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Artificial Intelligence for Detecting and Quantifying Fatty Liver in Ultrasound Images: A Systematic Review
منشور في 2022"…Conclusion: AI-supported systems show potential performance increases in detecting and quantifying steatosis, NASH, and liver fibrosis in NAFLD patients. …"
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Impaired Liver Size and Compromised Neurobehavioral Activity are Elicited by Chitosan Nanoparticles in the Zebrafish Embryo Model
منشور في 2019"…Although no single sign of cardiotoxicity was observed upon exposure to 200 mg/L of ChNPs, as judged by heartbeat rate, the corrected QT interval (QTc, which measures the time between the start of the Q wave and the end of the T wave in the heart's electrical cycle), maximum cardiac arrest, and ejection fraction assays, the same dosage elicited the impairment of both liver size (decreased liver size, but without steatosis and lipid yolk retention) and neurobehavioral activity (increased movement under different light conditions). …"
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Cardiovascular autonomic neuropathy is associated with increased glycemic variability driven by hyperglycemia rather than hypoglycemia in patients with diabetes
منشور في 2023"…ConclusionCAN was associated with increased glycemic variability with less time in euglycemia attributed to a greater time in hyperglycemia but not hypoglycemia.…"
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Cardiovascular autonomic neuropathy is associated with increased glycemic variability driven by hyperglycemia rather than hypoglycemia in patients with diabetes
منشور في 2023"…</p><h3>Conclusion</h3><p dir="ltr">CAN was associated with increased glycemic variability with less time in euglycemia attributed to a greater time in hyperglycemia but not hypoglycemia.…"
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45
Assessment of tropospheric NO<sub>2</sub> concentrations over greater Doha using Sentinel-5 TROPOspheric monitoring instrument (TROPOMI) satellite data: Temporal analysis, 2018–202...
منشور في 2024"…<p dir="ltr">This study presents a temporal evaluation of the tropospheric NO<sub>2</sub> column densities over Greater Doha using TROPOMI satellite data from May 2018 to December 2023, and an assessment of the impact of the preparations and hosting of the FIFA Football World Cup Qatar 2022, on NO<sub>2</sub> levels before, during and after the tournament over Greater Doha. …"
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Effects of lipid administration on liver apoptotic signals in a mouse model of total parenteral nutrition (TPN)
منشور في 2004"…Interestingly, we have recently observed an increase in hepatocyte apoptosis with administration of TPN. …"
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Correction to: Targeted Inactivation of Rin3 Increases Trabecular Bone Mass by Reducing Bone Resorption and Favouring Bone Formation
منشور في 2021"…<p dir="ltr">Correction to: Targeted Inactivation of <i>Rin3</i> Increases Trabecular Bone Mass by Reducing Bone Resorption and Favouring Bone Formation <a href="https://doi.org/10.1007/s00223-021-00827-2" target="_blank">https://doi.org/10.1007/s00223-021-00827-2</a>, published online 16 March 2021.…"
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Efficacy and safety of aldafermin in non-alcoholic steatohepatitis: A systematic review and meta-analysis of randomized controlled trials
منشور في 2024"…<h3>Background</h3><p dir="ltr">Non-alcoholic steatohepatitis (NASH) is an advanced subtype of non-alcoholic fatty liver disease (NAFLD). NASH prevalence is increasing exponentially and carries a high risk for disease progression, cirrhosis, and liver-related mortality. …"
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Novel proteins implicated in lipid metabolism disorders
منشور في 2016"…</p><p>ANGPTL3 is a protein secreted by the liver, belonging to the angiopoietin-like family of eight proteins. …"
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50
Pathology of the liver in obese and diabetic ob/ob and db/db mice fed a standard or high-calorie diet
منشور في 2011"…Non-alcoholic fatty liver disease (NAFLD) is one of the commonest liver diseases in Western countries. …"
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51
Risk factors for early death due to recurrence after liver resection for hepatocellular carcinoma: Results of a multicenter study
منشور في 2004"…Of these, 53 (43%) died of recurrence, 30 (24%) of post-operative complications, and 40 (33%) of liver failure/hemorrhage. On multivariateanalysis, tumor size greater than 5 cm (P < 0.02; odds ratio, 3.0), multiple tumors(P < 0.01; odds ratio, 3.3), and greater than 5 mitoses per 10 high-power fields(P < 0.03; odds ratio, 3) were associated with increased risk of early death due torecurrence.Conclusions: These findings enable identification of patients with HCC who are athigh risk for early death due to recurrence following potentially curative resection whomight be candidates for adjuvant therapy trials.…"
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iPSCs derived from insulin resistant offspring of type 2 diabetic patients show increased oxidative stress and lactate secretion
منشور في 2022"…Clinical studies on first-degree relatives of type 2 diabetic (T2D) patients, which have the highest genetic predisposition to T2D, have given insights into the role of IR in T2D pathogenesis. …"
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Bevacizumab Improves Pathologic Response and Protects Against Hepatic Injury in Patients Treated With Oxaliplatin-Based Chemotherapy for Colorectal Liver Metastases
منشور في 2007"…The current study evaluated the effect of bevacizumab added to fluoropyrimidine-plus-oxaliplatin (5FU/OX) chemotherapy for colorectal liver metastases (CLM) on the pathologic response and nontumorous liver histology. …"
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Anterior ankle impingment syndrome is less frequent, but associated with a longer absence and higher re-injury rate compared to posterior syndrome: a prospective cohort study of 67...
منشور في 2022"…In our study, ankle impingement was the cause of time loss in less than 0.5% of all injuries. PAIS was more frequently reported than AAIS, but AAIS was associated with more absence days and a higher re-injury rate than PAIS. …"
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Sinusoidal obstruction syndrome and nodular regenerative hyperplasia are frequent oxaliplatin-associated liver lesions and partially prevented by bevacizumab in patients with hepat...
منشور في 2010"…Rubbia-Brandt L, Lauwers G Y, Wang H, Majno P E, Tanabe K, Zhu A X, Brezault C, Soubrane O, Abdalla E K, Vauthey J-N, Mentha G & Terris B (2010) Histopathology56, 430–439 Sinusoidal obstruction syndrome and nodular regenerative hyperplasia are frequent oxaliplatin-associated liver lesions and partially prevented by bevacizumab in patients with hepatic colorectal metastasis Aims: Because of its efficacy, oxaliplatin (OX) is increasingly used as a chemotherapeutic agent in the treatment of colorectal liver metastases (CRLM). …"
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Comparative Study on Beneficial Effects of Hydroxytyrosol- and Oleuropein-Rich Olive Leaf Extracts on High-Fat Diet-Induced Lipid Metabolism Disturbance and Liver Injury in Rats
منشور في 2020"…Moreover, these extracts, mainly the hydroxytyrosol-rich extract, reduced the elevated liver enzymes, enhanced the antioxidant status, and attenuated the liver inflammation and apoptosis. …"
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Hepato‐splanchnic fluxes during exercise in patients with cirrhosis—a pilot study
منشور في 2024"…Hepatic glucose output increased from 0.6 (0.5–0.7) to 1.5 (1.3–1.7) mmol/min, while arterial lactate increased from 0.8 (0.7–0.9) to 9.0 (8.1–9.9) mmol/L (<i>P</i> < 0.05) despite a rise in hepatic lactate uptake. …"
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The Superiority of T2*MRI Over Serum Ferritin in the Evaluation of Secondary Iron Overload in a Chronic Kidney Disease Patient: A Case Report
منشور في 2021"…Currently, T2*MRI of the heart and liver is the preferred investigation for evaluating liver iron concentration (LIC) and cardiac iron concentration, which reflect the state of iron overload. …"
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Downregulation of <i>CYP17A1</i> by 20-hydroxyecdysone: plasma progesterone and its vasodilatory properties
منشور في 2022"…Methods: Chimeric mice with humanized liver were treated with 20-hydroxyecdysone for 3 days, and hepatic steroidogenic pathway genes and plasma progesterone were measured by transcriptomics and GC–MS/MS, respectively. …"
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Efficient Detection of Hepatic Steatosis in Ultrasound Images Using Convolutional Neural Networks: A Comparative Study
منشور في 2023"…<h3>Introduction</h3><p dir="ltr">Artificial Intelligence (AI) is widely used in medical studies to interpret imaging data and improve the efficiency of healthcare professionals. Nonalcoholic fatty liver disease (NAFLD) is a common liver abnormality associated with an increased risk of hepatic cirrhosis, hepatocellular carcinoma, and cardiovascular morbidity and mortality. …"