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121
Characterization of the potency and mechanism of action of a novel dual-selective intermolecularly complemented version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Acute...
منشور في 2023"…However, given that MMP9 was found not to be expressed in the sensitive cell lines, we were able to exclude its expression as a requirement for cytotoxicity. …"
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masterThesis -
122
Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro
منشور في 2016"…The pro-apoptotic effect upon combination of topotecan with andrographolide was further observed using annexin V/PI staining; even though andrographolide alone did not alter cell survival, however, when applied to the cells prior to topotecan treatment, the number of apoptotic cells increased from 16% to 57%. Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…"
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123
Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells
منشور في 2013"…In this study, we target arginine auxotrophy of AML cell lines using human arginase I cobalt-PEG5000. HuArgI(Co)-PEG5000 was cytotoxic to all AML cell lines tested. …"
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124
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125
ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000]
منشور في 2021"…In this study, we examine the mechanism of HuArgI (Co)-PEG5000-induced cell death in both partially and completely auxotrophic GBM cell lines. Our results first showed a significant increase in HuArgI (Co)-PEG5000 treated cells for both U251 and A172 in autophagosome formation; suggesting activation of autophagy in response to arginine deprivation. …"
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masterThesis -
126
The Extent to Which Schools with Mechanistic Structures and their Job Characteristics are Likely to Generate Teachers’ Organisational Commitment: Study Conducted in a Private Schoo...
منشور في 2020"…Staff are motivated due to their perception of the importance of their roles however an increase in autonomy and authority in decision making as well as diversifying the job skills used during teaching could further increase motivation. …"
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127
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128
Artificial neural network algorithms. (c1999)
منشور في 1999احصل على النص الكامل
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masterThesis -
129
Strategies for the production of long-acting therapeutics and efficient drug delivery for cancer treatment
منشور في 2019"…These two techniques improve stability, reduce immunogenicity, and increase drug resistance to proteases. These factors lead to the reduction of injection frequency which increases patient compliance and improve quality of life. …"
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130
Deep aging clocks: AI-powered strategies for biological age estimation
منشور في 2025"…<p>Several strategies have emerged lately in response to the rapid increase in the aging population to enhance health and life span and manage aging challenges. …"
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131
A Survey on the Integration of Blockchain With IoT to Enhance Performance and Eliminate Challenges
منشور في 2021"…It also eases people's daily lives and enhances their interaction with each other as well as with their surroundings and the environment in a broader scope. …"
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132
Computation of Power Extraction From Photovoltaic Arrays Under Various Fault Conditions
منشور في 2020"…It becomes evident from the presented results that optimal reconfiguration of PV arrays can increase the power extraction from PV system with reduced number of P-V peaks. …"
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133
Determinants of female labor force participation: implications for policy in Qatar
منشور في 2022"…The originality of this study lies in its ability to explain how state-directed initiatives can encourage women to participate in the labor market and thus facilitate a rapid increase in the number of employed women in Qatar. …"
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134
Targeting the Folate Receptor: Effects of Conjugating Folic Acid to DOX Loaded Polymeric Micelles
منشور في 2016"…Results show an 80% increase in the accumulation of the antineoplastic agent in the FR+ cell line, when compared to the FR- cell line, thus providing evidence that the efficacy of Pluronic micelles, as drug delivery vehicles, can be enhanced via folic acid targeting.…"
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135
SynergyGrids: blockchain-supported distributed microgrid energy trading
منشور في 2022"…The trading system shows 17.8% decrease in energy cost for consumers and 76.4% decrease in load over utility grids when compared with its counterparts.…"
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136
The effect of daucus carota pentane-diethylether fraction on cancer cells motility and metastasis. (c2013)
منشور في 2013"…Upon treatment, a pronounced decrease in cancer cell motility was observed in the four cell lines used. The treatment also led to a decrease in cancer cell invasion and an increased cell adhesion. …"
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masterThesis -
137
Improving the Performance Measurement Using Overall Equipment Effectiveness (OEE) in Borouge
منشور في 2023"…The main issue found relating to the two extruder production lines productivity was where availability and quality show a significant decrease. …"
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138
Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic...
منشور في 2021"…Spliceosomal gene expression correlated positively with Glo1 in human tumor cell lines and tumors. In clinical chemotherapy of breast cancer, increased expression of Glo1 was associated with decreased patient survival, with hazard ratio (HR) = 1.82 (logrank p < 0.001, n = 683) where upper quartile survival of patients was decreased by 64% with high Glo1 expression.…"
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139
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140
The Impact of a Computerized Potassium Alert on Adverse Drug Events and Pharmacists' Interventions
منشور في 2010"…Methods: An alert was built into the pharmacy computer system, which warned pharmacists about a potassium level greater than 5.1 mEq/L when processing an order that could increase potassium. …"
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