Hexokinase-linked glycolytic overload and unscheduled glycolysis in hyperglycemia-induced pathogenesis of insulin resistance, beta-cell glucotoxicity, and diabetic vascular complic... حسب Naila Rabbani (291722)

"…Downstream effector pathways of HK-linked unscheduled glycolysis are mitochondrial dysfunction and increased reactive oxygen species (ROS) formation; activation of hexosamine, protein kinase c, and dicarbonyl stress pathways; and increased Mlx/Mondo A signaling. …"

Assessment of treatment burden and its impact on quality of life in dialysis-dependent and pre-dialysis chronic kidney disease patients حسب Asmaa Al-mansouri (16931739)

"…HD patients experienced significantly higher burden of treatment and lower HR-QOL compared to pre-dialysis patients and that HR-QOL declines as treatment burden increases. Therefore, treatment-related burden should be considered in CKD management and factors that increase it should be considered when designing healthcare interventions directed to CKD patients.…"

Health-related quality of life and its predictors among adults living with HIV/AIDS and receiving antiretroviral therapy in Pakistan حسب Ali Ahmed (2567584)

"…ART has significantly increased the life expectancy of people living with HIV/AIDS (PLWHA). …"

The Relationships between Gender, Life Satisfaction, Loneliness and Problematic Internet Use during COVID-19: Does the Lockdown Matter? حسب Jensen Deutrom (18426978)

"…We examined people’s experiences working from home in the UK to identify risk factors of problematic internet use during the first lockdown period, specifically looking at life satisfaction, loneliness, and gender. A total of 299 adults completed the Problematic Internet Use Questionnaire-Short-Form-6, UCLA-3 Item Loneliness Scale, and Satisfaction with Life Scale online. …"

A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase حسب Ahmed S. Ibrahim (10049522)

Health in times of uncertainty in the eastern Mediterranean region, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 حسب Mokdad, Ali H

"…However, diarrhoeal diseases were the leading cause of death in Somalia (186·7 deaths per 100 000 people) in 2013, which decreased by 26·9% since 1990. …"
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The Combined Effect of Loading Frequency, Temperature, and Stress Level on the Fatigue Life of Asphalt Paving Mixtures Using the IDT Test Configuration حسب Al-Khateeb, Ghazi

"…Findings of the study showed that the increase in loading frequency resulted in an increase in the fatigue life at the two test temperatures 20 and 30C. …"
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Environmental and Economic Life Cycle Analysis of Primary Construction Materials Sourcing Under Geopolitical Uncertainties: A Case Study of Qatar حسب Shaikha Al-Nuaimi (18623737)

"…Based on the results found from the life cycle assessment, an environmental forecast and sensitivity analysis were established. …"

Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic... حسب Muhanad Alhujaily (11630107)

"…This was linked to off-target effects of drugs on glycolysis and was potentiated in hypoxia. …"

Driving toward hydrogen mobility: A life cycle cost analysis of conventional, electric, and hydrogen fuel cell vehicles in Qatar حسب Carlos Méndez (88102)

"…<p dir="ltr">Qatar's transport sector is dominated by the use of personal vehicles, increasing the nation's <u>environmental footprint</u>. …"

A multi-targeted approach to identify potential flavonoids against three targets in the SARS-CoV-2 life cycle حسب Sanjay Kumar (8853)

"…To identify the most promising bioactive flavonoids against the SARS-CoV-2, this article screened a virtual library of 46 bioactive flavonoids against three promising targets in the SARS-CoV-2 life cycle: human TMPRSS2 protein, 3CLpro, and PLpro. …"

Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2... حسب Michael, Brauer

"…For younger demographics (ie, those aged 0–4 years and 5–14 years), risks such as low birthweight and short gestation and unsafe water, sanitation, and handwashing (WaSH) were among the leading risk factors, while for older age groups, metabolic risks such as high SBP, high body-mass index (BMI), high FPG, and high LDL cholesterol had a greater impact. From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20·7% [13·9–27·7]) and environmental and occupational risks (decrease of 22·0% [15·5–28·8]), coupled with a 49·4% (42·3–56·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. …"
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Life Cycle Cost Analysis as a Technique to Reduce Project’s Cost Overruns of Assets in UAE: A Case Study-Based Research حسب El Gergawy, Yahia

"…The qualitative research investigated the current practices in estimating projects life cycle cost at both organisations, and the causes of the cost overruns in their projects life cycle. …"
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Life-threatening abdominal compartment syndrome as a complication of supine super mini percutaneous nephrolithotomy, the first case report and literature review حسب Ibrahim A. khalil (16932498)

"…Although it is a challenging diagnosis and life-threatening condition, morbidity and mortality can be decreased with early detection and drainage of the intra-peritoneal fluid, causing increased abdominal pressure, which is the most important prognostic factor.…"

An investigation into links between UAE STI Policy and the Federal Universities STEM Majors’ Enrolments, Graduates and Research Development: an evidence-based exploration of the im... حسب Khreibi, Rima Abou

"…Zayed University-Dubai had greater STEM majors’ enrolments compared to Zayed University-Abu Dhabi. …"
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Effectiveness of Project Management Office (PMO) in UAE Context: Exploring the Link between Meeting the Critical Success Factors (CSFs) of Central Enterprise PMO and its Added Valu... حسب Fatah, Emad Elsayed Abdel Halim Abdel

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Changing life expectancy in European countries 1990–2021: a subanalysis of causes and risk factors from the Global Burden of Disease Study 2021 حسب Nicholas, Steel

"…The rate of improvement was lower in 2011–19 than in 1990–2011 in all countries except for Norway, where the mean annual increase in life expectancy rose from 0·21 years (95% UI 0·20 to 0·22) in 1990–2011 to 0·23 years (0·21 to 0·26) in 2011–19 (difference of 0·03 years). …"
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COPE for adolescent Syrian refugees in Lebanon: a brief cognitive–behavioral skill-building intervention to improve quality of life and promote positive mental health حسب Doumit, Rita

"…Significant decreases in depression and anxiety, and increases in QOL were also reported. …"
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Which factor explains the life‐history of <i>Xanthium strumarium</i> L., an aggressive alien invasive plant species, along its altitudinal gradient? حسب Rafi Ullah (8146836)

It is not the same green: A comparative LCA study of green hydrogen supply network pathways حسب Dana, Alghool

"…Green hydrogen (H2), a promising clean energy source garnering increasing attention worldwide, can be derived through various pathways, resulting in differing levels of greenhouse gas emissions. …"
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