Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF) 1 by Nasser, Selim

“…PrAgU2/LF was cytotoxic to five out of nine AML cell lines. Cytotoxicity of PrAgU2/LF appeared to be nonapoptotic and was associated with MAPK activation and urokinase activity because all the PrAgU2/LF-sensitive cell lines showed both uPAR expression and high levels of MEK1/2 phosphorylation. …”
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A Parallel Algorithm for Inverse Halftoning and its Hardware by Siddiqi, Umair F.

“…Lookup Table (LUT) method for inverse halftoning is computation less, fast and also yields goods results. This paper proposes a parallel algorithm for inverse halftoning by parallelizing the LUT method of inverse halftoning. …”
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Emotional Reactions to Unequal Payment: The Impact of Meritocratic Ideology and Salary Negotiability by Maitner, Angela

“…However, learning that a system is non-negotiable violates expectations associated with meritocratic beliefs, and may therefore increase negative emotion. In two experiments investigating participants’ emotional reactions to payment systems, the more participants endorsed meritocratic ideologies, the less anger they felt when unequal treatment appeared negotiable. …”
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Composite hydrogels from carrageenan-cl-carboxymethyl chitosan–PVA incorporated ZiF-8 as dressing material for wound healing applications by Tooba Yasin (19131382)

“…With increased gel fraction, the increasing ZiF-8 shifted wettability from more hydrophilicity to less hydrophilicity. …”

The chemotherapeutic effect of β-2-himachalen-6-ol in chemically induced skin tumorigenesis by Daaboul, Hamid E.

“…Papilloma yield, volume, histology, and mice weight and liver function were assessed. HC treatment decreased significantly cell survival (IC50 = 7 and IC90 = 40 μg/ml) and increased significantly cells undergoing late apoptosis and necrosis. …”
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Effect of methanolic extract of Quercus infectoria bark on blood lipid profile, glycemia, inflammation, platelet aggregation, ulcer and bacterial activity. (c2005) by Khouzami, Lara

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Editorial: Cancer testis antigens in cancer: Recent developments as cancer biomarkers and therapeutic targets by Adviti Naik (673163)

“…More specifically, they show that silencing of overall SSX expression reduces tumor growth and completely inhibits metastatic burden of lung and liver in vivo. Molecularly, they found that SSX silencing induces cell cycle stalling, increased apoptosis and reduced migration and invasion potential of melanoma cells. …”

Brain and plasma riluzole pharmacokinetics by Milane, Aline

“…The combination was then tested in humans in phase II and phase III studies with less beneficial effects and a faster decline of the disease in the group treated with minocycline. …”
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Cooling Energy and Climate Change Nexus in Arid Climate and the Role of Energy Transition by Ammar M. Khourchid (19420621)

“…The study found that the cooling demand could increase by 13–53% and 19–67% in 2071 and 2100, respectively, with buildings having higher thermal insulation and lower window-to-wall ratio being less affected by climate change. …”

Mitigating undercooling and overheating risk in existing desert schools under current and future climate using validated building simulation model by Mutasim Baba, Fuad

“…Passive winter measures, including high insulation and airtightness level, and using double glass windows, reduce undercooling to less than 40 h but increase overheating to 180 h. …”
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Follow‐Up and Comparative Assessment of SARS‐CoV‐2 IgA, IgG, Neutralizing, and Total Antibody Responses After BNT162b2 or mRNA‐1273 Heterologous Booster Vaccination by Salma Younes (6424865)

“…</p><h3>Results</h3><p dir="ltr">Homologous primary vaccination with ChAdOx1 not only showed less potent NTAb, TAb, anti‐S‐RBD IgG, and anti‐S1 IgA immune responses compared to primary BNT162b2 or mRNA‐1273 vaccination regimens (<i>p</i> < 0.05) but also showed ~3‐fold less anti‐S1 IgA response compared to infection‐induced immunity (<i>p</i> < 0.001). …”

Unsustainability in emergent systems by Haddad, Marc

“…In this paper we present a detailed case study of the passenger road transport system in the Greater Beirut Area (GBA) where we identify the root causes of the major problems facing the system today and over the long-term. …”
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Parallel Algorithm for Hardware Implementation of Inverse Halftoning by Siddiqi, Umair F.

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An adaptive load-balancing approach to XML-based network management using JPVM by Sqalli, M.H.

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Timing driven genetic algorithm for standard-cell placement by Sait, Sadiq M.

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Machine Learning-Based Adaptive Load Balancing Framework for Distributed Object Computing by Helmy, Tarek

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Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways by Shehaby, Wassim N.

“…Flow cytometric analysis indicated that both fractions induced sub-G1 phase accumulation and increased apoptotic cell death. Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. …”
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Enhanced cellular uptake and photochemotherapeutic potential of a lipophilic strained Ru(II) polypyridyl complex by Mehanna, Stephanie

“…When compared to cisplatin, the photoproducts were more potent against all tested cell lines, implying that the complex acquired significant chemotherapeutic potential upon irradiation. …”
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Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance by Ajaz A. Bhat (12984701)

“…<p>Early-stage detection of leukemia is a critical determinant for successful treatment of the disease and can increase the survival rate of leukemia patients. The factors limiting the current screening approaches to leukemia include low sensitivity and specificity, high costs, and a low participation rate. …”

PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications by Pramod Darvin (153341)

“…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …”