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381
Dynamic Biomarkers of Response to Anti-Immune Checkpoint Inhibitors in Cancer
منشور في 2021"…To date, immune check-point inhibitors have been approved as first or second line therapy options in a broadening range of metastatic cancer and increasingly explored in the treatment of early stage tumors. …"
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382
PD-L1 Blockade by Atezolizumab Downregulates Signaling Pathways Associated with Tumor Growth, Metastasis, and Hypoxia in Human Triple Negative Breast Cancer
منشور في 2019"…In this study, we investigated the molecular mechanisms by which the human TNBC cell line MDA-MB-231, expressing PD-L1, responds to atezolizumab, using RNA-Seq. …"
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383
Prevalence and global trends of polypharmacy in patients with chronic kidney disease: A systematic review and meta-analysis
منشور في 2023"…In line with the therapeutic guidelines, managing CKD and its complications necessitates prescribing multiple medications, which predisposes patients to polypharmacy. …"
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384
Need for Affect, Problematic Social Media Use and the Mediating Role of Fear of Missing Out in European and Arab Samples
منشور في 2023"…<h3>Purpose </h3><p dir="ltr">The growing awareness and concern about the excessive use of social media have led to an increasing number of studies investigating the underlying factors contributing to this behavior. …"
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385
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386
The impact of cultural diversity on project management communication
منشور في 2022"…The results of the study are in line with some previous research, who said that when examined in terms of age, gender, and ethnicity, having a diverse workforce has a positive impact on the organization's performance. …"
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387
Effects of selenium in comparison to exendin-4 on the expression of GLP-1R, IRS-1 and preproinsulin in the pancreas of diabetic rats
منشور في 2016"…It binds and activates GLP-1R with greater potency than GLP-1 and is used in the treatment of diabetes mellitus. …"
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article -
388
Epidemiological and clinical characteristics of fall-related injuries: a retrospective study
منشور في 2020"…Although the rate of fall-related injuries decreased over the years, the average number of patients per year remained high accounting for 32% of the hospitalized patients with moderate to severe injuries. …"
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389
Trends in criminal convictions in Japan for vehicle collisions where one driver suffers from an epileptic seizure
منشور في 2015"…To reduce collisions to an even greater degree, this type of collision should be prevented. …"
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390
The synthetic cathinones MDPHP and MDPV: Comparison of the acute effects in mice, in silico ADMET profiles and clinical reports
منشور في 2024"…Our results substantiated that MDPHP and MDPV similarly affect sensorimotor and behavioural responses in mice, importantly increased locomotion and induced aggressive behaviour, and, at higher dosage, increased heart rate and blood pressure. …"
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article -
391
Efficient and cost-effective alternative treatment for recurrent urinary tract infections and interstitial cystitis in women
منشور في 2016"…UTIs are primarily caused by Escherichia coli, which increases the likelihood of a recurrent infection. …"
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article -
392
Narratives of internal migration experiences, health/well-being issues among females working as head-porters (Kayayei) in Ghana
منشور في 2020"…They also suggest that the Kayayei phenomenon is a significant child protection, health/well-being concern yet to be given adequate attention in ways that consider the implications of such large internal migration of females on the overall humanresourcedevelopmentcapacitiesofruralcommunities. …"
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393
A discrete-time stochastic iterative learning control algorithm for a class of nonlinear systems
منشور في 2005"…The author also shows that in presence of measurement noise, the state error covariance matrix converges to zero as the number of learning iterations increases. Finally, a numerical example is given that compares the performance of the proposed algorithm to a conventional ILC algorithm.…"
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article -
394
Design of a vibration absorber for harmonically forced damped systems
منشور في 2013"…The optimal absorber parameters are obtained with the aim of minimizing the maximum of the primary system frequency response. For a given damping ratio of the primary system and mass ratio of the system, the optimal stiffness and damping ratios of the absorber are calculated numerically. …"
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article -
395
Students’ conceptual understanding of a function and its derivative in an experimental calculus course
منشور في 2005"…Calculus has been witnessing fundamental changes in its curriculum, with an increased emphasis on visualization. This mode for representing mathematical concepts is gaining more strength due to the advances in computer technology and the development of dynamical mathematical software. …"
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article -
396
Exogenous Endophthalmitis in Diabetic Patients
منشور في 2012"…Diabetes mellitus is a systemic disease that increases the risk of infections. Exogenous endophthalmitis is an inflammatory disease to which diabetic patients are more predisposed to than nondiabetic patients undergoing any intraocular intervention. …"
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article -
397
Teachers’ and Management Personnel’s Perceptions of The Impact of Classroom Setting on Students’ Motivation to Read
منشور في 2020"…When evaluating the classroom learning environment, little attention is given to the classroom physical setting and the way it affects how students perceive their learning environment. …"
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masterThesis -
398
Glucose excursions in type 2 diabetes modulate amyloid-related proteins associated with dementia
منشور في 2021"…Dementia is a recognized complication of type 2 diabetes (T2D) with an increasing prevalence, and AD is the most common cause. …"
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399
An Investigative Study into the Socialization and Learning of Children at a Preschool in Dubai, U.A.E. and the Parental Demographic Factors that may Contribute to it
منشور في 2012"…It can therefore be inferred that there is low participation and low quality of pre-schooling if compared to powerful knowledge economies, and given the fact that these important years form the foundation of later achievements for the young child, it is imperative that all stake holders and most importantly the government must introduce positive change and reforms and more importantly implement them effectively by increasing participation in this sector.…"
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400
Vitamin D Association With Macrophage-Derived Cytokines in Polycystic Ovary Syndrome: An Enhanced Risk of COVID-19 Infection?
منشور في 2021"…Vitamin D deficiency was associated with decreased CD80 and IFN-γ in PCOS and IL-12 in both groups (p<0.05). …"