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281
Unraveling the future productivity burden of cardiovascular disease in Qatar: Investigating the modifiable risk factors control in type 2 diabetes
Published 2025“…The financial value of PALYs was determined based on the gross domestic product (GDP) per full-time worker (i.e. US$80,573). The base-case model estimated the productivity burden of CVD, and interventional scenarios were simulated to assess potential gains resulting from improved control of modifiable risk factors, including reduced incidence of T2D, lower systolic blood pressure (SBP), decreased number of smokers, and reduced total cholesterol. …”
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282
Alterations in Beta Cell Identity in Type 1 and Type 2 Diabetes
Published 2019“…In diabetes, (1) endocrine identity recapitulates the less mature/less-differentiated fetal/neonatal cell type, possibly representing an adaptive mechanism; (2) residual β cells may be altered in their subtype proportions or other molecular features; (3) in humans, “altered identity” is a preferable term to dedifferentiation as their cellular fate (differentiated cells losing identity or progenitors becoming more differentiated) is unclear as yet.…”
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283
Road users with hearing loss and evaluation of tactile support systems
Published 2015“…The prevalence of age-related HL is increasing (Roth et al., 2001), and as a consequence the number of road users with HL will also increase. …”
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284
Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases
Published 2010“…Transcutaneous ultrasonography is even less invasive but often less accurate.9 Finally, positron emission tomography (PET) using fluorine-18–labeled deoxyglucose detects increased metabolic activity (uptake). …”
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285
The cost-benefit associated with the maturity of the Antimicrobial Stewardship Program versus prematurity in Heart Hospital of Hamad Medical Corporation in Qatar
Published 2023“…With M-ASP, cost of hospital tests use ‘decreased’ by QAR 1,149 per 100-patient beds per year, cost of ASP personnel ‘decreased’ by QAR 125 per 100-patient beds with the M-ASP, cost of drug use ‘increased’ by QAR 176,848 per 100-patient beds, cost of resistance and hospitalization ‘increased’ by QAR 216,279 per 100-patient beds per year. …”
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286
Foreign currency borrowing by small firms in emerging markets
Published 2013“…Bank relationships, however, do not increase the dollar debt likelihood. And finally, profitable firms are less likely to have dollar debt. …”
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287
Giving fragile bones a stronger foothold
Published 2016“…In the West, diagnosis, treatment and research of the condition, which causes bones to become fragile, have increased. But less attention is given to it in the Middle East and Africa, with only a few countries in both regions providing accessible guidelines for its prevention and treatment. …”
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288
Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes
Published 2023“…Three DNAJB3 knockout (KO) lines were generated (KO 30, 44 and 47), using CRISPR-Cas9. …”
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289
Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death
Published 2023“…This is followed by an increase in lipid peroxidation which peaks at later timepoints and varies between different cell lines. …”
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290
Bio-mimicry and Urban Design A case study of Sheikh Mohammed bin Zayed City
Published 2018“…I am also very grateful to my family for their continued support and their prayer to me to have a successful journey in BUID and in the rest of my life. Finally, many thanks to all professors and academic staff who were there to develop my learning skills and knowledge in order to increase my efficient working experience in both academic and working fields.…”
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291
Rising blood pressure in Bangladesh
Published 2015“…Hypertension and cardiovascular diseases have recently increased in South-East Asia as a result of rapid urbanization, increased life expectancy, and lifestyle changes. …”
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292
A review on the current status and post‑pandemic prospects of third‑generation biofuels
Published 2022“…It was found that several strategies during the life cycle of algal biofuel production can sig nifcantly increase its quality and yield while reducing cost, energy, and other related attributes. …”
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293
Size Increment During Surveillance in Papillary Thyroid Cancer: Evidence Synthesis and Dose–Response Meta‐Analysis
Published 2025“…</p><h3>Conclusion</h3><p dir="ltr">It was concluded that progression over the threshold increases linearly over time at approximately less than 1% per year. …”
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294
Cost-Effectiveness Analysis of Sacubitril/Valsartan for Reducing the Use of Implantable Cardioverter-Defibrillator (ICD) and the Risk of Death in ICD-Eligible Heart Failure Patient...
Published 2022“…Sacubitril/valsartan resulted in a relative increase of 0.04 quality-adjusted life year (QALY) and 0.67 years of life lived (YLL)/person, with an incremental cost increase of QAR13,952 (USD3,832). …”
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295
Anticancer activity of Neosetophomone B by targeting AKT/SKP2/MTH1 axis in leukemic cells
Published 2022“…<p>Neosetophomone B (NSP–B), a meroterpenoid fungal secondary metabolite, was investigated for its anticancer potential in leukemic cell lines (K562 and U937). NSP-B treatment of leukemic cells suppressed cell viability by triggering apoptotic cell death. …”
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296
Scalable Generation of Mesenchymal Stem Cells and Adipocytes from Human Pluripotent Stem Cells
Published 2020“…Disruption of cell adhesion induced the subsequent differentiation of the highly expanded RA-derived EB-forming cells into a pure population of multipotent MSCs (up to 1542-fold increase in comparison to RA-untreated counterparts). …”
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297
Investigating the Fluorescence Quenching of Doxorubicin in Folic Acid Solutions and Its Relation to Ligand-Targeted Nanocarriers
Published 2015“…The folate receptor is widely expressed on the surface of several cell lines and tumors; including ovarian, brain, kidney, breast, and lung cancers. …”
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298
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CORROSION OF FUSION-BONDED EPOXY COATED BARS IN CHLORIDE-CONTAMINATED PLAIN AND SiLICA FUME CEMENT CONCRETES EXPOSED TO VARYING TEMPERATURE
Published 2020“…The corrosion current density on mild steel and damaged FBEC bars was noted to increase with an increase in temperature. The performance of FBEC bars in the silica fume cement concrete was better than that in the plain cement concrete at both normal and elevated temperatures. …”
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300
Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018)
Published 2018“…Cytotoxicity of [HuArgI (Co)-PEG5000] was tested on two GBM cell lines, namely A172 and U251. Both cell lines showed increased sensitivity at longer incubation periods of [HuArgI (Co)-PEG5000] treatment with IC50 values in the pM range, a result attributable to the arginine auxotrophy expressed in those two cell lines. …”
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