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Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling
منشور في 2019"…Altogether our findings demonstrate that SNG induces mitochondrial and caspase-dependent apoptosis, generates oxidative stress, and suppresses MM cell lines proliferation. In addition, co-treatment of MM cell lines with sub-toxic doses of SNG and BTZ potentiated the cytotoxic activity. …"
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Assessing additional fuel consumption from cabin thermal comfort and auxiliary needs on the worldwide harmonized light vehicles test cycle
منشور في 2018"…Cabin heating and cooling can especially lead to considerable increase in vehicle energy consumption. This paper presents a simulation-based assessment framework to account for the additional fuel consumption related to the cabin thermal energy and auxiliary needs under the worldwide-harmonized light vehicles test procedure (WLTP). …"
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64
Investigations on Entrepreneurship Needs, Challenges, and Models for Countries in Transition to Sustainable Development from Resource-Based Economy—Qatar as a Case
منشور في 2023"…<p dir="ltr">This paper presents a comprehensive and comparative investigation into the needs, challenges, and potential roles for entrepreneurship in transforming resource-rich countries into sustainable economies. …"
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Evaluation of Microplastics in Beach Sediments along the Coast of Dubai, U.A.E
منشور في 2019احصل على النص الكامل
doctoralThesis -
66
Hexokinase-linked glycolytic overload and unscheduled glycolysis in hyperglycemia-induced pathogenesis of insulin resistance, beta-cell glucotoxicity, and diabetic vascular complic...
منشور في 2024"…Downstream effector pathways of HK-linked unscheduled glycolysis are mitochondrial dysfunction and increased reactive oxygen species (ROS) formation; activation of hexosamine, protein kinase c, and dicarbonyl stress pathways; and increased Mlx/Mondo A signaling. …"
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Perceptions and Views Regarding the Role of the Special Educational Needs and Disabilities Coordinators (SENDCos) and Challenges Affecting the Role in the United Arab of Emirates (...
منشور في 2017"…The expectations of the special and inclusive education have been rapidly increased over the last decade. Therefore, it is significant to introduce a person, such as the Special Educational Needs and Disabilities coordinator (SENDCo), who is able to lead the inclusion movement and bear the brunt of these changes in every school. …"
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68
Greensporone A, a Fungal Secondary Metabolite Suppressed Constitutively Activated AKT via ROS Generation and Induced Apoptosis in Leukemic Cell Lines
منشور في 2019"…We studied the anticancer activity of greensporone A in a panel of leukemic cell lines. Greensporone A-mediated inhibition of proliferation is found to be associated with the induction of apoptotic cell death. …"
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Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic...
منشور في 2021"…Spliceosomal gene expression correlated positively with Glo1 in human tumor cell lines and tumors. In clinical chemotherapy of breast cancer, increased expression of Glo1 was associated with decreased patient survival, with hazard ratio (HR) = 1.82 (logrank p < 0.001, n = 683) where upper quartile survival of patients was decreased by 64% with high Glo1 expression.…"
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Photoactivatable RuII Complex Bearing 2,9‐Diphenyl‐1,10‐phenanthroline: Unusual Photochemistry and Significant Potency on Cisplatin‐Resistant Cell Lines
منشور في 2018"…In conclusion, the Ru‐centered complex 1 could represent a potential photoactivatable chemotherapeutic drug that increases selectivity to tumors and offers alternative treatment in the light of increasing cisplatin resistance.…"
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72
The effectiveness of existing policies and procedures in the admission of students with SEND in the UAE higher education
منشور في 2018"…Inclusion of students with special needs and disabilities (SEND) in the schools would prepare to gain their rights through smoother process to access the higher education. …"
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73
A study of the development, implementation and perception of the ‘Towards Inclusive Schools Development Programme’ at three government primary schools in Lebanon
منشور في 2022"…The following areas of concern need to be addressed to ensure sustainable development of the programme in the future. …"
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74
An investigation into links between UAE STI Policy and the Federal Universities STEM Majors’ Enrolments, Graduates and Research Development: an evidence-based exploration of the im...
منشور في 2020"…Zayed University-Dubai had greater STEM majors’ enrolments compared to Zayed University-Abu Dhabi. …"
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75
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Managing Online Learning to Support Inclusion During COVID-19 in A Private School in Dubai
منشور في 2021"…Data was collected from teachers, Special educational needs, and disabilities students (SEND) and the inclusion coordinator. …"
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77
Wastewater reuse for livestock feed irrigation as a sustainable practice: A socio-environmental-economic review
منشور في 2021"…Interesting research directions include the need to investigate farmers’ concern about consumers’ attitude, which apparently obstructs them from adopting new technologies despite their improved harvests. …"
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Violent Extremism Prevention in the Era of Globalization
منشور في 2020"…The significance of the study stems from the fact that global strategizing efforts are needed to pay greater emphasis on the media and finance, specifically in weak and vulnerable states. …"
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masterThesis -
79
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…In this study we recorded maximum increase in total PP2A at 3 µM sodium selenate in a neuron cell line. …"