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A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T ce...
Published 2008“…Results: WP1066 achieved an IC50 of 1.6, 2.3, and 1.5 μmol/L against melanoma cell line A375, B16, and B16EGFRvIII, respectively. …”
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203
Novel proteins implicated in lipid metabolism disorders
Published 2016“…</p><p>ANGPTL3 is a protein secreted by the liver, belonging to the angiopoietin-like family of eight proteins. …”
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204
Transport, magnetic and structural properties of(Tl0.5Pb0.5)Sr2-xCexCa2Cu3Oy compounds
Published 2000“…Resistivity, DC magnetization and X-ray diffraction measurements were performed on 6 sample with nominal composition (Tl0.5Pb 0.5)Sr2-xCexCa2Cu3 Oy, with x=0.0, 0.1, 0.2, 0.3, 0.4 and 0.5. As cerium content was increased, the transition temperature increased up to about 6 K when x=0.1. …”
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ZnO-Doped gC<sub>3</sub>N<sub>4</sub>Nanocapsules for Enhancing the Performance of Electroless NiP Coating─Mechanical, Corrosion Protection, and Antibacterial Properties<sub>3</sub...
Published 2023“…The highest corrosion resistance is achieved on the heat-treated NiP-C<sub>3</sub>N<sub>4</sub>/1.0 wt % ZnO coatings. Although the presence of ZnO in the C<sub>3</sub>N<sub>4</sub> nanocapsules increased its surface area and porosity, the C<sub>3</sub>N<sub>4</sub>/ZnO nanocapsules prevented localized corrosion by filling the microdefects and pores of the NiP matrix. …”
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Development of flexible PVDF/ BaTiO<sub>3</sub>-MoS<sub>2</sub> polymer nanocomposites for energy harvesting and gas sensing applications
Published 2024“…The electroactive, β-phase of the PVDF is shown to increase with the addition of BaTiO<sub>3</sub>–MoS<sub>2</sub> fillers as a result of the filler’s good interfacial interaction with the polymer matrix. …”
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207
Recognizing Plastic Threats in Baggage X-Rays Using Deep Networks
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doctoralThesis -
208
Omega-3 fatty acid-rich fish oil supplementation prevents rosiglitazone-induced osteopenia in aging C57BL/6 mice and in vitro studies
Published 2022“…<p>Rosiglitazone is an effective insulin-sensitizer, however associated with bone loss mainly due to increased bone resorption and bone marrow adiposity. …”
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A novel design for battery cooling based on highly thermally conductive phase change composites encapsulated by 3D printed polyethylene/boron nitride layer
Published 2025“…Phase change materials (PCM) are increasingly studied for battery thermal management due to their passive thermal storage capacity and temperature homogeneity. …”
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Epidemiological and genetic characterization of pH1N1 and H3N2 influenza viruses circulated in MENA region during 2009–2017
Published 2019“…Furthermore, nucleotide variations were lower at the antigenic sites of pH1N1 viruses compared to H3N2 viruses, which experienced higher variability at the antigenic sites, reflecting the increased immunological pressure because of longer circulation and continuous vaccine changes. …”
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Inositol 1,4,5-Trisphosphate Receptors in Hypertension
Published 2018“…Several lines of evidence implicate changes in expression/function levels of IP<sub>3</sub>R isoforms in the development of hypertension, VSMC phenotypic switch, and vascular aging. …”
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Helios Should Not Be Cited as a Marker of Human Thymus-Derived Tregs. Commentary: Helios+ and Helios− Cells Coexist within the Natural FOXP3+ T Regulatory Cell Subset in Humans
Published 2016“…</p><p dir="ltr">Taken together, Helios expression confers stable phenotype of Tregs, and FoxP3<sup>+</sup>Helios<sup>+</sup> Tregs have enhanced immunosuppressive characteristics, compared with FoxP3<sup>+</sup>Helios<sup>−</sup> Tregs (8, 15). …”
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Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways
Published 2015“…Flow cytometric analysis indicated that both fractions induced sub-G1 phase accumulation and increased apoptotic cell death. Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. …”
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The Immunophenotyping Changes of Peripheral CD4+ T Lymphocytes and Inflammatory Markers of Class III Obesity Subjects After Laparoscopic Gastric Sleeve Surgery – A Follow-Up Study...
Published 2021“…The study aimed to follow up on the changes in the peripheral CD4+ T lymphocytes and the pro-inflammatory cytokines; IL-6, TNF-alpha, MCP-1, and IL-10 at baseline and 12 weeks post-surgical intervention by the laparoscopic gastric sleeve (LGS) in morbidly obese patients (class III obesity subjects). </p><h3>Materials and Methods </h3><p dir="ltr">A prospective longitudinal research included 24 class III obesity subjects with a BMI > 40 kg/m<sup>2</sup>. …”
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An experimental and first principles DFT investigation on the effect of Cu addition to Ni/Al<sub>2</sub>O<sub>3</sub> catalyst for the dry reforming of methane
Published 2020“…DFT calculations reveal increased energy barrier for carbon adsorption, whilst promoting facile removal of deposited carbon. …”
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Deciphering the In vitro Role of microRNAs miR-21-3p and miR-222-5p In the Regulation of Clostridioides difficile Flagellin-Induced Inflammation
Published 2024“…Western blot and pathway analyses demonstrated that miR-222-5p and miR-21-3p overexpression increased phosphorylation of p65, a key component of the NF-κB complex, while their knockdown reduced p65 phosphorylation. …”
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masterThesis -
217
Protein arginine methyltransferase 5 (PRMT5) activates WNT/β‐catenin signalling in breast cancer cells via epigenetic silencing of DKK1 and DKK3
Published 2023“…Through chromatin immunoprecipitation (ChIP) studies, we found that PRMT5 binds to the promoter region of WNT antagonists, <i>DKK1</i> and <i>DKK3</i>, and induces symmetric methylation of H3R8 and H4R3 histones. …”
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Double versus triple arthrodesis for adult-acquired flatfoot deformity due to stage III posterior tibial tendon insufficiency: a prospective comparative study of two cohorts
Published 2022“…The mean time to union in the double and triple arthrodesis groups was 3.39 ± 0.65 vs. 3.31 ± 0.6 months, respectively, with no statistically significant differences (p = 0.77). …”
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Mg-Doped PLA Composite as a Potential Material for Tissue Engineering—Synthesis, Characterization, and Additive Manufacturing
Published 2023“…In this study, we prepared and characterized a Mg/PLA composite as a potential material for direct ink writing (DIW) in 3D printing. The results showed that the addition of Mg has a significant impact on PLA’s thermal and structural properties and has also significantly increased the degradation of PLA. …”
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Hydrodynamic Modelling of Sharjah lagoons (UAE) under Climate Changes
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doctoralThesis