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261
Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway
Published 2021“…SNG treatment increased Bax/Bcl-2 ratio, which contributed to a leaky mitochondrial membrane leading to cytochrome c release accompanied by caspase activation. …”
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262
<i>Asterarcys quadricellulare</i> (Chlorophyceae) protects H9c2 cardiomyoblasts from H<sub>2</sub>O<sub>2</sub>-induced oxidative stress
Published 2022“…Furthermore, total caspase-3 was increased following treatment with the hexanoic extract, suggesting that <i>A. quadricellulare</i> also had anti-apoptotic properties. …”
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263
The genetic basis and the diagnostic yield of genetic testing related to nonsyndromic hearing loss in Qatar
Published 2024“…The prevalence of hereditary hearing loss increases in consanguineous populations, and the prevalence of hearing loss in Qatar is 5.2%. …”
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264
Augmented Reality in Medical Practice: From Spine Surgery to Remote Assistance
Published 2021“…<h3>Background</h3><p dir="ltr">While performing surgeries in the OR, surgeons and assistants often need to access several information regarding surgical planning and/or procedures related to the surgery itself, or the accessory equipment to perform certain operations. …”
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265
Improvement of Kernel Principal Component Analysis-Based Approach for Nonlinear Process Monitoring by Data Set Size Reduction Using Class Interval
Published 2024“…The proposed algorithm has been tested on three tank system pilot plant and Ain El Kebira Cement rotary kiln process. …”
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266
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Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12
Published 2021“…<div><p>The tumour suppressor FBW7 is a substrate adaptor for the E3 ubiquitin ligase complex SKP1-CUL1-F-box (SCF), that targets several oncoproteins for proteasomal degradation. …”
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268
Application of chromium oxide-based redox reactions for hydrogen production via solar thermochemical splitting of water
Published 2020“…The thermodynamic properties required for the computations were obtained from an HSC Chemistry 9.9 software. An increase in thermal reduction (TR) temperature (T<sub>H</sub>) from 1800 K to 2230 K was responsible for the rise in the percentage TR of Cr<sub>2</sub>O<sub>3</sub> (Tr-Cr) from 0% to 100%. …”
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269
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270
Safety and efficacy of ensifentrine in COPD: A systemic review and meta-analysis
Published 2024“…George's Respiratory Questionnaire-C (SGRQ-C) scores (LS mean difference: −1.92; 95 % CI: −3.28 to −0.55). Safety profiles were comparable between the ensifentrine and placebo groups, with no significant increase in treatment-emergent <u>adverse events</u> (TEAEs) (RR: 1.02; 95 % CI: 0.94–1.10). …”
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271
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272
Ratios of Acetaminophen Metabolites Identify New Loci of Pharmacogenetic Relevance in a Genome-Wide Association Study
Published 2022“…Here we propose ratios between related drug metabolites as GWAS phenotypes that can drastically increase power to detect genetic associations between pairs of biochemically related molecules. …”
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273
Graphene wrapped Y<sub>2</sub>O<sub>3</sub> coated LiNi<sub>0.5</sub>Mn<sub>1.5</sub>O<sub>4</sub> quasi-spheres as novel cathode materials for lithium-ion batteries
Published 2021“…Conversely, graphene increases the electrical conductivity, wraps the active particles along an electrically conductive path, and prevents agglomeration. …”
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274
Cost-Benefit Analysis of Antimicrobial Stewardship Program Maturity in Adult Surgical Ward Settings: A Retrospective Study in Qatar
Published 2024“…<h3>Background</h3><p dir="ltr">Implementing Antimicrobial Stewardship (ASP) can result in substantial financial costs. …”
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275
Performance Analysis of Binary and Ternary Blends of Ammonia, Hydrogen, and Diesel in Compression Ignition Engine
Published 2025“…Results show that the BTE increases rapidly from 28% to 38% for the investigated binary blends (with 10% NH<sub>3</sub> to 90%) and 25% to 40% for the investigated ternary blended fuels at engine load from 500 to 2000 rpm, respectively. …”
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276
"Thrombosis takedown, safeguarding your journey": QI project to raise Venous Thromboembolism (VTE) awareness among staff and patients at Hamad International Airport, North Node Cli...
Published 2024“…<h3>Background</h3><p dir="ltr">Venous thromboembolism (VTE) is the underlying cause of 1 in 4 deaths worldwide, the third leading cause of cardiovascular deaths and the number one cause of preventable deaths in hospitalized patients. …”
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277
Pioglitazone Effect on Clinical Outcome and Inflammatory Response in patients with type 2 diabetes mellitus and COVID-19: A Randomized Clinical Trial
Published 2024“…The study had 2 primary outcomes: (1) the incidence of a clinical composite outcome of a) requirement for mechanical ventilation, b) death, c) myocardial damage indicated by Troponin > 3x upper limit of normal range; and 2) an increase in C-reactive protein (CRP). …”
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278
The Qatar Pediatric Emergency Medicine International Conference – Knowledge Translation Successes and Challenges
Published 2024“…This process is aided by a program that includes a large amount of Question and Answer time, case-based studies, and polling of the audience to enhance knowledge acquisition. </p><h3>Findings</h3><p dir="ltr">This annual conference, accredited for Continuing Professional Development (CPD) credits, has become increasingly popular and surpassed 4,400 participants since 2017 (Table 1). …”
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279
Parametric investigation of a chilled water district cooling unit using mono and hybrid nanofluids
Published 2021“…The results of the study show that the use of nanofluids increased the overall heat transfer coefficient in the system by 6.6% when using Al<sub>2</sub>O<sub>3</sub>–TiO<sub>2</sub>/water nanofluids. …”
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280
Obesity in children with Down syndrome: A retrospective review of growth charts and professional recommendations to parents
Published 2024“…<h3>Background</h3><p dir="ltr">Down Syndrome (DS) is the most common genetic disorder. …”