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Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway
منشور في 2022"…<p dir="ltr">Non-alcoholic fatty liver disease (NAFLD) is the leading chronic liver disease worldwide. …"
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Why wear a seat belt? I’m going to die anyway: Young Arab men’s rationales for deadly driving behaviors
منشور في 2015"…A second generation of campaigns has recently been developed that are also fear appeal based, but feature more sophisticated messaging and visuals than the first group did. While laudable in their goals, both set of campaigns are not based on either a theoretical framework or research on the target audience. …"
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Phosphorus supplementation increases thermic response to glucose solution in healthy lean subjects
منشور في 2013"…Baseline fasting resting metabolic rate (RMR) and VO2 did not differ between the 2 studies (1.2±0.2kcal/min and 250±37mL/min, respectively; p=0.92). …"
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Risk of Malignancy in Indeterminate Liver Nodules Among Patients with Cirrhosis: A Retrospective Cohort Study
منشور في 2024"…</p><h3>Conclusion</h3><p dir="ltr">Our findings show a higher incidence of HCC in patients with indeterminate liver nodules, increasing over time and reaching 30% at seven years. …"
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Surgical Strategies for Synchronous Colorectal Liver Metastases in 156 Consecutive Patients
منشور في 2015"…Background An increasing number of patients with synchronous colorectal liver metastases (CLM) are candidates for resection. …"
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Tragopogon porrifolius improves serum lipid profile and increases short-term satiety in rats
منشور في 2013"…Food intake, abdominal fat percentage, blood lipid profile, liver weight and liver enzymes were assessed following 4 weeks of extract intake via drinking water (50, 100, or 250 mg/kg body weight) in standard high-carbohydrate and high-fat dietary conditions. …"
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Chemotherapy prior to Hepatic Resection for Colorectal Liver Metastases: Helpful until Harmful?
منشور في 2009"…Steatohepatitis is associated with irinotecan therapy and an increased risk for liver failure and death after hepatic resection. …"
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Systemic Chemotherapy and Two-Stage Hepatectomy for Extensive Bilateral Colorectal Liver Metastases
منشور في 2007"…Background Two-stage hepatectomy has been proposed for patients with bilateral colorectal liver metastases (CLM). The aim of this study was to compare the outcome of patients with CLM treated with preoperative chemotherapy followed by one- or two-stage hepatectomy. …"
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Novel biomarkers for potential risk stratification of drug induced liver injury (DILI)
منشور في 2019"…<h3>Background:</h3><p dir="ltr">Drug induced liver injury (DILI) is an increasing cause of acute liver injury especially with increasing need for pharmacotherapy of widening comorbidities amongst our ever-aging population. …"
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Noncoding RNAs in Nonalcoholic Fatty Liver Disease: Potential Diagnosis and Prognosis Biomarkers
منشور في 2020"…<p>Nonalcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease worldwide in part due to the concomitant obesity pandemic and insulin resistance (IR). …"
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The Association of Hypertension with Increased Mortality Rate During the COVID-19 Pandemic: An Update with Meta-analysis
منشور في 2023"…Out of the 611,522 patients, 3119 died which resulted in an overall mortality prevalence of 0.5%. …"
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Chemotherapy Regimen Predicts Steatohepatitis and an Increase in 90-Day Mortality After Surgery for Hepatic Colorectal Metastases
منشور في 2006"…Patients with steatohepatitis had an increased 90-day mortality compared with patients who did not have steatohepatitis (14.7% v 1.6%, respectively; P = .001; OR = 10.5; 95% CI, 2.0 to 36.4). …"
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Increased leptin expression in mice with bacterial peritonitis is partially regulated by tumor necrosis factor alpha
منشور في 1998"…Plasma leptin and ob gene mRNA levels were increased in mice following bacterial peritonitis, and blocking an endogenous tumor necrosis factor alpha (TNF-α) response blunted the increase. …"
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Deep learning-based modeling of land use/land cover changes impact on land surface temperature in Greater Amman Municipality, Jordan (1980–2030)
منشور في 2024"…This study aimed to model past, present, and future LULCC on Land Surface Temperatures in the Greater Amman Municipality (GAM) in Jordan between 1980 and 2030. …"
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Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases
منشور في 2010"…For example, a few years ago an extrahepatic metastasis effectively eliminated surgical resection, but a combination of chemotherapeutic options and surgical techniques has expanded the indications for resection and increased the population of patients who may benefit.1,2 Neoadjuvant chemotherapy has increased the resectability rate by 11% to 37%.1 Unfortunately, greater than 80% of patients undergoing hepatic resection will have recurrences, mostly within the first 2 years.2 Nonetheless, the only hope for cure is resection, and prior surgical dogma based on the number of lesions, size of the tumor-free resection margin, and presence of resectable extrahepatic disease must be questioned.3- 5 The current standard approach to surgical planning is contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI) for specific tumor characteristics or contraindications to CT.6 Several series showed that focal extrahepatic disease, an isolated pulmonary lesion, can be safely resected, with 5-year survival rates of 29% to 58%.7,8 In 1 series,7 17 of 30 patients required 3 or more resections. …"
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