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Circulating exosomal immuno-oncological checkpoints and cytokines are potential biomarkers to monitor tumor response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patien...
منشور في 2023"…We have demonstrated that baseline concentration of exosomal-PD-L1 (p<0.0001), exosomal-PD-L2 (p=0.0413) and exosomal-PD-1 (p=0.0131) from NSCLC patients were significantly higher than their soluble-free forms. Furthermore, the exosomal-PD-L1 was present in all the patients (100%), while only 71% of patients expressed tissue PD-L1. …"
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184
Board independance and the efficiency of internal capital markets
منشور في 2017"…However, the presence of independent directors increases costs associated with information asymmetry and free riding problems. …"
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185
Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases
منشور في 2010"…For example, a few years ago an extrahepatic metastasis effectively eliminated surgical resection, but a combination of chemotherapeutic options and surgical techniques has expanded the indications for resection and increased the population of patients who may benefit.1,2 Neoadjuvant chemotherapy has increased the resectability rate by 11% to 37%.1 Unfortunately, greater than 80% of patients undergoing hepatic resection will have recurrences, mostly within the first 2 years.2 Nonetheless, the only hope for cure is resection, and prior surgical dogma based on the number of lesions, size of the tumor-free resection margin, and presence of resectable extrahepatic disease must be questioned.3- 5 The current standard approach to surgical planning is contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI) for specific tumor characteristics or contraindications to CT.6 Several series showed that focal extrahepatic disease, an isolated pulmonary lesion, can be safely resected, with 5-year survival rates of 29% to 58%.7,8 In 1 series,7 17 of 30 patients required 3 or more resections. …"
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186
Urban Geometry: The Effect of Height Diversity and Buildings Configuration on Thermal Performance and Cooling Load at Urban Scale. A Case Study in Dubai / UAE
منشور في 2018"…However, the previous studies have primarily focused on traditional methods of increasing the shading effect, such as by increasing buildings height / canyon width H/W ratio to provide the required compactness for desired solar access and energy saving target. …"
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187
Serotonin distinctly controls behavioral states in restrained and freely moving Drosophila
منشور في 2023"…<p>When trapped in a physical restraint, animals must select an escape strategy to increase their chances of survival. After falling into an inescapable trap, they react with stereotypical behaviors that differ from those displayed in escapable situations. …"
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188
Gold-Conjugated Curcumin as a Novel Therapeutic Agent against Brain-Eating Amoebae
منشور في 2020"…Balamuthia mandrillaris and Naegleria fowleri are free-living amoebae that cause infection of the central nervous system, granulomatous amoebic encephalitis (GAE) and primary amoebic meningoencephalitis (PAM), respectively. …"
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The distribution of toxic sources in Louisiana
منشور في 1993"…Furthermore, the greater the percentage of blacks in a community, the greater the reductions in discharges. …"
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192
Research on the potential of photovoltaic technologies in reducing energy consumption in an urban mixed use residential community. A Case study for net zero energy community in Dub...
منشور في 2018"…This paper illustrates the many strategies to bridge the deficiency energy gap in three categories; 1) increase PV panel energy production by optimizing the orientation, inclination angle, manual tracking, enhanced microcontrollers and inverters, 2) increase PV panel efficiency from better manufacturers, 3) increase the area of PV panel installation on the building fabric and exploring options beyond the building footprint at the community level. …"
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Error performance of vertical-BLAST over Rayleigh and Nakagami fading channels
منشور في 2003"…Average error burst lengths, average error tree lengths and BER are determined. We also evaluate the effects of different interleaver depths. …"
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195
The antioxidant and anticancer effects of Wild Carrot oil extract
منشور في 2012"…Also, DCOE demonstrated a significant increase in cell death and decrease in cell proliferation. …"
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196
Complex structural contribution of the morphotropic phase boundary in Na0.5Bi0.5TiO3 - CaTiO3 system
منشور في 2019"…The fraction of orthorhombic phase increases gradually with x in the MPB region. Dielectric measurements reveal that the relative permittivity increase with addition of Ca2+. …"
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197
Comparative Study of Several Energy Dissipating Devices
منشور في 2011"…It is concluded that the energy absorbed for a given system decreases with the increase of the R ratio. It is recognized that the highest absorbed energy is obtained in the constrained situation with deformable non-deformable compared to the other situations. …"
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198
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Dynamic 3D imaging of gas hydrate kinetics using synchrotron computed tomography
منشور في 2020"…During hydrate dissociation, bonds between water (host molecules) and gas (guest molecules) break and free gas is released. This paper investigates the evolution of hydrate surface area, pore habit, and tortuosity using in-situ imaging of Xenon (Xe) hydrate formation and dissociation in porous media with dynamic three-dimensional synchrotron microcomputed tomography (SMT). …"
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Experimental and numerical study of different metal contacts for perovskite solar cells
منشور في 2023"…The morphological data confirm the growth of compact, uniform, and defect-free metal films as confirmed by the field emission scanning electron microscopy. …"