Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF) 1 by Nasser, Selim

“…PrAgU2/LF was cytotoxic to five out of nine AML cell lines. Cytotoxicity of PrAgU2/LF appeared to be nonapoptotic and was associated with MAPK activation and urokinase activity because all the PrAgU2/LF-sensitive cell lines showed both uPAR expression and high levels of MEK1/2 phosphorylation. …”
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Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia by Shilpa Kuttikrishnan (3520079)

“…Curcumin induces apoptosis in B-Pre-ALL cell lines via activation of caspase-8 and truncation of BID. …”

Water-pipe smoking promotes epithelial–mesenchymal transition and invasion of human breast cancer cells via ERK1/ERK2 pathways by Khaled W. Sadek (14153196)

“…Two breast cancer cell lines, MCF7 and BT20, were used in this investigation. …”

Effect of Surgical Margin Status on Survival and Site of Recurrence After Hepatic Resection for Colorectal Metastases by Pawlik, Timothy

“…Patients with positive margins were more likely to have surgical margin recurrence (P = 0.003). …”
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In search of immune cellular sources of abnormal cytokines in the blood in autism spectrum disorder: A systematic review of case-control studies by Wared Nour-Eldine (13904298)

“…Cytokines IFN-<b>γ</b>, TGF-β, RANTES, and IL-8 were increased in the plasma/serum of subjects with autism, and IFN-<b>γ</b> was likely produced by CD4+ T cells and natural killer (NK) cells, although conflicting evidence is present for IFN-<b>γ</b> and TGF-β. …”

Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018 by Damaris Kinyoki (3458885)

“…Our maps show where large within-country disparities occur, as well as areas likely to fall short of the WHO GNT, offering precision public health tools so that adequate resource allocation and subsequent interventions can be targeted to the most vulnerable populations.…”

Do social responsibility disclosures show improvements on stock price? by Jizi, Mohammad

“…The documented results are likely to encourage banking institutions in the developing countries to invest and report on their social activities. …”
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The effects of attitudes, norms, and perceived control on the adaptation of elderly individuals and individuals with chronic health conditions to heatwaves by Kaddour Mehiriz (3129189)

“…In addition, the results suggest that elderly individuals are less likely than individuals in other age groups to adopt heat protection actions. …”

Microwave-synthesized composite preformed particle gels based on tragacanth gum and palygorskite for high-salinity high-temperature conditions by Ahmed Ben Ali (17792594)

“…Swelling behavior in real Gulf seawater (TDS = 45,2 mg/L) and rheological measurements taken at elevated temperatures (80 °C and 100 °C) showed that the addition of Pal enhanced gel rigidity but slightly reduced swelling capacity, likely due to increased steric hindrance. The formulation TPAC₂ (2.5 g Pal) exhibited an optimal balance between swelling (14.2 g/g at 100 °C) and mechanical strength, making it a strong candidate for reservoir applications. …”

Toward a holistic model of sustainable investment decision-making in SMEs: a structural approach in a developing economy by Dedrix Stephenson Bindeeba (21243596)

“…In contrast, perceptions of regulatory strength and government support do not exhibit signifcant efects, likely due to low enforcement and institutional trust. …”

Treatment with decitabine induces the expression of stemness markers, PD-L1 and NY-ESO-1 in colorectal cancer: potential for combined chemoimmunotherapy by Nassiba Taib (14557385)

“…</p><h2>Methods</h2><p dir="ltr">We compared the effect of DAC in primary 1076 Col and metastatic 1872 Col cell lines isolated and generated from patients’ tumor tissues. …”

The Candida albicans Hwp2 is necessary for proper adhesion, biofilm formation and oxidative stress tolerance by Dimassi, Hani I.

“…It appears that Hwp2 is necessary for proper oxidative stress tolerance, adhesion and biofilm formation as an hwp2 null is more susceptible to increasing doses of hydrogen peroxide, unable to adhere efficiently to epithelial and endothelial cell lines and unable to form wild type biofilm levels.…”
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Exploring the influence of salesperson lone wolf tendencies on customer value co-creation: a social exchange perspective by Itani, Omar S.

“…The findings suggest that salespeople with higher LWTs are more likely to undermine customer trust and escalate conflicts with customers. …”
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Ethnic-specific association of amylase gene copy number with adiposity traits in a large Middle Eastern biobank by Niccolo’ Rossi (14152692)

“…<p>Studies assessing the impact of amylase genes copy number (CN) on adiposity report conflicting findings in different global populations, likely reflecting the impact of ancestral and ethnic-specific environment and lifestyle on selection at the amylase loci. …”

The Prevalence and Genetic Spectrum of Familial Hypercholesterolemia in Qatar Based on Whole Genome Sequencing of 14,000 Subjects by Ilhame Diboun (3522413)

“…We detected 16 known pathogenic/likely pathogenic mutations in LDLR and one in PCSK9; all in a heterozygous state with high penetrance. …”

GERD outcome after bariatric surgery A protocol for systematic review and meta analysis by Abdel-Naser Elzouki (9376853)

“…</p><h3>Conclusion</h3><p dir="ltr">GERD may improve in obese patients who underwent laparoscopic sleeve gastrectomy (LSG); however, the most favorable effect is likely to be found after Roux-en-Y gastric bypass surgery. …”

Ab initio molecular dynamics study of the interlayer and micropore structure of aqueous montmorillonite clays by James L. Suter (1369596)

“…Acid treated clays are likely to have both sites protonated. The (010) surface does not have the same interfacial hydrogen bonding structure; it is much less stable and we observe dissociation of half the terminal SiOH groups (SiOH→ SiO− +H+) in our models. …”

The role of microRNAs in skin cancers by Nature Research (16552612)

“…<p>Skin cancer is a growing public health problem around the world, largely due to an aging population and increased exposure to ultraviolet radiation in sunlight, which causes more than 90% of all cases. …”

TEACHERS’ PERSPECTIVE ON ENGAGED TEACHING: STUDY FROM AN AMERICAN CURRICULUM ELEMENTARY SCHOOL IN DUBAI by ALBASHA, WAFA

“…Special emphasis was placed on schools in UAE and specifically in Dubai, where there has been an increasing number of American curriculum schools. Using mixed methodology, the researcher obtained the teachers’ perspective to help identify learner’s difficulties when responding to class activities and the likely impact on their learning experiences. …”
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Forecasting Resilience Loss for Flexible Pavement under the Impact of Temperature due to Climate Change by ALARYANI, MOHAMMED MUFTAH

“…The HDM-4 model, which is extensively used in pavement management systems, does not utilise future climate predictions. Climate change is likely to threaten pavement infrastructures’ resilience through extreme weather events and chronically through gradual degradation. …”
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