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301
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
منشور في 2019"…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …"
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302
Hydrophobic Ionic Liquids for Efficient Extraction of Oil from Produced Water
منشور في 2022"…The extraction efficiency was found to increase with increasing cation alkyl chain length from C2 to C10. …"
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303
Incidence of Sedation-Related Complications With Propofol Use During Advanced Endoscopic Procedures
منشور في 2010"…We performed a regression analysis to compare characteristics of patients requiring AMs (AM+) with those who did not (AM−). Results A total of 799 patients were enrolled over 7 months. …"
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304
The Prevalence and Genetic Spectrum of Familial Hypercholesterolemia in Qatar Based on Whole Genome Sequencing of 14,000 Subjects
منشور في 2022"…In this study, we combined whole-genome sequencing data from the Qatar Genome Program with deep phenotype data from Qatar Biobank for 14,056 subjects to determine the genetic spectrum and estimate the prevalence of FH in Qatar. …"
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305
Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres
منشور في 2024"…Cytotoxicity assays on human cell lines showed no toxicity towards cells at concentrations of up to 100 µg ml−1 but exhibited increased toxicity at concentrations exceeding 1000 µg ml−1. …"
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306
Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases
منشور في 2010"…For example, a few years ago an extrahepatic metastasis effectively eliminated surgical resection, but a combination of chemotherapeutic options and surgical techniques has expanded the indications for resection and increased the population of patients who may benefit.1,2 Neoadjuvant chemotherapy has increased the resectability rate by 11% to 37%.1 Unfortunately, greater than 80% of patients undergoing hepatic resection will have recurrences, mostly within the first 2 years.2 Nonetheless, the only hope for cure is resection, and prior surgical dogma based on the number of lesions, size of the tumor-free resection margin, and presence of resectable extrahepatic disease must be questioned.3- 5 The current standard approach to surgical planning is contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI) for specific tumor characteristics or contraindications to CT.6 Several series showed that focal extrahepatic disease, an isolated pulmonary lesion, can be safely resected, with 5-year survival rates of 29% to 58%.7,8 In 1 series,7 17 of 30 patients required 3 or more resections. …"
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307
Spatial modelling of contribution of individual level risk factors for mortality from Middle East respiratory syndrome coronavirus in the Arabian Peninsula
منشور في 2017"…The odds of dying from the disease was found to increase as age increased beyond 25 years and was much higher for individuals with any underlying comorbidities.…"
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308
Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans
منشور في 2024"…In addition to cell lines, we assessed the impact of BTZ in an in vivo setting using Caenorhabditis elegans (C. elegans). …"
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309
Open access of evidence‐based publications
منشور في 2015"…We demonstrated that despite a 10‐fold increase in the number of evidence‐based publications in the past 10 years, the rate of free systematic reviews in the general biomedical literature did not change for the last two decades. …"
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310
Teaching the novel in a university english as a foreign language (EFL) context
منشور في 2016"…The aim of the present study is to explore the preliminary  effect of selected novels combined with film and student oral presentations on L1 Arabic EFL learners  use of vocabulary in one 20th Century American Novel course at an English medium university in Lebanon. Two literary essay tests were administered to 25 students, one at the beginning and another at the end of the semester, holistically scored and qualitatively analyzed for vocabulary variety. Main findings indicated that although the holistic scores did not significantly increase, there was use of a more diverse and use of vocabulary on Test 2. Recommendations are made for classroom practice and future research.…"
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311
The Impact Of E-Leadership On Employees
منشور في 2023"…Work-from-home became an increasingly common business practice and company offices increasingly became unoccupied. …"
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masterThesis -
312
Modulation of Chronic Stress Outcomes by Dietary Sweeteners: A Comparative Study of Sucrose and Aspartame in Mice
منشور في 2025"…In contrast, aspartame did not appear to mitigate behavioral effects of stress. …"
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masterThesis -
313
Thermal Properties of TiO2NP/CNT/LDPE Hybrid Nanocomposite Films
منشور في 2018"…The TONP incorporation did not modify the Xc %. Moreover, thermal gravimetric analysis (TGA) thermograms confirmed the increased thermal stability after introducing CNTs and hybrid fillers compared to TONP incorporation.…"
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314
Comparative Evaluation of Membrane Filtration on the Tertiary Treatment of Synthetic Secondary Effluent
منشور في 2022"…Moreover, as pressure increased there was a slight increase in the efficiency. …"
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315
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316
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317
Suspicious Behavior Detection with Temporal Feature Extraction and Time-Series Classification for Shoplifting Crime Prevention
منشور في 2023"…The rise in crime rates in many parts of the world, coupled with advancements in computer vision, has increased the need for automated crime detection services. …"
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318
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319
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320
The distribution of toxic sources in Louisiana
منشور في 1993"…Furthermore, the greater the percentage of blacks in a community, the greater the reductions in discharges. …"
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masterThesis