Characterization of the Potency and Mechanism of Action of a Novel Dual-Selective Intermolecularly Complemented Version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Breas... حسب Basala, Sobhiya

"…Since IMC/FP59 had cytotoxic effect on MDA-MB-231 cells, the type of cell death was investigated by staining for Annexin V/PI, and there was no evidence of apoptosis. Later we detected uPAR levels in breast cancer cell lines. …"
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Manipulating away the dizziness حسب Nature Research (16552612)

Salivary α-amylase activity is associated with cardiometabolic and inflammatory biomarkers in overweight/obese, non-diabetic Qatari women حسب Neyla S. Al Akl (15189997)

"…<h3>Introduction</h3><p dir="ltr">Obesity, prevalent in approximately 80% of Qatar’s adult population, increases the risk of complications like type 2 diabetes and cardiovascular diseases. …"

Epigenetic DNA Methylation Signatures Associated With the Severity of Paget’s Disease of Bone حسب Ilhame Diboun (3522413)

"…<h3>Background: </h3><p dir="ltr">Paget’s disease of bone (PDB) is characterized by focal areas of dysregulated bone turnover resulting in increased bone loss and abnormal bone formation with variable severity. …"

Novel proteins implicated in lipid metabolism disorders حسب Nature Research (16552612)

The Effect of Atorvastatin (and Subsequent Metformin) on Adipose Tissue Acylation-Stimulatory-Protein Concentration and Inflammatory Biomarkers in Overweight/Obese Women With Polyc... حسب Thozhukat Sathyapalan (704787)

"…In pro-inflammatory states such as PCOS, spontaneous activation of the alternative pathway of complement results in increased generation of acylation stimulating protein (ASP) from adipocytes irrespective of body mass index.…"

Genomic Landscape And Structural Impact Of Biotinidase (BTD) Variants In A Middle Eastern Population حسب BalaSubramani Gattu Linga (19325617)

HIV incidence among people who inject drugs in the Middle East and North Africa: mathematical modelling analysis حسب Ghina R Mumtaz (18629722)

"…In addition, 20 to 2208 and 5 to 837 new annual infections were estimated across the different countries among sexual partners of PWID and ex‐PWID respectively. …"

Adipocyte Enhancer-Binding Protein 1 (AEBP1) (a Novel Macrophage Proinflammatory Mediator) Overexpression Promotes and Ablation Attenuates Atherosclerosis in ApoE⁻′⁻ and LDLR⁻′⁻ Mi... حسب Bogachev, Oleg

"…Macrophages from ApoE⁻′⁻/TG-BM chimeric mice express reduced levels of PPARγ₁, LXRα, ATP-binding cassette A₁ (ABCA₁) and ATP-binding cassette G₁ (ABCG₁) and increased levels of the inflammatory mediators interleukin (IL)-6 and tumor necrosis factor (TNF)-α compared with macrophages of control chimeric mice (ApoE⁻′⁻/NT-BM) that received AEBP₁ nontransgenic (AEBP₁ᴺᵀ) BM cells. …"
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Helios Should Not Be Cited as a Marker of Human Thymus-Derived Tregs. Commentary: Helios+ and Helios− Cells Coexist within the Natural FOXP3+ T Regulatory Cell Subset in Humans حسب Eyad Elkord (5396390)

"…Shevach’s group reported that Helios expression discriminates tTregs from pTregs (5). This work generated a lot of excitement due to the real need for markers to discriminate the good tTregs from the bad pTregs. …"

The interplay between social media use and problematic internet usage: Four behavioral patterns حسب Khansa Chemnad (17346994)

"…Those who were in Cluster 3 (Conversational SM Cluster; Cluster size = 19, 5.69% of total dataset) all used WhatsApp, and spent between 76.68 and 225.22 min on WhatsApp daily. …"

Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 حسب Olfa Khalifa (10914452)

Measuring the availability of human resources for health and its relationship to universal health coverage for 204 countries and territories from 1990 to 2019: a systematic analysi... حسب Annie Haakenstad (673009)

"…</p><h3>Findings</h3><p dir="ltr">We estimated that, in 2019, the world had 104·0 million (95% uncertainty interval 83·5–128·0) health workers, including 12·8 million (9·7–16·6) physicians, 29·8 million (23·3–37·7) nurses and midwives, 4·6 million (3·6–6·0) dentistry personnel, and 5·2 million (4·0–6·7) pharmaceutical personnel. …"

Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018 حسب Damaris Kinyoki (3458885)

Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration حسب Megan F. Duffy (5713772)

"…</p><h3>Conclusions</h3><p dir="ltr">Our results demonstrate that increases in microglia displaying a reactive morphology and MHC-II expression occur in the substantia nigra in close association with peak numbers of pSyn inclusions, months prior to nigral dopamine neuron degeneration, and suggest that reactive microglia may contribute to vulnerability of SNc neurons to degeneration. …"