Precision meets repurposing: Innovative approaches in human papillomavirus and Epstein-Barr virus-driven cancer therapy حسب Queenie Fernandes (14557388)

"…HPV and EBV are known to be increasingly involved in the pathogenesis of various classes of cancers like cervical, head and neck, colorectal, breast, oral and anogenitial. …"

A novel inhibitor of STAT3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells حسب Abou-Ghazal, Mohamed K.

"…Long-term survival (>78 days) was observed in 80% of mice with established intracerebral syngeneic melanoma treated with 40 mg/kg of WP1066 in contrast to control mice who survived for a median of 15 days. Although WP1066 did not induce immunological memory or enhance humoral responses to EGFRvIII, this compound reduced the production of immunosuppressive cytokines and chemokines (TGF-β, RANTES, MCP-1, VEGF), markedly inhibited natural and inducible Treg proliferation, and significantly increased cytotoxic immune responses of T cells. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T ce... حسب Abou-Ghazal, Mohamed

"…Long-term survival (>78 days) was observed in 80% of mice with established intracerebral syngeneic melanoma treated with 40 mg/kg of WP1066 in contrast to control mice who survived for a median of 15 days. Although WP1066 did not induce immunologic memory or enhance humoral responses to EGFRvIII, this compound reduced the production of immunosuppressive cytokines and chemokines (transforming growth factor-β, RANTES, MCP-1, vascular endothelial growth factor), markedly inhibited natural and inducible Treg proliferation, and significantly increased cytotoxic immune responses of T cells. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Incidence of Sedation-Related Complications With Propofol Use During Advanced Endoscopic Procedures حسب Azar, Riad

"…We performed a regression analysis to compare characteristics of patients requiring AMs (AM+) with those who did not (AM−). Results A total of 799 patients were enrolled over 7 months. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Initial risk assessment for pulmonary hypertension in patients with COPD حسب Yammine, Joe

"…Background Pulmonary hypertension (PH) is a comorbidity associated with increased mortality in chronic obstructive pulmonary disease (COPD) patients. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Patterns of Rectal Temperature and Shipping Fever Incidence in Horses Transported Over Long-Distances حسب Yousuke Maeda (18174976)

"…Clinical signs of shipping fever was observed in 25 of the 53 horses (47.2%), of which 10 horses (18.9%) exhibited fever at the end of transportation and 15 horses (28.3%) did not. This showed that horses that develop shipping fever do not necessarily present with fever at the end of transportation. …"

Non-medical cancer support for Qatari women حسب Nature Research (16552612)

"…<p>Patients' perceptions of the importance of psychosocial support is becoming increasingly important for improving the quality of patient-centred care, but information about the attitudes of female cancer patients in Arab and Muslim populations is scarce. …"

The Prevalence and Genetic Spectrum of Familial Hypercholesterolemia in Qatar Based on Whole Genome Sequencing of 14,000 Subjects حسب Ilhame Diboun (3522413)

"…<p dir="ltr">Familial hypercholesterolemia (FH) is an inherited disease characterized by reduced efficiency of low-density lipoprotein-cholesterol (LDL-C) removal from the blood and, consequently, an increased risk of life-threatening early cardiovascular complications. …"

Tranexamic Acid for Traumatic Injury in the Emergency Setting: A Systematic Review and Bias-Adjusted Meta-Analysis of Randomized Controlled Trials حسب Pieter Francsois, Fouche

"…No compelling evidence of increased vascular occlusive events emerged (OR 0.96, 95% CI 0.73 to 1.27). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Enhancing eggplant (Solanum melongena L.) yield and water use efficiency through optimized irrigation and nitrogen practices in open field conditions حسب Adewale Suraj, Bello

"…While average fruit weight did not differ significantly across nitrogen levels, the highest fruit yield was recorded under F1 and F2 treatments. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Development and Validation of the Motivation for Tutoring Questionnaire in Problem-Based Learning Programs حسب Salah Eldin, Kassab

"…In addition, tutoring efficacy scores significantly increased by years of tutoring experience and predicted 38% of the variance in self-rated tutoring skills scores. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Unpacking the asymmetric impact of exchange rate volatility on trade flows: A study of selected developed and developing Asian economies حسب Umar Nawaz Kayani (17131781)

"…The non-linear models yielded more significant findings, while the linear models did not indicate any significant effects of exchange rate volatility on trade flows. …"

Applying the ecosystem services - EBM framework to sustainably manage Qatar's coral reefs and seagrass beds حسب Lucia M., Fanning

"…Given the current natural and anthropogenic threats facing Qatar's marine environment and the consequential expected decline in ecosystem services, this paper examines the potential application of the Ecosystem Services-EBM framework developed by Granek et al. (2010) to sustainably manage Qatar's coral reef and seagrass bed ecosystems. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Heuristics. (c2006) حسب Kallab, Chadi

احصل على النص الكامل
احصل على النص الكامل

Diagnostic, Prognostic, and Mechanistic Biomarkers of Diabetes Mellitus-Associated Cognitive Decline حسب Hanan Ehtewish (17149825)

"…Aging, poor glycemic control, hypoglycemia and hyperglycemic episodes, depression, and vascular complications are associated with increased risk of dementia. Conclusive research studies that have attempted to find specific biomarkers are limited. …"

Exploring environmental, social, and governance and bank performance in the Gulf Cooperation Council region حسب Jaywant Michael (17541642)

"…<p dir="ltr">Corporate strategies today are shaped by the increased importance given by companies, investors, and regulators to environmental, social, and governance (ESG) activities. …"

Antimicrobial resistant strains of Salmonella typhi: The role of illicit antibiotics sales, misuse, and self-medication practices in Pakistan حسب Omer A. Shaikh (16855107)

"…The MDR strain links to the H58 haplotype, and its XDR variant exhibits fluoroquinolone resistance due to an IncY plasmid. The increasing prevalence of these resistant strains is concerning, given the global antimicrobial resistance (AMR) issue. …"

Development of a multi-zone adiabatic reactor optimization framework for oxidative coupling of methane حسب Murtaza Ali Khan (22804274)

"…Additionally, little attention has been given to distributing O₂ along the reactor or using interstage cooling to smooth temperature variations inside the OCM reactor and improve performance. …"

Bootstrap-based Aggregations and their Stability in Feature Selection حسب Salman, Reem Elfatih

احصل على النص الكامل

Parallel Algorithms for Distinguishing Nondeterministic Finite State Machines حسب Ali, Mustafa

احصل على النص الكامل