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141
Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
منشور في 2023"…</p><h3>Conclusion</h3><p dir="ltr">To our knowledge this is the first report of the stable non-lethal increase of SLFN11 expression in a cancer cell line. …"
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142
Dual Targeting of Matrix Metalloproteases and the MAPK Pathway in Acute Myeloid Leukemia Cells Using an MMP-activated anthrax lethal toxin (PrAgL1/LF)
منشور في 2020"…Our results demonstrate that vertical inhibition does offer increased potency in comparison to single targeting of the MAPK pathway when working with sensitive cell lines that are dependent on the cascade. …"
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masterThesis -
143
Is board compensation excessive?
منشور في 2017"…For companies that overpay, the average excess compensation is greater than $60,000 per director, while directors that are underpaid receive about $33,000 less than predicted. …"
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article -
144
Malva pseudolavatera Leaf Extract Promotes ROS Induction Leading to Apoptosis in Acute Myeloid Leukemia Cells in Vitro
منشور في 2020"…Treatment of AML cell lines with M. pseudolavatera methanolic leaf extract showed a dose- and time-dependent inhibition of proliferation and a dose-dependent increase in apoptotic hallmarks such as an increase in phosphatidylserine on the outer membrane leaflet and membrane leakage in addition to DNA fragmentation. …"
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masterThesis -
145
Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells
منشور في 2019"…Treatment with an A. cherimola seed ethanolic extract promotes a dose- and time-dependent inhibition of the proliferation of various AML cell lines, but not MSCs. Positive Annexin V staining, as well as DNA fragmentation, confirm an increase in apoptotic cell death by upregulating the expression of pro-apoptotic proteins which control both intrinsic and extrinsic pathways of apoptosis. …"
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article -
146
Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells By Peter Nasr A thesis
منشور في 2020"…Treatment with an A. cherimola seed ethanolic extract promotes a dose- and time-dependent inhibition of the proliferation of various AML cell lines, but not MSCs. Positive Annexin V staining, as well as DNA fragmentation, confirm an increase in apoptotic cell death by upregulating the expression of pro-apoptotic proteins which control both intrinsic and extrinsic pathways of apoptosis. …"
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masterThesis -
147
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148
The antioxidant and anticancer effects of Wild Carrot oil extract
منشور في 2012"…The effect of DCOE on the cell lines exhibited time and dose-dependent responses. …"
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article -
149
Minimization of the amplitude of the entire span of beams using mass dampers
منشور في 2017"…Since minimizing the amplitude at one point of the beam might increase it at another point, in this work the maximum amplitude along the entire beam span is minimized. …"
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conferenceObject -
150
Targeting solid tumor cells with novel photosensitive ruthenium-based metal-organic compounds. (c2016)
منشور في 2016"…As for the free ligands, L-II presented major cytotoxic effect on five out of six cell lines, L-I on two cell lines, L-IV on one cell line only. …"
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masterThesis -
151
Cytotoxicity of Anthrax Lethal Toxin to Human Acute Myeloid Leukemia Cells Is Nonapoptotic and Dependent on Extracellular Signal-Regulated Kinase 1/2 Activity
منشور في 2013"…We tested potency of LeTx on a panel of 11 human AML cell lines. Seven cell lines showed cytotoxic responses to LeTx. …"
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article -
152
The mechanisms of resistance of anthrax lethal toxin (LeTx)-induced cytotoxicity in AML cells. (c2018)
منشور في 2018"…Our results indicate that vertical inhibition by SCH772984 rendered the resistant cell lines sensitive to the inhibition of the MAPK-pathway and showed an increased cytotoxic effect once used in combination with anthrax lethal toxin compared to the use of anthrax lethal toxin alone.…"
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masterThesis -
153
Malva pseudolavatera Leaf Extract Promotes ROS Induction Leading to Apoptosis in Acute Myeloid Leukemia Cells In Vitro
منشور في 2020"…Treatment of AML cell lines with M. pseudolavatera methanolic leaf extract showed a dose- and time-dependent inhibition of proliferation and a dose-dependent increase in apoptotic hallmarks such as an increase in phosphatidylserine on the outer membrane leaflet and membrane leakage in addition to DNA fragmentation. …"
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article -
154
Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes
منشور في 2022"…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …"
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155
Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells
منشور في 2013"…In this study, we target arginine auxotrophy of AML cell lines using human arginase I cobalt-PEG5000. HuArgI(Co)-PEG5000 was cytotoxic to all AML cell lines tested. …"
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article -
156
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157
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158
"Development of Authentic Annual and Seasonal Lightning Thunderstorms Day Maps for Saudi Arabia"
منشور في 2006"…Annual thunderstorms are most frequent over the southwestern parts of the country, and generally decrease towards the west and east. Due to its low latitude and less temporal change, the west coast of the Red Sea recorded the lowest Td/yr. …"
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article -
159
"Thunderstorm distribution and frequency in Saudi Arabia"
منشور في 2005"…Annual thunderstorms are most frequent over the southwestern parts of the country, and generally decrease towards the west and east. Due to its low latitude and less temporal change, the west coast of the Red Sea recorded the lowest Td/yr. …"
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article -
160
Rebound effects undermine carbon footprint reduction potential of autonomous electric vehicles
منشور في 2023"…<p dir="ltr">Autonomous vehicles offer greater passenger convenience and improved fuel efficiency. …"