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Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro
Published 2016“…The pro-apoptotic effect upon combination of topotecan with andrographolide was further observed using annexin V/PI staining; even though andrographolide alone did not alter cell survival, however, when applied to the cells prior to topotecan treatment, the number of apoptotic cells increased from 16% to 57%. Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…”
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Congenital agenesis of internal carotid artery with ipsilateral Horner presenting as focal neurological symptoms
Published 2011“…Three types of collateral circulations have been described. These collaterals increase the risk of aneurysm formation and the occurrence of life-threatening subarachnoid hemorrhages. …”
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184
Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells
Published 2013“…In this study, we target arginine auxotrophy of AML cell lines using human arginase I cobalt-PEG5000. HuArgI(Co)-PEG5000 was cytotoxic to all AML cell lines tested. …”
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185
The changing face of Qatar
Published 2015“…This included population size, age distribution, migrant stock, life expectancy, and birth and mortality rates. According to their findings, Qatar's population of 1.87 million represents an 850% increase since 1980, making it the fastest growing population in the GCC countries. …”
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186
ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000]
Published 2021“…In this study, we examine the mechanism of HuArgI (Co)-PEG5000-induced cell death in both partially and completely auxotrophic GBM cell lines. Our results first showed a significant increase in HuArgI (Co)-PEG5000 treated cells for both U251 and A172 in autophagosome formation; suggesting activation of autophagy in response to arginine deprivation. …”
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187
The Extent to Which Schools with Mechanistic Structures and their Job Characteristics are Likely to Generate Teachers’ Organisational Commitment: Study Conducted in a Private Schoo...
Published 2020“…Staff are motivated due to their perception of the importance of their roles however an increase in autonomy and authority in decision making as well as diversifying the job skills used during teaching could further increase motivation. …”
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Artificial neural network algorithms. (c1999)
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190
Targeting the Folate Receptor: Effects of Conjugating Folic Acid to DOX Loaded Polymeric Micelles
Published 2016“…Results show an 80% increase in the accumulation of the antineoplastic agent in the FR+ cell line, when compared to the FR- cell line, thus providing evidence that the efficacy of Pluronic micelles, as drug delivery vehicles, can be enhanced via folic acid targeting.…”
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191
SynergyGrids: blockchain-supported distributed microgrid energy trading
Published 2022“…The trading system shows 17.8% decrease in energy cost for consumers and 76.4% decrease in load over utility grids when compared with its counterparts.…”
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192
The effect of daucus carota pentane-diethylether fraction on cancer cells motility and metastasis. (c2013)
Published 2013“…Upon treatment, a pronounced decrease in cancer cell motility was observed in the four cell lines used. The treatment also led to a decrease in cancer cell invasion and an increased cell adhesion. …”
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193
Improving the Performance Measurement Using Overall Equipment Effectiveness (OEE) in Borouge
Published 2023“…The main issue found relating to the two extruder production lines productivity was where availability and quality show a significant decrease. …”
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194
Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic...
Published 2021“…Spliceosomal gene expression correlated positively with Glo1 in human tumor cell lines and tumors. In clinical chemotherapy of breast cancer, increased expression of Glo1 was associated with decreased patient survival, with hazard ratio (HR) = 1.82 (logrank p < 0.001, n = 683) where upper quartile survival of patients was decreased by 64% with high Glo1 expression.…”
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195
Agent Based Modeling to Optimize Supermarkets Spatial Dimensions
Published 2019“…To improve supermarkets layout from the social aspect, to increase the human comfort and reduce crowding. Despite the supermarket is a major part of our life, but there is one undesirable situation that a lot of people suffer from it, which is crowding. …”
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196
Feasibility Study of a Municipality Solid Waste Incineration Plant in Jordan
Published 1998“…The rapid growth in Jordan’s population coupled with an increasing standard of life, has resulted in a large increase of household and commercial waste. …”
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197
Performance of Different Concrete Types Exposed to Elevated Temperatures: A Review
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198
The Impact of a Computerized Potassium Alert on Adverse Drug Events and Pharmacists' Interventions
Published 2010“…Methods: An alert was built into the pharmacy computer system, which warned pharmacists about a potassium level greater than 5.1 mEq/L when processing an order that could increase potassium. …”
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An investigation into links between UAE STI Policy and the Federal Universities STEM Majors’ Enrolments, Graduates and Research Development: an evidence-based exploration of the im...
Published 2020“…Zayed University-Dubai had greater STEM majors’ enrolments compared to Zayed University-Abu Dhabi. …”
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Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021
Published 2024“…Although the global age-standardised incidence rate of appendicitis has steadily decreased between 1990 and 2021, almost half of GBD regions saw an increase of greater than 10% in their age-standardised incidence rates. …”
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