Single-Cell Transcriptome Analysis Revealed Heterogeneity and Identified Novel Therapeutic Targets for Breast Cancer Subtypes by Radhakrishnan Vishnubalaji (3563306)

“…Given the aggressive nature and lack of targeted therapies for TNBC, elevated expression of ENO1, FDPS, CCT6A, TUBB2A, and PGK1 predicted worse relapse-free survival (RFS) in basal BC (n = 442), while elevated expression of ENO1, FDPS, CCT6A, and PGK1 was observed in the most aggressive BLIS TNBC subtype. …”

A multi-targeted approach to identify potential flavonoids against three targets in the SARS-CoV-2 life cycle by Sanjay Kumar (8853)

“…These observations were complimented by the 100 ns molecular dynamics simulation and binding free energy analysis, which showed a considerable stability of docked bioflavonoids in the active site of SARS-CoV-2 target proteins. …”

Deep learning-based cross-device standardization of surface-enhanced Raman spectroscopy for enhanced bacterial recognition by Sakib Mahmud (22652357)

“…<p dir="ltr">Surface-enhanced Raman spectroscopy (SERS) is a powerful, label-free technique for pathogen detection; however, its broader adoption in clinical diagnostics is hindered by inconsistent spectral quality across portable and laboratory-grade instruments, limited cross-device reproducibility, and the poor generalizability of existing machine learning approaches. …”

Attitudes, motivators, and barriers toward influenza vaccination for children: a study from a conflict-ridden country by Wesam S. Ahmed (10170053)

“…<h3>Background</h3><p dir="ltr">Despite the increased recommendations for influenza vaccination, particularly among high-risk groups such as young children, Yemen lacks an influenza vaccination program, and the influenza vaccine is not included in the national immunization regime. …”

The role of IT governance in enhancing the competitiveness of for-profit private schools' business by Jasim, Alaa H

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Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis by Meritxell Espino‐Guarch (22565774)

“…Further, chronic Gln accumulation and decreased proteolysis were found to induce the early onset of an age‐related muscle phenotype.…”

Urban Geometry: The Effect of Height Diversity and Buildings Configuration on Thermal Performance and Cooling Load at Urban Scale. A Case Study in Dubai / UAE by SHAREEF, SUNDUS LUAY

“…The variation along the short direction of the urban block has a greater positive effect and the saving in cooling energy consumption reaches 4.6 %. …”
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Experimental and modeling analysis of p-type Bi₀.₄Sb₁.₆Te₃ and graphene nanocomposites by Aicha S. Lemine (17148352)

“…The synthesized pristine Bi_0.4Sb_1.6Te₃ and 0.05wt% GNS/Bi_0.4Sb_1.6Te₃ nanocomposites at different addition times of GNS have exhibited a single-phase and artifact-free bulk nanocrystalline Bi_0.4Sb_1.6Te₃ with nanocrystals size of 17 nm. …”

Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications by Jingxuan Shan (4711089)

“…High expression of <i>CCL5</i> in breast tumors was significantly associated with an increased OVS in all BC patients, but particularly in TNBC/Basal-like patients. …”

Novel proteins implicated in lipid metabolism disorders by Nature Research (16552612)

“…</p><p>ANGPTL4 is a protein that is activated during fasting, decreasing the release of free fatty acids from circulating triglyceride-rich lipoproteins. …”

Phase state of secondary organic aerosol in chamber photo-oxidation of mixed precursors by Yu Wang (12152)

“…Although less important than RH and MR_org/inorg, the SOA composition plays a second-order role, with differences in the liquid-to-nonliquid transition at moderate MR_org/inorg of ∼ 1 observed between biogenic-only (anthropogenic-free) and anthropogenic-containing VOC systems. Considering the combining role of the RH and chemical composition in aerosol phase state, the BF decreased monotonically with increasing hygroscopic growth factor (GF), and the BF was ∼ 0 when GF was larger than 1.15. …”

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants by Bin, Zhou

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Can Ease of Doing Business Shorten the Distance and Attract Foreign Direct Investment by AL KHOORI, YOUSUF

“…Abstract Due to the accelerating pace of globalization, Multinational Enterprises (MNEs) have increasingly employed foreign direct investment (FDI) to enter foreign markets. …”
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Design, Evaluation and Techno-Economic Analysis of a Hybrid Solar-Wind Power Generation System in UAE by Kulkarni, Chaitanya Bipin

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Liver resection for liver metastases from nondigestive endocrine cancer by Andreou, Andreas

“…After median follow-up of 20 months (range, 1–144), the 5-year overall and recurrence-free survival rates were 58% and 37%, respectively. …”
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Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 by Olfa Khalifa (10914452)

“…Then starved the cells for 6h in DMEM containing 1% fatty-acid-free bovine serum albumin. Following the starvation, a 16h incubation in DMEM containing increasing concentrations of OA (0–500 µM) at 37 °C was performed, and steatosis was quantified by triglycerides quantification, Bodipy staining, and quantification of the expression of perilipin genes family. …”

Global, regional, and national stillbirths at 20 weeks' gestation or longer in 204 countries and territories, 1990–2021: findings from the Global Burden of Disease Study 2021 by Comfort, Haley

“…Findings: In 2021, the global stillbirth rate was 23·0 (95% uncertainty interval [UI] 19·7–27·2) per 1000 births (stillbirths plus livebirths) at 20 weeks' gestation or longer, compared to 16·1 (13·9–19·0) per 1000 births at 28 weeks' gestation or longer. …”
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Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021 by Austin, Carter

“…In 2021, sub-Saharan Africa had the highest PUV of 999·9 (857·4–1154·2) per 100 000 population, but this was a 64·5% (58·8–69·4) reduction in PUV from 2003 to 2021. …”
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Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for th... by Jaimie D Steinmetz (18015919)

“…</p><p><br></p><h3>Findings</h3><p dir="ltr">Global crude prevalence of avoidable vision impairment and blindness in adults aged 50 years and older did not change between 2010 and 2019 (percentage change −0·2% [95% UI −1·5 to 1·0]; 2019 prevalence 9·58 cases per 1000 people [95% IU 8·51 to 10·8], 2010 prevalence 96·0 cases per 1000 people [86·0 to 107·0]). …”

Physical and chemical properties of black carbon and organic matter from different combustion and photochemical sources using aerodynamic aerosol classification by Dawei Hu (2186113)

“…The dynamic shape factor (χ) of BC particles and material density (ρ_m) of organic aerosols was investigated by coupling a charging-free Aerodynamic Aerosol Classifier (AAC) with a Centrifugal Particle Mass Analyzer (CPMA) and a Scanning Mobility Particle Sizer (SMPS). …”