Dynamic Biomarkers of Response to Anti-Immune Checkpoint Inhibitors in Cancer حسب Said Dermime (79420)

"…To date, immune check-point inhibitors have been approved as first or second line therapy options in a broadening range of metastatic cancer and increasingly explored in the treatment of early stage tumors. …"

PD-L1 Blockade by Atezolizumab Downregulates Signaling Pathways Associated with Tumor Growth, Metastasis, and Hypoxia in Human Triple Negative Breast Cancer حسب Reem Saleh (3513056)

"…In this study, we investigated the molecular mechanisms by which the human TNBC cell line MDA-MB-231, expressing PD-L1, responds to atezolizumab, using RNA-Seq. …"

Prevalence and global trends of polypharmacy in patients with chronic kidney disease: A systematic review and meta-analysis حسب Lina Naseralallah (14146465)

"…In line with the therapeutic guidelines, managing CKD and its complications necessitates prescribing multiple medications, which predisposes patients to polypharmacy. …"

Need for Affect, Problematic Social Media Use and the Mediating Role of Fear of Missing Out in European and Arab Samples حسب Areej Babiker (17032314)

"…<h3>Purpose </h3><p dir="ltr">The growing awareness and concern about the excessive use of social media have led to an increasing number of studies investigating the underlying factors contributing to this behavior. …"

A Model of Telecommunication Sector Development and Economical Growth in GCC Countries: A Case Study of UAE حسب Amiri, Shaima Yousef

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The impact of cultural diversity on project management communication حسب HUSSEIN, ALAA BASSAM FUAD

"…The results of the study are in line with some previous research, who said that when examined in terms of age, gender, and ethnicity, having a diverse workforce has a positive impact on the organization's performance. …"
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The synthetic cathinones MDPHP and MDPV: Comparison of the acute effects in mice, in silico ADMET profiles and clinical reports حسب Marta, Bassi

"…Our results substantiated that MDPHP and MDPV similarly affect sensorimotor and behavioural responses in mice, importantly increased locomotion and induced aggressive behaviour, and, at higher dosage, increased heart rate and blood pressure. …"
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Spatial and temporal assessment of metal pollution in the sediments of the Qaraoun reservoir, Lebanon حسب Wazne, Mahmoud

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Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1⁺/NKX6.1⁺ progenitors حسب Noura Aldous (15429873)

"…Furthermore, RFX6 deficiency resulted in the formation of smaller islet organoids due to increased cellular apoptosis, linked to reduced catalase expression, implying a protective role for RFX6. …"

The Human Microbiome in Chronic Kidney Disease: A Double-Edged Sword حسب Eman Wehedy (13275305)

"…Fluctuations in the urinary microbiome are linked to increased susceptibility to infection and antibiotic resistance. …"

Using Nearpod to Promote Engagement in Online ESL Classes: A Mixed-Methods Study in the Context of Higher Education حسب Alawadhi, Azza

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Assessment of High-resolution Local Emissions and Land-use in Air Quality Forecasting at an Urban, Coastal, Desert Environment حسب Christos Fountoukis (4722963)

"…The model’s forecast accuracy was assessed against measurement data from five ground air quality monitoring stations in the greater metropolitan area of Doha over a one-month period. …"

The Effects of Online Formative and Summative Assessment on Test Anxiety and Performance: A Study Among First-Year Undergraduate Students at A Higher Education Institution in Abu D... حسب ALSUWAIDI, MUNA

"…The presented study was conducted to provide greater insight into the potential positive, neutral and/or negative effects of online formative and summative assessment on test anxiety and performance. …"
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PDX1⁻/NKX6.1⁺ progenitors derived from human pluripotent stem cells as a novel source of insulin‐secreting cells حسب Bushra Memon (4792767)

"…</p><h3>Materials and Methods</h3><p dir="ltr">Three different hPSC lines were differentiated into PDX1⁻/NKX6.1⁺ progenitors, which were further differentiated into insulin-secreting cells using two different protocols. …"

Indirect tool-wear maps for tool condition monitoring in dry metal drilling operations حسب Ammouri, A.H.

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DLC2/StarD13 plays a role of a tumor suppressor in astrocytoma حسب El-Sitt, Sally

"…Finally, we detected an increase in p-ERK in StarD13 knockdown cells, uncovering a potential link between Rho GTPases and ERK activation.…"
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Flavin Adenine Dinucleotide (FAD) and Pyridoxal 5′-Phosphate (PLP) Bind to Sox9 and Alter the Expression of Key Pancreatic Progenitor Transcription Factors حسب Zeyaul Islam (5867387)

"…Previously, there was no known link between FAD, PLP, or other co-factors and Sox9 for function. …"

Digital wellbeing tools through users lens حسب Mohamed Basel Almourad (17150983)

"…One strategy to help regulate digital usage and, potentially, increase digital wellbeing is to devise smartphone applications to collect data about usage and increase users' awareness of it and enable them to set limits and alert users accordingly. …"

ACTB Loss-of-Function Mutations Result in a Pleiotropic Developmental Disorder حسب Sara Cuvertino (18892069)

"…<i>ACTB</i> mRNA expression levels in lymphoblastic lines and fibroblasts derived from affected individuals were decreased in comparison to those in control cells. …"

Expanding the donor pool حسب Ramos, Emilio

"…In 1990, one-year graft survival rates were about 70%; by 2000, they were greater than 90% (United States Renal Data System, 2001). …"
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