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441
Landscape of childhood epilepsies – A multi-ethnic population-based study
منشور في 2022"…At the last follow up, only 36% of patients were seizure-free and 12% (170/1422) had a history of status epilepticus. …"
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442
Comparative life cycle assessment of sustainable energy carriers including production, storage, overseas transport and utilization
منشور في 2021"…<p dir="ltr">Countries are under increasing pressure to reduce greenhouse gas emissions as an act upon the Paris Agreement. …"
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443
Global, regional, and national burden of household air pollution, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
منشور في 2025"…The rate of global, HAP-attributable DALYs in 2021 was 1500·3 (95% UI 1028·4–2195·6) age-standardised DALYs per 100 000 population, a decline of 63·8% since 1990, when HAP-attributable DALYs comprised 4147·7 (3101·4–5104·6) age-standardised DALYs per 100 000 population. …"
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444
The Effect of High Dose Isoflavone Supplementation on Serum Reverse T3 in Euthyroid Men With Type 2 Diabetes and Post-menopausal Women
منشور في 2018"…Thyroid stimulating hormone (TSH) serum concentrations increased while free thyroxine (fT<sub>4</sub>) concentrations decreased with 3 months of SPI compared to SP supplementation for both men and women. rT<sub>3</sub> correlated with TSH in both studies (<i>p</i> = 0.03) but not with either fT<sub>3</sub> or fT<sub>4</sub>. fT<sub>3</sub> levels did not differ between the SPI and SP preparations.…"
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445
Caloric restriction reduces trabecular bone loss during aging and improves bone marrow adipocyte endocrine function in male mice
منشور في 2024"…<h3>Introduction</h3><p dir="ltr">Caloric restriction (CR) is a nutritional intervention that increases life expectancy while lowering the risk for cardio-metabolic disease. …"
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446
Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analy...
منشور في 2024"…The most pronounced decline was in children younger than 5 years, with a 79·2% (72·4–84·6) decrease in diarrhoeal deaths. Global YLLs also decreased substantially, from 186 million (147–221) in 1990 to 51·4 million (39·9–65·9) in 2021. …"
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447
Rapid mercury removal using living indigenous microalgal communities for water treatment applications
منشور في 2025"…Comprehensive isotherm analysis revealed the Dubinin-Radushkevich model provided the best fit (R<sup>2</sup> = 0.998), indicating physical adsorption as the predominant mechanism, as the calculated mean free energy (E = 5.00 kJ/mol) falls within the 1–8 kJ/mol range characteristic of physical adsorption. …"
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448
Single-Cell Transcriptome Analysis Revealed Heterogeneity and Identified Novel Therapeutic Targets for Breast Cancer Subtypes
منشور في 2023"…Given the aggressive nature and lack of targeted therapies for TNBC, elevated expression of ENO1, FDPS, CCT6A, TUBB2A, and PGK1 predicted worse relapse-free survival (RFS) in basal BC (n = 442), while elevated expression of ENO1, FDPS, CCT6A, and PGK1 was observed in the most aggressive BLIS TNBC subtype. …"
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449
A multi-targeted approach to identify potential flavonoids against three targets in the SARS-CoV-2 life cycle
منشور في 2022"…These observations were complimented by the 100 ns molecular dynamics simulation and binding free energy analysis, which showed a considerable stability of docked bioflavonoids in the active site of SARS-CoV-2 target proteins. …"
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450
Deep learning-based cross-device standardization of surface-enhanced Raman spectroscopy for enhanced bacterial recognition
منشور في 2026"…<p dir="ltr">Surface-enhanced Raman spectroscopy (SERS) is a powerful, label-free technique for pathogen detection; however, its broader adoption in clinical diagnostics is hindered by inconsistent spectral quality across portable and laboratory-grade instruments, limited cross-device reproducibility, and the poor generalizability of existing machine learning approaches. …"
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451
Attitudes, motivators, and barriers toward influenza vaccination for children: a study from a conflict-ridden country
منشور في 2024"…<h3>Background</h3><p dir="ltr">Despite the increased recommendations for influenza vaccination, particularly among high-risk groups such as young children, Yemen lacks an influenza vaccination program, and the influenza vaccine is not included in the national immunization regime. …"
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452
Branched-chain amino acids mediate resilience to chronic social defeat stress by activating BDNF/TRKB signaling
منشور في 2019"…We also tested the effect of voluntary exercise and high protein diets on susceptibility to stress. Mice exposed to chronic stress displayed increased susceptibility and social avoidance. …"
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453
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454
Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis
منشور في 2025"…Further, chronic Gln accumulation and decreased proteolysis were found to induce the early onset of an age‐related muscle phenotype.…"
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455
Urban Geometry: The Effect of Height Diversity and Buildings Configuration on Thermal Performance and Cooling Load at Urban Scale. A Case Study in Dubai / UAE
منشور في 2018"…The variation along the short direction of the urban block has a greater positive effect and the saving in cooling energy consumption reaches 4.6 %. …"
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456
Experimental and modeling analysis of p-type Bi<sub>0</sub>.<sub>4</sub>Sb<sub>1</sub>.<sub>6</sub>Te<sub>3</sub> and graphene nanocomposites
منشور في 2022"…The synthesized pristine Bi<sub>0.4</sub>Sb<sub>1.6</sub>Te<sub>3</sub> and 0.05wt% GNS/Bi<sub>0.4</sub>Sb<sub>1.6</sub>Te<sub>3</sub> nanocomposites at different addition times of GNS have exhibited a single-phase and artifact-free bulk nanocrystalline Bi<sub>0.4</sub>Sb<sub>1.6</sub>Te<sub>3</sub> with nanocrystals size of 17 nm. …"
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457
Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications
منشور في 2019"…High expression of <i>CCL5</i> in breast tumors was significantly associated with an increased OVS in all BC patients, but particularly in TNBC/Basal-like patients. …"
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458
Novel proteins implicated in lipid metabolism disorders
منشور في 2016"…</p><p>ANGPTL4 is a protein that is activated during fasting, decreasing the release of free fatty acids from circulating triglyceride-rich lipoproteins. …"
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459
Phase state of secondary organic aerosol in chamber photo-oxidation of mixed precursors
منشور في 2021"…Although less important than RH and MR<sub>org/inorg</sub>, the SOA composition plays a second-order role, with differences in the liquid-to-nonliquid transition at moderate MR<sub>org/inorg</sub> of ∼ 1 observed between biogenic-only (anthropogenic-free) and anthropogenic-containing VOC systems. Considering the combining role of the RH and chemical composition in aerosol phase state, the BF decreased monotonically with increasing hygroscopic growth factor (GF), and the BF was ∼ 0 when GF was larger than 1.15. …"
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460