A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…Gaussian accelerated molecular dynamics (GaMD) simulations of the predicted alpha-helical synthetic Mpro cleavage sequences revealed a dynamic nature of the cleavage sequences, which is critical for their efficient cleavage, and a relatively short end-to-end distances, which is required for high BRET. Live cell assays revealed a cleavage sequence length-dependent resonance energy transfer, except for the 12× -syn cleavage site, and an increased rate of cleavage and a decreased pharmacological inhibitor efficacy for the Mpro biosensor containing 2× cleavage sequences. …”
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Papillary Thyroid Carcinoma with Fibromatosis/Fasciitis-Like/Desmoid-Type Stroma: Case Report of a Rare Subtype with Cytological and Molecular Study by Hosamadean Benghashir (22224895)

“…<h3>Background</h3><p dir="ltr">Papillary thyroid carcinoma (PTC) with fibromatosis/fasciitis-like/desmoid-type stroma is a rare subtype of PTC,characterized by two distinct components: a classic papillary carcinoma component and a spindle cell proliferationresembling fibromatosis or nodular fasciitis. …”

Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection? by Abu Saleh Md Moin (6189512)

“…</p><h3>Conclusion</h3><p dir="ltr">Hypoglycemia potentiated both plasma sNRP1 level elevation and its ligands VEGF and SEMA3A, likely through an ADAM9-mediated mechanism that was not associated with RAS overactivity or ACEi therapy; however, whether this is protective or promotes increased risk for SARS-CoV-2 infection in T2D is unclear.…”

Lipophilic Metabolites and Anatomical Acclimatization of Cleome amblyocarpa in the Drought and Extra-Water Areas of the Arid Desert of UAE by Soliman, Sameh S.M.

“…The plant showed the presence of shaggy-like trichomes. The plant also developed special mechanisms to ensure its survival via release of lipophilic metabolites. …”
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The impact of size on particle drainage dynamics and antibody response by Simon Zinkhan (14214245)

“…The size and the repetitive geometric shape of virus-like particles (VLPs) influence their immunogenicity by facilitating drainage to secondary lymphoid organs and enhancing interaction with and activation of B cells and innate humoral immune components. …”

The Extent to Which Schools with Mechanistic Structures and their Job Characteristics are Likely to Generate Teachers’ Organisational Commitment: Study Conducted in a Private Schoo... by Mansour, Hadi

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Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide. by Sara, Sokary

“…The global burden of overweight and obesity has increased by threefold since the 1970s, which led to increased incidences of cardiovascular disease and type 2 diabetes. …”
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“It's disappointing and it's pretty frustrating, because it feels like it's something that will never go away.” A qualitative study exploring individuals’ beliefs and experiences o... by Jeffrey Turner (341283)

“…</p><h3>Purpose</h3><p dir="ltr">To qualitatively explore the lived experiences of individuals with AT.</p><h3>Design</h3><p dir="ltr">A qualitative, interpretive description design was performed using semi-structured telephone interviews.…”

An overview of diabetes mellitus in pregnant women with obesity by Mohammed, Bashir

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Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019 by Jonathan M. Kocarnik (7512677)

“…The proportion of years lived with disability that contributed to DALYs increased with SDI, ranging from 1.4% (1.1%-1.8%) in the low SDI quintile to 5.7% (4.2%-7.1%) in the high SDI quintile. …”

Three-way decision-based conditional probabilities by opinion scores and Bayesian rules in circular-Pythagorean fuzzy sets for developing sustainable smart living framework by A. Alsattar, Hassan

“…Sustainable smart living (SSL) is a crucial component in the emergence of smart cities. …”
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Effect of Girder Damage on the Structural Behavior of Slab-on-Girder Bridges by Elozn, Ahmed E.

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Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019 by Razieh, Hassannejad

“…FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …”
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Living Materials: Preserving Student Innovation in Art and Science through Digital Twins and AI in Partnership with Qatar National Library : What Happens To Your Work After You Gra... by Arif Shaon (13761784)

“…The presentation also situates student work within a broader global research ecosystem, emphasizing citability, verification, and long-term impact in an era increasingly shaped by AI-generated content.</p><p dir="ltr">This resource is intended for students, educators, librarians, and institutions interested in sustainable models for preserving student innovation, practice-led research, and interdisciplinary creative outputs.…”

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 co... by Alize J, Ferrari

“…However, despite this overall increase, HALE decreased by 2·2% (1·6–2·9) between 2019 and 2021. …”
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Aryl Hydrocarbon Receptor Promotes Cell Growth, Stemness Like Characteristics, and Metastasis in Human Ovarian Cancer via Activation of PI3K/Akt, β-Catenin, and Epithelial to Mesen... by Lubna Therachiyil (4246156)

Performance evaluation of various growing media in vertical green wall for greywater treatment in hyper-arid climate by Jasir Jawad (17191468)

“…<p dir="ltr">Water scarcity in hyper-arid regions like the Middle East demands sustainable solutions to reduce reliance on energy-intensive desalinated water. …”

Exendin-4 promotes GSIS without increasing β-cell number through upregulation of glucose-sensing apparatus and mitochondrial oxidative phosphorylation machinery genes in hPSC-deriv... by Abdoulaye Diane (14152749)

“…This consists of 6 stages: S1, definitive endoderm; S2, gut tube endoderm; S3, pancreatic progenitors 1; S4, pancreatic progenitors 2; S5, endocrine precursors; and S6, β-like cells. To determine the differentiation efficiency, relevant stage-specific marker expression was assessed at each stage using flow cytometry. …”

Active Botanical Biofiltration in Built Environment to Maintain Indoor Air Quality by Mehzabeen Mannan (16442001)

The promise of tirzepatide: A narrative review of metabolic benefits by Sara Sokary (17337724)