiments demonstrate that a significant increase in PD activity was observed for PET-G-based cylindrical voids with heights exceeding 1 mm.…"
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152
Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans
منشور في 2024"…In addition to cell lines, we assessed the impact of BTZ in an in vivo setting using Caenorhabditis elegans (C. elegans). …"
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153
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154
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155
The distribution of toxic sources in Louisiana
منشور في 1993"…Furthermore, the greater the percentage of blacks in a community, the greater the reductions in discharges. …"
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masterThesis -
156
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157
Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Kefir's anti‑cancer potential was tested on CRC cell lines, Caco‑2 and HT‑29, through cytotoxicity, proliferation, and apoptotic assays. …"
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158
Investigating the Therapeutic Effects of Small Molecule Imipridones In Pediatric Neuroblastoma
منشور في 2020"…MYCN expression was significantly abrogated in the IMR-32 cell line with either drug treatment. The protein expression of Sox-2, Oct-4, FABP5 and HMGA1 was significantly reduced whereas cleaved PARP1 and caspase-3 and p-H2AX was increased 48 h after drug treatment in the MYCN-amplified IMR-32 cell line. …"
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masterThesis -
159
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160
Road safety and traffic medicine in Iran: Achievements and challenges
منشور في 2015"…The reduction in number of deaths happened despite a four-fold increase in number of motor vehicles. Some of the interventions that might be contributing to this achievement include the following: a) the new traffic law passed in 2010 that replaced the previous one dating back to 1968. …"