Identification of Cancer Stem Cells in Human Gastrointestinal Carcinoid and Neuroendocrine Tumors حسب Gaur, Puja

"…We sought to identify gastrointestinal neuroendocrine CSCs (N-CSCs) in surgical specimens and a NET cell line and to characterize novel N-CSC therapeutic targets. …"
احصل على النص الكامل
احصل على النص الكامل

Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway حسب Shilpa Kuttikrishnan (3520079)

"…Our study investigated NSP‐B's antitumor effects on MM cell lines (U266 and RPMI8226) and the involved molecular mechanisms. …"

Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells <i>via</i> Tryptophan 2,3 Dioxygenase حسب Marta Cecchi (21363581)

"…Moreover, dex stimulates spherogenesis of both cell lines, which is mediated by TDO, evident by its suppression with 680C91, a TDO inhibitor. …"

Evaluation of Estrone Liposomes using Microfluidics for Breast Cancer Therapy حسب Al Bostami, Rouba D.

احصل على النص الكامل

Effects of natural organic matter on aggregation kinetics of boron nanoparticles in monovalent and divalent electrolytes حسب Liu, Xuyang

"…However, the attachment efficiency kept increasing in the presence of CaCl2 and alginate with the increase in the electrolyte concentration and was greater than unity at >4 mM CaCl2. The destabilization was attributed to bridging of the nanoparticles by the alginate–Ca2+ system. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Optimum sizing of steam turbines for concentrated solar power plants حسب Poullikkas, Andreas

"…Finally, although the cost of electricity of a CSP plant with capacities greater than 1MWe is significantly reduced to less than 1US$/kWh, currently such technology can only become economically viable through supporting schemes.…"
احصل على النص الكامل

The impact of green supply chain management practices on environmental performance during COVID-19 period: the case of discretionary companies in the G-20 countries حسب El Khoury, Rim

"…It highlights the impact of green initiatives to cope with major disruptions and decrease pollution and environmental disaster.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

A control algorithm to increase the efficient operation of wind energy conversion systems under extreme wind conditions حسب Nyam Jargalsaikhan (17380429)

"…<p dir="ltr">This paper aims to increase the power production of gearless permanent magnet synchronous generator (PMSG) based wind energy conversion systems (WECS) in strong (greater than 25 m/s) wind speed regions. In general, most wind turbines cut off when wind speed is over the cut-out rate; as a result, the power generation of the wind farm decreases. …"

A novel inhibitor of STAT3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells حسب Abou-Ghazal, Mohamed K.

"…Results WP1066 achieved an IC50 of 1.6 μM, 2.3 μM, and 1.5 μM against melanoma cell line A375, B16 and B16EGFRvIII, respectively. WP1066 suppressed the phosphorylation of JAK2 and STAT3 (Tyr705) in these cells. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T ce... حسب Abou-Ghazal, Mohamed

"…Experimental Design: The antitumor activities and related mechanisms of WP1066 were investigated both in vitro on melanoma cell lines and in vivo on mice with subcutaneously syngeneic melanoma or with intracerebral melanoma tumors. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation حسب Shilpa Kuttikrishnan (3520079)

"…Prist significantly increases reactive oxygen species (ROS) levels and depletes glutathione (GSH), leading to mitochondrial dysfunction and cytochrome c release. …"

Protein arginine methyltransferase 5 (PRMT5) activates WNT/β‐catenin signalling in breast cancer cells via epigenetic silencing of DKK1 and DKK3 حسب Harshita Shailesh (14779408)

"…<p></p><div> <p>Protein arginine methyltransferase 5 (PRMT5) activity is dysregulated in many aggressive cancers and its enhanced levels are associated with increased tumour growth and survival. However, the role of PRMT5 in breast cancer remains underexplored. …"

Inositol 1,4,5-Trisphosphate Receptors in Hypertension حسب Ali H. Eid (5461829)

"…This involves a phenotypic switch of VSMCs as well as an alteration of cytoplasmic Ca²⁺ signaling machinery, a phenomena tightly related to the aging process. Several lines of evidence implicate changes in expression/function levels of IP₃R isoforms in the development of hypertension, VSMC phenotypic switch, and vascular aging. …"

Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway حسب Kirti.S. Prabhu (17191231)

"…SNG treatment increased Bax/Bcl-2 ratio, which contributed to a leaky mitochondrial membrane leading to cytochrome c release accompanied by caspase activation. …"

Teachers’ Job Satisfaction in Instructional Delivery Modalities, and the Role of School Leaders: a Study among Selected Private Schools in Abu Dhabi. حسب YAHYA, AHMAD

"…For example, the interviews recommended that school leaders are invited to build an active channel of communication with their teachers, share the decision-making process with them, decrease the workload, raise the teachers’ autonomy, and establish a remuneration system.…"
احصل على النص الكامل

The Impact of Total Quality Management for achieving Sustainable Project Management حسب HUSSEIN, FUAD BASSAM FUAD

"…The findings of the research concluded that there lies a significant and positive impact of applying total quality management approaches to the sustainable outcomes of the projects in the UAE region. …"
احصل على النص الكامل

Ultrasound‑triggered herceptin liposomes for breast cancer therapy حسب Elamir, Amal

"…Exposing the liposomes to low-frequency ultrasound (LFUS) triggered drug release which increased with the increase in power density. Trastuzumab conjugation resulted in enhancing the sensitivity of the liposomes to LFUS. …"
احصل على النص الكامل

Assessment of High-resolution Local Emissions and Land-use in Air Quality Forecasting at an Urban, Coastal, Desert Environment حسب Christos Fountoukis (4722963)

"…The model’s forecast accuracy was assessed against measurement data from five ground air quality monitoring stations in the greater metropolitan area of Doha over a one-month period. …"

The Effects of Online Formative and Summative Assessment on Test Anxiety and Performance: A Study Among First-Year Undergraduate Students at A Higher Education Institution in Abu D... حسب ALSUWAIDI, MUNA

"…The presented study was conducted to provide greater insight into the potential positive, neutral and/or negative effects of online formative and summative assessment on test anxiety and performance. …"
احصل على النص الكامل

Composite hydrogels from carrageenan-cl-carboxymethyl chitosan–PVA incorporated ZiF-8 as dressing material for wound healing applications حسب Tooba Yasin (19131382)

"…The biocompatibility of the composite hydrogels has been evaluated using fibroblast cell lines (<i>3T3</i>) after different time intervals (24–72 h), and it was found that increasing ZiF-8 caused the mature and spread cell morphology with increasing cell viability and proliferation under controlled in vitro conditions. …"