-
581
Inositol 1,4,5-Trisphosphate Receptors in Hypertension
منشور في 2018"…This involves a phenotypic switch of VSMCs as well as an alteration of cytoplasmic Ca<sup>2+</sup> signaling machinery, a phenomena tightly related to the aging process. Several lines of evidence implicate changes in expression/function levels of IP<sub>3</sub>R isoforms in the development of hypertension, VSMC phenotypic switch, and vascular aging. …"
-
582
Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway
منشور في 2021"…SNG treatment increased Bax/Bcl-2 ratio, which contributed to a leaky mitochondrial membrane leading to cytochrome c release accompanied by caspase activation. …"
-
583
A possible culprit for refractory angina
منشور في 2015"…</p><p>This may implicate lipoprotein(a) as having a causal role in refractory angina, but the findings still need to be confirmed by testing a control group of patients who have coronary heart disease but not refractory angina.</p><p>An increased lipoprotein(a) level is known to be highly heritable, and is believed to promote hardening of the arteries by trapping cholesterol in the inner linings of blood vessels, promoting clot formation, recruiting inflammatory cells, or binding pro-inflammatory phospholipids.…"
-
584
The SREBP-dependent regulation of cyclin D1 coordinates cell proliferation and lipid synthesis
منشور في 2022"…Consequently, inactivation of SREBP1 in human liver and breast cancer cell lines reduces the expression of cyclin D1 and attenuates Rb phosphorylation. …"
-
585
Optimizing microgrid efficiency: Coordinating commercial and residential demand patterns with shared battery energy storage
منشور في 2024"…Moreover, considering DTR for transmission lines, instead of fixed thermal rating, improves the PAR and DPS up to 28.52 % and 41.06 % respectively. …"
-
586
Enhanced generation of beta cell precursors and functional insulin-secreting cells from human pluripotent stem cells
منشور في 2023"…The 3D-beta cells secreted C-peptide in response to increased glucose concentrations as well as membrane depolarization indicating they possess functionality and secretory insulin granules. …"
-
587
Augmented Reality in Medical Practice: From Spine Surgery to Remote Assistance
منشور في 2021"…The accessibility of this information often relies on the physical presence of technical and medical specialists in the OR, which is increasingly difficult due to the number of limitations imposed by the COVID emergency to avoid overcrowded environments or external personnel. …"
-
588
ACTB Loss-of-Function Mutations Result in a Pleiotropic Developmental Disorder
منشور في 2017"…<i>ACTB</i> mRNA expression levels in lymphoblastic lines and fibroblasts derived from affected individuals were decreased in comparison to those in control cells. …"
-
589
PDX1<sup>−</sup>/NKX6.1<sup>+</sup> progenitors derived from human pluripotent stem cells as a novel source of insulin‐secreting cells
منشور في 2020"…Also, the 3D-beta cells secreted C-peptide in response to increased glucose concentrations indicating their functionality.…"
-
590
-
591
The Impact of Total Quality Management for achieving Sustainable Project Management
منشور في 2021"…Implication: The leaders and management in the public sector should give importance to the operational focus, customer focus and workforce focus in drafting project management strategies and practices. …"
احصل على النص الكامل
-
592
Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
منشور في 2024"…Furthermore, induced pluripotent stem cell (iPSC) lines lacking RFX6 were generated using CRISPR/Cas9. …"
-
593
What’s So Great About Home?
منشور في 2008"…And I prefer not to label myself because I feel when writing about women that I am writing by extension to all human beings.”5 Notwithstanding the above, I propose in this essay to give La maison sans racines and Hikāyat Zahra the general description of a literature of displacement. …"
احصل على النص الكامل
احصل على النص الكامل
article