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581
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582
Thymoquinone from Nigella sativa seeds promotes the antitumor activity of noncytotoxic doses of topotecan in human colorectal cancer cells in vitro
Published 2016“…In conclusion, thymoquinone increased the effectiveness of the chemotherapeutic reagent topotecan by inhibiting proliferation and lowering toxicity through p53- and Bax/Bcl2-independent mechanisms.…”
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583
Sentiment analysis for Arabizi in social media. (c2015)
Published 2015“…With the vast increase of social media users over the past few years, millions of product reviews are discussed and posted in online forums and social media such as Facebook and Twitter. …”
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masterThesis -
584
Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021
Published 2024“…Although the global age-standardised incidence rate of appendicitis has steadily decreased between 1990 and 2021, almost half of GBD regions saw an increase of greater than 10% in their age-standardised incidence rates. …”
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585
Perinatal exposure to PFOS and sustained high-fat diet promote neurodevelopmental disorders via genomic reprogramming of pathways associated with neuromotor development
Published 2024“…We found that female mice exposed to PFOS alone showed an increase in weight, while HFD expectedly increased body weight. …”
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586
Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes
Published 2023“…Three DNAJB3 knockout (KO) lines were generated (KO 30, 44 and 47), using CRISPR-Cas9. …”
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587
Characterization of the potency and mechanism of action of a novel dual-selective intermolecularly complemented version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Acute...
Published 2023“…However, given that MMP9 was found not to be expressed in the sensitive cell lines, we were able to exclude its expression as a requirement for cytotoxicity. …”
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masterThesis -
588
The anticancer effect of β-2 himachalen-6-ol from Lebanese wild carrot on human acute myeloid leukemia cells. (c2016)
Published 2016“…Daucus carota oil extract was subjected to silica gel column chromatography in order to isolate the major compound β-2-himachalen-6-ol and test its anticancer activity against five AML cell lines: Mono-Mac-1, HL60, KG1, ML2, and U937. Results revealed that the chemical composition of the Lebanese DCOE varied drastically among different plant parts and between different locations. …”
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masterThesis -
589
BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells
Published 2020“…</p><h3>Methods</h3><p dir="ltr">Breast cancer cell lines with different molecular subtypes (MDA-MB-231, MCF7, and SKBR-3) were treated with different concentrations of VCX for indicated time points. …”
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590
The Effects of Social Determinants of Health on Cardiovascular Outcomes in Lebanese with Type 2 Diabetes
Published 2020“…Background: Type 2 Diabetes Mellitus (T2DM) is one of the most prevalent chronic diseases in Lebanon and is known to increase the risks of cardio-metabolic events. Diabetes self-management is essential for glycemic control and prevention of cardiovascular complications. …”
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masterThesis -
591
Prostaglandin E2 stimulates p53 transactivational activity through specific serine 15 phosphorylation in human synovial fibroblasts ROLE IN SUPPRESSION OF c/EBP/NF-κB-MEDIATED MEKK...
Published 2006“…Cyclooxygenase-2 (COX-2) overexpression has been linked to cell survival, transformation, and hyperproliferation. …”
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592
RFX3 is essential for the generation of functional human pancreatic islets from stem cells
Published 2025“…</p><h3>Methods</h3><p dir="ltr">We generated <i>RFX3 </i> knockout (<i>RFX3 KO</i>) iPSC lines using CRISPR/Cas9 and differentiated them into pancreatic islet organoids. …”
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593
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594
A nonlinear PID servo controller for computer hard disk drives
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595
Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal
Published 2019“…Proteins susceptible to MG modification were enriched in protein folding, protein synthesis, serine/threonine kinase signalling, glycolysis and gluconeogenesis. MG was increased in high glucose by increased flux of MG formation linked to increased glucose metabolism mediated by proteolytic stabilisation and increase of hexokinase-2 (HK-2); later potentiated by proteolytic down regulation of glyoxalase 1 (Glo1) - the major enzyme of MG metabolism. …”
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596
The Association Between Estrogen‐Containing Oral Contraceptive Pills and Hypothyroidism
Published 2025“…These findings highlight the need for further research to explore the mechanisms linking OCP use to thyroid dysfunction and to investigate other potential risk factors.…”
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597
Corrosion Inhibition of Mild Steel in 2M HCl Using Aqueous Extract of Eggplant Peel
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598
Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer
Published 2025“…Silencing LDHC in breast cancer cell lines (MDA-MB-468, BT-549, HCC-1954) enhanced early T cell activation and cytolytic activity. …”
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599
G9a-mediated repression of CDH10 in hypoxia enhances breast tumour cell motility and associates with poor survival outcome
Published 2020“…CDH10 overexpression significantly reduces cellular movements in breast cancer cell lines and prevents the hypoxia-mediated increase in cell motility. …”
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600
The relationship between Determinants of Risk Governance assurance and efficacy of the Public projects in the Government of Dubai from the perspective of Internal Audit Function
Published 2018“…These mega-projects may include the construction of major buildings, roads, railway lines and airports. The success of these public initiatives may create the course for the government to decrease its reliance on other sectors. …”
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