Targeting Breast Cancer Using Hyaluronic Acid-Conjugated Liposomes Triggered with Ultrasound حسب Ben-Daya, Mohamed

"…HA conjugation to the liposomes resulted in a significant increase in calcein uptake by the breast cancer cell line MDA-MB-231 known for its CD44 (HA receptor) overexpression, while such an effect was not recorded with NIH-3T3, an embryonic mouse fibroblast, with low levels of CD44 expression. …"
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Photoactivatable RuII Complex Bearing 2,9‐Diphenyl‐1,10‐phenanthroline: Unusual Photochemistry and Significant Potency on Cisplatin‐Resistant Cell Lines حسب Mansour, Najwa

"…In conclusion, the Ru‐centered complex 1 could represent a potential photoactivatable chemotherapeutic drug that increases selectivity to tumors and offers alternative treatment in the light of increasing cisplatin resistance.…"
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Fluid Administration in Emergency Room Limited by Lung Ultrasound in Patients with Sepsis: Protocol for a Prospective Phase II Multicenter Randomized Controlled Trial حسب Mouhand F H Mohamed (20318412)

"…Thus, B lines seen by bedside ultrasound may have a role in guiding fluid therapy.…"

The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... حسب Wesal Habbab (17346961)

"…In this study we recorded maximum increase in total PP2A at 3 µM sodium selenate in a neuron cell line. …"

Wastewater reuse for livestock feed irrigation as a sustainable practice: A socio-environmental-economic review حسب Fatima-Zahra Lahlou (16931766)

Is board compensation excessive? حسب Dah, Mustafa A.

"…For companies that overpay, the average excess compensation is greater than $60,000 per director, while directors that are underpaid receive about $33,000 less than predicted. …"
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Evidence-based safety education and training for traffic injury prevention حسب Abbas Motevalian (338825)

"…Bicycle skill training for children and youth may increase their safety knowledge, but not necessarily improve their behavior or decrease their injury rates. …"

"Development of Authentic Annual and Seasonal Lightning Thunderstorms Day Maps for Saudi Arabia" حسب Shwehdi, M. H.

"…The southern region in general, and especially the cities of Abha, Taif and Al-Baha, has shown greater numbers of thunderstorm days all year round. …"
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"Thunderstorm distribution and frequency in Saudi Arabia" حسب Shwehdi, M. H.

"…The southern region in general, and especially the cities of Abha, Taif and Al-Baha, has shown greater numbers of thunderstorm days all year round. …"
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Visitors off the trail: Impacts on the dominant plant, bryophyte and lichen species in alpine heath vegetation in sub-arctic Sweden حسب Monika, Rawat

"…With a greater decrease in taller forbs and shrubs than in graminoids and prostrate plants, a greater decrease in lichen than in bryophyte species, and a change in vegetation composition. …"
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Modulation of SLFN11 induces changes in DNA Damage response in breast cancer حسب Christophe Michel Raynaud (17449906)

"…</p><h3>Conclusion</h3><p dir="ltr">To our knowledge this is the first report of the stable non-lethal increase of SLFN11 expression in a cancer cell line. …"

Malva pseudolavatera Leaf Extract Promotes ROS Induction Leading to Apoptosis in Acute Myeloid Leukemia Cells in Vitro حسب El Khoury, Marianne

"…Treatment of AML cell lines with M. pseudolavatera methanolic leaf extract showed a dose- and time-dependent inhibition of proliferation and a dose-dependent increase in apoptotic hallmarks such as an increase in phosphatidylserine on the outer membrane leaflet and membrane leakage in addition to DNA fragmentation. …"
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Dual Targeting of Matrix Metalloproteases and the MAPK Pathway in Acute Myeloid Leukemia Cells Using an MMP-activated anthrax lethal toxin (PrAgL1/LF) حسب Al Saneh, Ahmad

"…Our results demonstrate that vertical inhibition does offer increased potency in comparison to single targeting of the MAPK pathway when working with sensitive cell lines that are dependent on the cascade. …"
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Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro حسب Rizk, Sandra

"…However, due to its dose-limiting cytotoxicity, combination treatments have been investigated to achieve better outcome with less side effects. Andrographolide (AG) is a plant-derived compound that was reported to induce apoptosis and autophagy in acute myeloid leukemia cell lines. …"
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Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017) حسب Khalil, Nathalie

"…It is also important to mention that we noticed an increase in the percent of surviving cells among completely auxotrophic cell lines postaddition of citrulline at 72, 96 and 120 hours of drug incubation. …"
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Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells حسب Haykal, Tony

"…Treatment with an A. cherimola seed ethanolic extract promotes a dose- and time-dependent inhibition of the proliferation of various AML cell lines, but not MSCs. Positive Annexin V staining, as well as DNA fragmentation, confirm an increase in apoptotic cell death by upregulating the expression of pro-apoptotic proteins which control both intrinsic and extrinsic pathways of apoptosis. …"
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Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells By Peter Nasr A thesis حسب Nasr, Peter

"…Treatment with an A. cherimola seed ethanolic extract promotes a dose- and time-dependent inhibition of the proliferation of various AML cell lines, but not MSCs. Positive Annexin V staining, as well as DNA fragmentation, confirm an increase in apoptotic cell death by upregulating the expression of pro-apoptotic proteins which control both intrinsic and extrinsic pathways of apoptosis. …"
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A urokinase-activated recombinant diphtheria toxin targeting the granulocyte-macrophage colony-stimulating factor receptor is selectively cytotoxic to human acute myeloid leukemia... حسب Abi-Habib, Ralph J.

"…The activity of this toxin was then tested on a larger group of 13 human AML cell lines; 5 of the 13 cell lines were sensitive to DTU2GMCSF. …"
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Malva pseudolavatera Leaf Extract Promotes ROS Induction Leading to Apoptosis in Acute Myeloid Leukemia Cells In Vitro حسب El Khoury, Marianne

"…Treatment of AML cell lines with M. pseudolavatera methanolic leaf extract showed a dose- and time-dependent inhibition of proliferation and a dose-dependent increase in apoptotic hallmarks such as an increase in phosphatidylserine on the outer membrane leaflet and membrane leakage in addition to DNA fragmentation. …"
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Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes حسب Maryam Aghadi (17128819)

"…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …"