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A urokinase-activated recombinant diphtheria toxin targeting the granulocyte-macrophage colony-stimulating factor receptor is selectively cytotoxic to human acute myeloid leukemia...
Published 2004“…The activity of this toxin was then tested on a larger group of 13 human AML cell lines; 5 of the 13 cell lines were sensitive to DTU2GMCSF. …”
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Phase transitions of nanoemulsions using ultrasound: Experimental observations
Published 2012“…Additionally, as the size of the emulsion droplet increased, the intensity required for bubble formation decreased. As expected, perfluorohexane emulsions require greater intensity to form cavitating bubbles than perfluoropentane emulsions.…”
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Characterization of the Potency and Mechanism of Action of a Novel Dual-Selective Intermolecularly Complemented Version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Breas...
Published 2023“…Results show that UACC-2087 cell line expresses the three proteases and upon treatment, the levels of expression were not consistent. …”
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Strategie trading company (STC). (c1994)
Published 1994Get full text
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PSA-activated proaerolysin as a prostate specific cancer therapy
Published 2006“…Activity toward proaerolysin was decreased 10-100 fold for each of the proteases tested except PSA, which showed a 4-fold increase in activity against the modified protein. …”
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Deep Learning-Based Fault Diagnosis of Photovoltaic Systems: A Comprehensive Review and Enhancement Prospects
Published 2021“…These faults may affect the different system components such as PV modules, connection lines, converters/inverters, which can lead to a decrease in the efficiency, performance, and further system collapse. …”
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Snake venom in conjugation with silica nanoparticles: an emerging cancer therapy
Published 2025“…<i>In vitro</i> investigations on cancer cell lines revealed a considerable increase in cytotoxicity and induction of apoptosis as compared to free snake venom, with greater selectivity for malignant cells. …”
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Postprandial lipaemia 10 and 34 hours after playing football: Does playing frequency affect the response?
Published 2019“…Performing three consecutive days of football exercise may offer no greater protective effect for postprandial TG before a period of reduced activity, compared to a single session.…”
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Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia
Published 2019“…Curcumin induces apoptosis in B-Pre-ALL cell lines via activation of caspase-8 and truncation of BID. …”
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Water-pipe smoking promotes epithelial–mesenchymal transition and invasion of human breast cancer cells via ERK1/ERK2 pathways
Published 2018“…<p>With the increasing popularity of water-pipe smoking (WPS), it is critical to comprehend how WPS may affect women’s health. …”
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Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF) 1
Published 2015“…PrAgU2/LF was cytotoxic to five out of nine AML cell lines. Cytotoxicity of PrAgU2/LF appeared to be nonapoptotic and was associated with MAPK activation and urokinase activity because all the PrAgU2/LF-sensitive cell lines showed both uPAR expression and high levels of MEK1/2 phosphorylation. …”
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Unsustainability in emergent systems
Published 2017“…In this paper we present a detailed case study of the passenger road transport system in the Greater Beirut Area (GBA) where we identify the root causes of the major problems facing the system today and over the long-term. …”
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Parallel Algorithm for Hardware Implementation of Inverse Halftoning
Published 2005Get full text
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Timing driven genetic algorithm for standard-cell placement
Published 1995Get full text
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