Protein arginine methyltransferase 5 (PRMT5) activates WNT/β‐catenin signalling in breast cancer cells via epigenetic silencing of DKK1 and DKK3 حسب Harshita Shailesh (14779408)

"…<p></p><div> <p>Protein arginine methyltransferase 5 (PRMT5) activity is dysregulated in many aggressive cancers and its enhanced levels are associated with increased tumour growth and survival. However, the role of PRMT5 in breast cancer remains underexplored. …"

Inositol 1,4,5-Trisphosphate Receptors in Hypertension حسب Ali H. Eid (5461829)

"…This involves a phenotypic switch of VSMCs as well as an alteration of cytoplasmic Ca²⁺ signaling machinery, a phenomena tightly related to the aging process. Several lines of evidence implicate changes in expression/function levels of IP₃R isoforms in the development of hypertension, VSMC phenotypic switch, and vascular aging. …"

Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway حسب Kirti.S. Prabhu (17191231)

"…SNG treatment increased Bax/Bcl-2 ratio, which contributed to a leaky mitochondrial membrane leading to cytochrome c release accompanied by caspase activation. …"

A possible culprit for refractory angina حسب Nature Research (16552612)

"…</p><p>This may implicate lipoprotein(a) as having a causal role in refractory angina, but the findings still need to be confirmed by testing a control group of patients who have coronary heart disease but not refractory angina.</p><p>An increased lipoprotein(a) level is known to be highly heritable, and is believed to promote hardening of the arteries by trapping cholesterol in the inner linings of blood vessels, promoting clot formation, recruiting inflammatory cells, or binding pro-inflammatory phospholipids.…"

Development of a multi-zone adiabatic reactor optimization framework for oxidative coupling of methane حسب Murtaza Ali Khan (22804274)

Skopos in Advertising Translation into Arabic حسب Haddad, Khalil

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Structural and Biophysical Characterization of Stable Alpha-Synuclein Oligomers حسب Nishant Vaikath (3554687)

"…It has been reported that the brains of deceased patients with PD contain high levels of protein oligomers that are cross-linked to these aldehydes. Increasing evidence also suggests that prefibrillar oligomeric species are more toxic than the mature amyloid fibrils. …"

Genomic and pleiotropic analyses of resting QT interval identifies novel loci and overlap with atrial electrical disorders حسب Stefan van Duijvenboden (7116386)

"…These findings provide novel insights into how abnormal myocardial repolarization and increased cardiovascular mortality may be linked.</p><p> </p></div><h2>Other Information</h2> <p> Published in: Human Molecular Genetics<br> License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1093/hmg/ddab197" target="_blank">https://dx.doi.org/10.1093/hmg/ddab197</a></p>…"

Assessment of Qatar’s road network under sea-level-rise scenarios using traffic simulation and graph theory حسب Mohammad Zaher Serdar (17191381)

"…High-resolution maps derived from IPCC-AR6 and NOAA projections show that without adaptation measures, SLR may affect approximately 3–11% of land and 2–17% of roads in Qatar, potentially increasing trip durations up to 15 times. Importantly, the estimated impacts are indicative trends rather than definitive outcomes linked to specific emissions scenarios. …"

Treatment of electrolyte disorders in adult patients in the intensive care unit حسب Btaiche, Imad F.

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Governing desalination, managing the brine: A review and systematization of regulatory and socio-technical issues حسب Mohammad Al-Saidi (5751827)

"…<p>Desalination has become an attractive option for addressing water needs or solving problems of increasing water scarcity and short-term supply interruptions. …"

The Obesity Paradox in Cancer, Tumor Immunology, and Immunotherapy: Potential Therapeutic Implications in Triple Negative Breast Cancer حسب Adviti Naik (673163)

"…For instance, obesity has emerged as a risk factor for a dampened anti-tumor immune response and increased risk of immunotherapy-induced immune-related adverse events (irAEs) but has also been linked to improved outcomes with checkpoint blockade. …"

Photobiomodulation: A Systematic Review of the Oncologic Safety of Low-Level Light Therapy for Aesthetic Skin Rejuvenation حسب Graeme Ewan Glass (17733711)

"…<p dir="ltr">Photobiomodulation (PBM) therapy is an increasingly popular modality for aesthetic skin rejuvenation. …"

Diversity of hydrocarbon-degrading bacteria isolated from the rhizosphere of mangrove forests in two coastal regions of Qatar حسب Mona Yousefi (17679490)

"…These variations were reflected in variations in growth, biosurfactant activity, and hydrocarbon degradation capabilities, with differing protein profiles linked to varying hydrocarbon removal efficiencies. …"

Early‐Life Sugar Consumption Affects the Microbiome in Juvenile Mice حسب Reem Moath Alasmar (14778949)

"…<p></p><div> <h3> Scope</h3> <p>The composition of the gut microbiota is influenced by the dietary nutrient. Sugar has been linked with many metabolic health disorders such as heart disease, metabolic syndrome, and immune disorders. …"

The SREBP-dependent regulation of cyclin D1 coordinates cell proliferation and lipid synthesis حسب Arwa Aldaalis (13355328)

"…Consequently, inactivation of SREBP1 in human liver and breast cancer cell lines reduces the expression of cyclin D1 and attenuates Rb phosphorylation. …"

Optimizing microgrid efficiency: Coordinating commercial and residential demand patterns with shared battery energy storage حسب Mohammadreza Gholami (17032317)

"…Moreover, considering DTR for transmission lines, instead of fixed thermal rating, improves the PAR and DPS up to 28.52 % and 41.06 % respectively. …"

Modification and Glycation Microalgae Proteins by Non-Thermal Assisted Process حسب Tahra El Obeid (20487143)

"…Modification techniques applied to plant proteins could be beneficial in enlightening the challenges linked to the digestibility, techno-functional, and sensory attributes of algae proteins. …"

MicroRNAs as Potential Pharmaco-targets in Ischemia-Reperfusion Injury Compounded by Diabetes حسب Hassan Dehaini (14689341)

"…All papers that provided sufficient evidence linking miRNA with I/R, especially in the context of diabetes, were selected. …"

State of the Art in Separation Processes for Alternative Working Fluids in Clean and Efficient Power Generation حسب Odi Fawwaz Alrebei (18288904)

"…Most systems responsible for these undesirable emissions are directly linked to power generation, with gas turbines playing a pivotal role. …"