Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro حسب Najem, Sonia A.

"…Objective: In this study, we evaluated the effect of Suberoylanilide Hydroxamic Acid (SAHA), a panhistone deacetylase inhibitor, and Decitabine (DAC), a DNA methyltransferase inhibitor, either alone or in combination, on Caco-2 human colon cancer cell line in vitro. Results: Our results showed that SAHA and DAC, separately, significantly decreased cell proliferation, induced apoptosis and cell cycle arrest of Caco-2 cell line. …"
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Rebound effects undermine carbon footprint reduction potential of autonomous electric vehicles حسب Nuri C. Onat (14779093)

"…<p dir="ltr">Autonomous vehicles offer greater passenger convenience and improved fuel efficiency. …"

Indirect tool-wear maps for tool condition monitoring in dry metal drilling operations حسب Ammouri, A.H.

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Reputation-Based Cooperative Detection Model of Selfish Nodes in Cluster-Based QoS-OLSR Protocol حسب Moati, Nadia

"…The QOLSR is a multimedia protocol that was designed on top of the optimized link state routing (OLSR) protocol for mobile ad hoc network. …"
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Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia حسب Shilpa Kuttikrishnan (3520079)

"…Curcumin induces apoptosis in B-Pre-ALL cell lines via activation of caspase-8 and truncation of BID. …"

Water-pipe smoking promotes epithelial–mesenchymal transition and invasion of human breast cancer cells via ERK1/ERK2 pathways حسب Khaled W. Sadek (14153196)

"…Two breast cancer cell lines, MCF7 and BT20, were used in this investigation. …"

Developing a Hybrid Model for Network Planning in Abu Dhabi Distribution Company Subsidiary of Adwea حسب Al Haddabi, Aseya Mohammed

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Effect of nickel loading on hydrogen production and chemical oxygen demand (COD) destruction from glucose oxidation and gasification in supercritical water حسب Youssef, Emhemmed A.

"…Results also showed that the presence of Ni increased the total gas yield increased in the 7.5–18 wt Ni/Al2O3 catalyst. …"
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Effect of fasting on laryngopharyngeal reflux disease in male subjects حسب Hamdan, Abdul-Latif

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DLC2/StarD13 plays a role of a tumor suppressor in astrocytoma حسب El-Sitt, Sally

"…Finally, we detected an increase in p-ERK in StarD13 knockdown cells, uncovering a potential link between Rho GTPases and ERK activation.…"
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Flavin Adenine Dinucleotide (FAD) and Pyridoxal 5′-Phosphate (PLP) Bind to Sox9 and Alter the Expression of Key Pancreatic Progenitor Transcription Factors حسب Zeyaul Islam (5867387)

"…Previously, there was no known link between FAD, PLP, or other co-factors and Sox9 for function. …"

PSA-activated proaerolysin as a prostate specific cancer therapy حسب Abi-Habib, Ralph

"…The goal of this study was to examine the suitability of PRX302 for use as a therapeutic agent in prostate cancer and benign prostatic hyperplasia as assessed by comparing proteolytic activation of PRX302 and native proaerolysin and their cytotoxicity towards PSA-producing and non-producing cell lines. Modification of native proaerolysin to PRX302 markedly altered the activity of each of the proteases (chymotrypsin, trypsin, furin, and thrombin) tested toward this protein. …"
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Deep Learning-Based Fault Diagnosis of Photovoltaic Systems: A Comprehensive Review and Enhancement Prospects حسب Majdi Mansouri (16869885)

"…These faults may affect the different system components such as PV modules, connection lines, converters/inverters, which can lead to a decrease in the efficiency, performance, and further system collapse. …"

Snake venom in conjugation with silica nanoparticles: an emerging cancer therapy حسب Duaa Azam (22502048)

"…<i>In vitro</i> investigations on cancer cell lines revealed a considerable increase in cytotoxicity and induction of apoptosis as compared to free snake venom, with greater selectivity for malignant cells. …"

Sustainable Financing for Sustainable Development: Agent-Based Modeling of Alternative Financing Models for Clean Energy Investments حسب Ibrahim Ari (12058516)

"…This substantial amount of borrowing makes a negative contribution to the high global debt concentration, putting countries’ economic and social development at risk. In line with this, excessive debt-based financing causes an increase in wealth inequality, and when wealth inequality reaches a dramatic level, wars and many other social problems are triggered to correct the course of wealth inequality. …"

Integrated Demand Side Management in Network Planning for Utility Companies حسب Khalfan, Fatma Mohamed

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Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF) 1 حسب Nasser, Selim

"…In this study, we attempt to target both the urokinase plasminogen activator and the mitogen-activated protein kinase pathway in acute myeloid leukemia (AML) cell lines and primary AML blasts using PrAgU2/LF, a urokinase-activated anthrax lethal toxin. …"
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Loss of the TRPM4 channel in humans causes immune dysregulation with defective monocyte migration حسب Fang Yu (156838)

"…<h3>Background</h3><p dir="ltr"><u>TRPM4</u> is a broadly expressed, calcium-activated, <u>monovalent</u> cation channel that regulates <u>immune cell</u> function in mice and cell lines. Clinically, however, partial loss- or gain-of-function mutations in <i><u>TRPM4</u></i> lead to <u>arrhythmia </u>and<u> heart disease</u>, with no documentation of<u> immunologic disorders.…"

Evaluation of pretreatment and membrane configuration for pressure-retarded osmosis application to produced water from the petroleum industry حسب Dareen Dardor (17052381)

"…PRO is typically considered with seawater/river water pairings however greater energy can be recovered from hypersaline solutions including produced water (PW) from the petroleum industry. …"

Graphite and metal nitrate-infused HDPE composites for enhanced thermal performance in energy-efficient building envelopes حسب Mohammad Amir Khan (23770803)

"…Analysis such as Fourier Transform Infrared Spectroscopy (FTIR), X-ray Diffraction (XRD), Differential Scanning Calorimetry (DSC), Thermogravimetric Analysis (TGA), Scanning Electron Microscopy (SEM), and dielectric spectroscopy analyses further revealed extensive interaction between filler matrices, a decrease in phonon scattering, and a positive increase in crystallinity which led to the improved thermal performance.The TGA results showed that the composite exhibited greater thermal stability, and the residue mass after the decomposition process was 9%, indicating increased carbonization and structural integrity. …"