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Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases
منشور في 2010"…For example, a few years ago an extrahepatic metastasis effectively eliminated surgical resection, but a combination of chemotherapeutic options and surgical techniques has expanded the indications for resection and increased the population of patients who may benefit.1,2 Neoadjuvant chemotherapy has increased the resectability rate by 11% to 37%.1 Unfortunately, greater than 80% of patients undergoing hepatic resection will have recurrences, mostly within the first 2 years.2 Nonetheless, the only hope for cure is resection, and prior surgical dogma based on the number of lesions, size of the tumor-free resection margin, and presence of resectable extrahepatic disease must be questioned.3- 5 The current standard approach to surgical planning is contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI) for specific tumor characteristics or contraindications to CT.6 Several series showed that focal extrahepatic disease, an isolated pulmonary lesion, can be safely resected, with 5-year survival rates of 29% to 58%.7,8 In 1 series,7 17 of 30 patients required 3 or more resections. …"
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62
The chemical analysis of Lebanese olive oil and the influence of oil enriched diet on Plasma Lipid profile in rats. (c2002)
منشور في 2002"…In the second half of this century, emphasis on diet related diseases increased as the major cause of mortality shifted from infections to chronic diseases. …"
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masterThesis -
63
A genome-wide transcriptomic analysis of embryos fathered by obese males in a murine model of diet-induced obesity
منشور في 2022"…To this end, we investigated whether paternal obesity is associated with gene expression changes in eight-cell stage embryos fathered by males on a high-fat diet. We used single embryo RNA-seq to compare the gene expression profile of embryos generated by males on a high fat (HFD) versus control (CD) diet. …"
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64
A marking technique for intraoperative localization of small liver metastases before systemic chemotherapy
منشور في 2009"…Preoperative chemotherapy is increasingly used prior to resection of colorectal liver metastases (CLM). …"
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65
Repeat hepatectomy for recurrent colorectal liver metastases is associated with a high survival rate
منشور في 2011"…Background: The outcome after a repeat hepatectomy for recurrent colorectal liver metastases (CLM) is not well defined. The present study examined the morbidity, mortality and long-term survivals after a repeat hepatectomy for recurrent CLM. …"
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66
Body surface area and body weight predict total liver volume in Western adults
منشور في 2002"…Computed tomography (CT) is used increasingly to measure liver volume in patients undergoing evaluation for transplantation or resection. …"
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67
Artificial Intelligence for Detecting and Quantifying Fatty Liver in Ultrasound Images: A Systematic Review
منشور في 2022"…Conclusion: AI-supported systems show potential performance increases in detecting and quantifying steatosis, NASH, and liver fibrosis in NAFLD patients. …"
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68
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Novel paclitaxel formulations solubilized by parenteral nutrition nanoemulsions for application against glioma cell lines
منشور في 2016"…The zeta potential of linoleic had a greater negative value than that of Intralipid.Loading efficiencies for paclitaxel were 70.4–80.2% and 44.2–57.4% for Clinoleic and Intralipid formulations, respectively. …"
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70
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71
Metformin Induces Different Responses in Clear Cell Renal Cell Carcinoma Caki Cell Lines
منشور في 2019"…Our findings demonstrate a differential response between the two ccRCC cell lines studied, with Caki-2 cells being more sensitive to metformin compared to Caki-1 cells, which could be linked to the differential expression of HIF-1 despite both cell lines carrying a wild-type VHL. …"
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72
Impaired Liver Size and Compromised Neurobehavioral Activity are Elicited by Chitosan Nanoparticles in the Zebrafish Embryo Model
منشور في 2019"…Although no single sign of cardiotoxicity was observed upon exposure to 200 mg/L of ChNPs, as judged by heartbeat rate, the corrected QT interval (QTc, which measures the time between the start of the Q wave and the end of the T wave in the heart's electrical cycle), maximum cardiac arrest, and ejection fraction assays, the same dosage elicited the impairment of both liver size (decreased liver size, but without steatosis and lipid yolk retention) and neurobehavioral activity (increased movement under different light conditions). …"
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73
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74
Methylation at global LINE-1 repeats in human blood are affected by gender but not by age or natural hormone cycles
منشور في 2011"…However, the previously reported increase of LINE-1 methylation in males was reconfirmed. …"
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75
Assessment of tropospheric NO<sub>2</sub> concentrations over greater Doha using Sentinel-5 TROPOspheric monitoring instrument (TROPOMI) satellite data: Temporal analysis, 2018–202...
منشور في 2024"…<p dir="ltr">This study presents a temporal evaluation of the tropospheric NO<sub>2</sub> column densities over Greater Doha using TROPOMI satellite data from May 2018 to December 2023, and an assessment of the impact of the preparations and hosting of the FIFA Football World Cup Qatar 2022, on NO<sub>2</sub> levels before, during and after the tournament over Greater Doha. …"
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76
Perinatal exposure to PFOS and sustained high-fat diet promote neurodevelopmental disorders via genomic reprogramming of pathways associated with neuromotor development
منشور في 2024"…It’s also known that obesity and consumption of a high fat diet have negative effects on the brain, impairs cognition and increases the risk for the development of dementia. …"
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77
Effects of lipid administration on liver apoptotic signals in a mouse model of total parenteral nutrition (TPN)
منشور في 2004"…Interestingly, we have recently observed an increase in hepatocyte apoptosis with administration of TPN. …"
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78
Combinatory effect of diet and exercise on brain derived neurotrophic factor expression, cognitive function and behavioral phenotypes of psychiatric disorders. (c2017)
منشور في 2017"…We have found that combining a high protein diet with exercise has an additive effect on the induction of brain Bdnf expression. …"
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masterThesis -
79
Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…Methods and results Using the WST assay, the pentane fraction (F1) and 1:1 pentane:diethyl ether fraction (F2) were shown to possess the highest cytotoxicity against both cell lines. Flow cytometric analysis revealed that both fractions induced the accumulation of cells in the sub-G1 phase, increase in apoptotic cell death and chromatin condensation. …"
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