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  1. 481

    Soluble ACE2 and angiotensin II levels are modulated in hypertensive COVID-19 patients treated with different antihypertension drugs by Mohamed A. Elrayess (21398687)

    Published 2022
    “…Their effect on circulating levels of ACE2 and angiotensin II, as well as the severity of COVID-19, is less well studied.</p><h3>Materials and methods</h3><p dir="ltr">The clinical data were collected from 200 patients in four different antihypertensive medication classes (ACEi, ARB, BB, and CCB). …”
  2. 482

    Comparative efficacy and safety of PD-1/PD-L1 inhibitors in triple negative breast cancer: a systematic review and network meta-analysis of randomized controlled trials by Ibrahim Elmakaty (14614270)

    Published 2023
    “…They were associated with an increase in immune-related adverse effects. When used early in the course of TNBC, PD-1/PD-L1 inhibitors exert their maximum benefit. …”
  3. 483
  4. 484

    The safety of outpatient total shoulder arthroplasty: a systematic review and meta-analysis by Abdulaziz F. Ahmed (14150082)

    Published 2022
    “…Furthermore, unadjusted comparisons demonstrated significantly less total and major surgical complications, less total, major, and minor medical complications in favour of outpatient TSA. …”
  5. 485

    The impact of green supply chain management practices on environmental performance during COVID-19 period: the case of discretionary companies in the G-20 countries by El Khoury, Rim

    Published 2022
    “…It highlights the impact of green initiatives to cope with major disruptions and decrease pollution and environmental disaster.…”
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  6. 486

    Linear Domesticity: The Hong Kong Single Occupancy Strip by Carlow, Jason

    Published 2015
    “…The Hong Kong Single Occupancy Strip (HK:SOS) project is a response to a growing housing crisis in Hong Kong, in which the domestic environments of the future are becoming more unaffordable and less habitable. In reaction to the increasing cost and shrinking size of Hong Kong housing units, the HK:SOS project explores the challenges and limitations of living in minimally sized spaces by producing a linear apartment for a single individual. …”
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  7. 487

    Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021 by Austin, Carter

    Published 2024
    “…Four of the seven GBD super-regions had a lifetime probability of less than 1% in 2021. In 2021, sub-Saharan Africa had the highest PUV of 999·9 (857·4–1154·2) per 100 000 population, but this was a 64·5% (58·8–69·4) reduction in PUV from 2003 to 2021. …”
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  8. 488

    A control algorithm to increase the efficient operation of wind energy conversion systems under extreme wind conditions by Nyam Jargalsaikhan (17380429)

    Published 2022
    “…<p dir="ltr">This paper aims to increase the power production of gearless permanent magnet synchronous generator (PMSG) based wind energy conversion systems (WECS) in strong (greater than 25 m/s) wind speed regions. In general, most wind turbines cut off when wind speed is over the cut-out rate; as a result, the power generation of the wind farm decreases. …”
  9. 489

    A screening instrument for sleep apnea predicts airway maneuvers in patients undergoing advanced endoscopic procedures by Azar, Riad

    Published 2010
    “…SRCs were defined as any duration of pulse oximetry less than 90%, systolic blood pressure less than 90 mm Hg, apnea, or early procedure termination. …”
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  10. 490

    Characterizing the transitioning epidemiology of herpes simplex virus type 1 in the USA: model-based predictions by Houssein H. Ayoub (9262512)

    Published 2019
    “…</p><p><br></p><h3>Conclusion</h3><p dir="ltr">HSV-1 epidemiology is undergoing a remarkable transition in the US, with less exposure in childhood and more in adulthood, and less oral but more genital acquisition. …”
  11. 491

    Gender gap in mental health research productivity: Results from Qatar by Dalia Albahari (17115664)

    Published 2020
    “…<h3>Objectives</h3><p dir="ltr">Qatar’s contribution to biomedical research has increased significantly in the past couple of decades, but the exact participation of women researchers remains obscure. …”
  12. 492

    Lead exposure of Bangladeshi women at childbearing age: Does mother's education reduce fetal risk factors? by Sharmind Neelotpol (19732277)

    Published 2016
    “…A questionnaire survey was conducted among the participants comprising both less-educated (<i>n</i> = 62) and more-educated (<i>n</i> = 52) women. …”
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  15. 495

    Research on the potential of photovoltaic technologies in reducing energy consumption in an urban mixed use residential community. A Case study for net zero energy community in Dub... by SUGATHAN, SANAL

    Published 2018
    “…Therefore, the key challenge is to reduce the consumption of fossil fuels which decreases the production of greenhouse gases such as CO2 and CH4 by using renewable energy technologies to provide clean carbon free energy that can combat future energy security challenges. …”
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  16. 496

    A novel inhibitor of STAT3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells by Abou-Ghazal, Mohamed K.

    Published 2008
    “…Results WP1066 achieved an IC50 of 1.6 μM, 2.3 μM, and 1.5 μM against melanoma cell line A375, B16 and B16EGFRvIII, respectively. WP1066 suppressed the phosphorylation of JAK2 and STAT3 (Tyr705) in these cells. …”
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  17. 497

    A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T ce... by Abou-Ghazal, Mohamed

    Published 2008
    “…Experimental Design: The antitumor activities and related mechanisms of WP1066 were investigated both in vitro on melanoma cell lines and in vivo on mice with subcutaneously syngeneic melanoma or with intracerebral melanoma tumors. …”
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  18. 498

    Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation by Shilpa Kuttikrishnan (3520079)

    Published 2025
    “…Prist significantly increases reactive oxygen species (ROS) levels and depletes glutathione (GSH), leading to mitochondrial dysfunction and cytochrome c release. …”
  19. 499

    Protein arginine methyltransferase 5 (PRMT5) activates WNT/β‐catenin signalling in breast cancer cells via epigenetic silencing of DKK1 and DKK3 by Harshita Shailesh (14779408)

    Published 2023
    “…<p></p><div> <p>Protein arginine methyltransferase 5 (PRMT5) activity is dysregulated in many aggressive cancers and its enhanced levels are associated with increased tumour growth and survival. However, the role of PRMT5 in breast cancer remains underexplored. …”
  20. 500

    Inositol 1,4,5-Trisphosphate Receptors in Hypertension by Ali H. Eid (5461829)

    Published 2018
    “…This involves a phenotypic switch of VSMCs as well as an alteration of cytoplasmic Ca<sup>2+</sup> signaling machinery, a phenomena tightly related to the aging process. Several lines of evidence implicate changes in expression/function levels of IP<sub>3</sub>R isoforms in the development of hypertension, VSMC phenotypic switch, and vascular aging. …”