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281
Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway
Published 2023“…Our study investigated NSP‐B's antitumor effects on MM cell lines (U266 and RPMI8226) and the involved molecular mechanisms. …”
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282
Evaluation of Estrone Liposomes using Microfluidics for Breast Cancer Therapy
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doctoralThesis -
283
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284
CEO gender and managerial entrenchment
Published 2020“…We find that the presence of female CEO decreases the turnover-performance sensitivity, increases the E-index, and inflates CEO compensation. …”
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285
The Effect of Auditor Characteristics on the Quality of Segment Disclosures of Diversified Firms
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doctoralThesis -
286
Frugal innovation as a source of sustainable entrepreneurship to tackle social and environmental challenges
Published 2023“…<p>Sustainable entrepreneurs have increasingly faced challenges in achieving triple-bottom-line objectives. …”
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287
Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation
Published 2025“…In this study, we demonstrate that Prist effectively inhibits the proliferation of T-ALL cell lines (Jurkat and Molt 4) by inducing G0/G1 cell cycle arrest and triggering intrinsic and extrinsic caspase-dependent apoptosis. …”
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288
Macular ultrastructural features in amblyopia using high-definition optical coherence tomography
Published 2013“…Enhanced high-definition single line macular scans of amblyopic eyes were obtained using SD-OCT and compared with fellow eyes. …”
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289
Tumor protease-activated fusion toxins
Published 2003“…In this study, we demonstrate that DTU2GMCSF is highly potent against AML cell lines in vitro and is not toxic to normal cells both in vitro and in vivo. …”
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masterThesis -
290
Protein arginine methyltransferase 5 (PRMT5) activates WNT/β‐catenin signalling in breast cancer cells via epigenetic silencing of DKK1 and DKK3
Published 2023“…In this study, we show that PRMT5 is overexpressed in breast cancer cell lines, and that it promotes WNT/β-CATENIN proliferative signalling through epigenetic silencing of pathway antagonists, <i>DKK1</i> and <i>DKK3</i>, leading to enhanced expression of <i>c-MYC</i>, <i>CYCLIN D1</i> and <i>SURVIVIN</i>. …”
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291
Inositol 1,4,5-Trisphosphate Receptors in Hypertension
Published 2018“…This involves a phenotypic switch of VSMCs as well as an alteration of cytoplasmic Ca<sup>2+</sup> signaling machinery, a phenomena tightly related to the aging process. Several lines of evidence implicate changes in expression/function levels of IP<sub>3</sub>R isoforms in the development of hypertension, VSMC phenotypic switch, and vascular aging. …”
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292
Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway
Published 2021“…SNG suppressed cell growth and induced apoptosis via downregulation of the constitutively active JAK/STAT pathway in all the NSCLC cell lines. siRNA silencing of STAT3 in NSCLC cells further confirmed the involvement of the JAK/STAT signaling cascade. …”
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293
Co‐operative learning for Children with an Autistic Spectrum disorder (ASD) in mainstream and special class settings
Published 2007“…Active task engagement was found to remain relatively stable and passive task engagement was found to decrease for one child and remain stable for the other. …”
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294
A component analysis of positive behaviour support plans
Published 2012“…Conclusion Only treatment acceptability was found to be related to decreases in behavioural frequency. No single intervention component was found to have a greater association with reductions in challenging behaviour…”
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295
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296
Money and credit policies in small open less-developed economies
Published 1986“…Some of our results were not in line with the analysis in the existing literature because of the differentiating characteristics of the financial markets in the study.…”
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masterThesis -
297
Comparison of the Incidence and Magnitude of Hyponatremia Among Patients With Poststroke Depression Receiving Either Escitalopram or Sertraline
Published 2024“…Selective serotonin reuptake inhibitors (SSRIs) are frequently used as first‐line antidepressants; however, they have been strongly associated with hyponatremia which, in poststroke patients, can worsen outcomes. …”
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298
The Safety of Novel Therapies in Chronic Lymphocytic Leukemia in the Era of Intermittent Fasting: A Pharmacology-Based Review
Published 2024“…Unfortunately, it is unclear whether the associated risks of tumor lysis syndrome (TLS) and gastrointestinal bleeding (GIB) are increased in IF practitioners receiving NAs. This review explored the literature available on the permissibility of IF in CLL patients undergoing treatment with first-line NAs (FLNAs). …”
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299
<i>Haematococcus pluvialis</i> Microalgae Extract Inhibits Proliferation, Invasion, and Induces Apoptosis in Breast Cancer Cells
Published 2022“…In the present study, we investigated the effects of a methanol crude extract called “T1” of <i>H. pulvialis</i> on cell growth and migration/invasion of the BC cell line MDA-MB-231 in comparison to the fibroblast control cells. …”
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300
National Culture and Leadership in the United Arab Emirates (UAE)
Published 2012“…And finally, the study recommends that organisations should hold all the senior executives and line managers accountable for the development of individual managers by owning and executing succession plans.…”
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