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181
The E3 ubiquitin-protein ligase UHRF1 promotes adipogenesis and limits fibrosis by suppressing GPNMB-mediated TGF-β signaling
منشور في 2024"…<p dir="ltr">The E3 ubiquitin-ligase UHRF1 is an epigenetic regulator coordinating DNA methylation and histone modifications. …"
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182
Development and Testing of Novel Drilling Fluids Using Fe2O3 and SiO2 Nanoparticles for Enhanced Drilling Operations
منشور في 2015"…The filtration efficiency was reduced with the increase of the concentration of Fe2O3 nanoparticles which was confirmed by CT scan measurements. …"
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183
Milk Other Than Breast Milk and the Development of Asthma in Children 3 Years of Age. A Birth Cohort Study (2006–2011)
منشور في 2018"…This study indicates that the introduction of MOTBM in the first six months of life is a risk factor for asthma incidence among 3-year old children. This result is important in explaining the benefits of breastfeeding as part of public health interventions to encourage mothers to increase breastfeeding initiation and duration, and avoid the introduction of MOTBM in the first six months after childbirth.…"
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184
How circular economy can reduce scope 3 carbon footprints: Lessons learned from FIFA world cup Qatar 2022
منشور في 2023"…The results also show that electricity, district cooling, and waste generation are the three top contributors of GHG emissions with 35%, 25%, and 21% emissions, respectively. …"
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185
Petrophilic, Fe(III) Reducing Exoelectrogen Citrobacter sp. KVM11, Isolated From Hydrocarbon Fed Microbial Electrochemical Remediation Systems
منشور في 2018"…The electrochemical activities of the strain KVM11 were characterized in a single chamber fuel cell and three electrode electrochemical cells. The inoculation of strain KVM11 amended with acetate and citrate as the sole carbon and energy sources has resulted in an increase in anodic currents (maximum current density) of 212 ± 3 and 359 ± mA/m<sup>2</sup> with respective coulombic efficiencies of 19.5 and 34.9% in a single chamber fuel cells. …"
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186
Over‐expression of the p110β but not p110α isoform of PI 3‐kinase inhibits motility in breast cancer cells
منشور في 2004"…Phosphoinositide 3-kinase (PI 3-kinase) activity is required for growth factor-induced cytoskeletal regulation and cell migration. …"
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187
Additive Manufacturing of Polymer/Mg-Based Composites for Porous Tissue Scaffolds
منشور في 2022"…<div><p>Due to their commercial availability, superior processability, and biocompatibility, polymers are frequently used to build three-dimensional (3D) porous scaffolds. The main issues limiting the widespread clinical use of monophasic polymer scaffolds in the bone healing process are their inadequate mechanical strength and inappropriate biodegradation. …"
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188
Subclavian pseudoaneurysm presenting as partially obstructed airway
منشور في 2023"…Managing the patient's airway posed significant challenges, including the risk of failed intubation, bleeding, and inability to oxygenate the patient.The case highlights the increasing importance of 3-Dimensional reconstruction computerized tomography in accurately diagnosing tracheal narrowing and compression. …"
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189
Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model
منشور في 2022"…Although cardiac contractility was similar to the wild-type control, the ejection fraction was significantly increased in the mypbc3 mutants. At later stages of larval development, the mutants demonstrated an early cardiac phenotype of myocardium remodeling, concurrent cardiomyocyte hyperplasia, and increased ejection fraction as critical processes in HCM initiation to counteract the increased ventricular myocardial wall stress. …"
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190
MicroRNA-24-3p Targets Notch and Other Vascular Morphogens to Regulate Post-ischemic Microvascular Responses in Limb Muscles
منشور في 2020"…Exposure to hypoxia increased miR-24-3p in ECs but not in pericytes. Transfection with a miR-24-3p precursor (pre-miR-24-3p) increased miR-24-3p expression in ECs, reducing the cell survival, proliferation, and angiogenic capacity. …"
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191
Thermoelectric power of (Cu0.5Tl0.5)-1223 superconducting phase added with BaSnO3 nanoparticles
منشور في 2017"…In this study, we report the thermoelectric power (TEP) measurements of Cu0.5Tl0.5Ba2Ca2Cu3O10-δ added with BaSnO3 nanoparticles. BaSnO3 nanoparticles were prepared by chemical co-precipitation method, while (BaSnO3)x/(CuT1)-1223 superconducting samples with 0.00 ≤ x ≤ 1.50 wt% were prepared using the solid-state reaction method. …"
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192
Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia
منشور في 2019"…Curcumin induces apoptosis in B-Pre-ALL cell lines via activation of caspase-8 and truncation of BID. Curcumin treatment increased the ratio of Bax/Bcl-2 and resulted in a leaky mitochondrial membrane that led to the discharge of cytochrome c from the mitochondria to the cytoplasm, the activation of caspase 3 and the cleavage of PARP. …"
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193
Thermal profiles of amorphous solid dispersions (ASD) in 3D printed tablets by fused deposition modelling (FDM): Production of tunable tablet doses
منشور في 2025"…Aptly, there was a 35% increase in solubility and a significant increase (<i>p</i> < 0.05) in dissolution rates of ibuprofen from 3D printed ASD tablets compared to printed tablets of pure ibuprofen. …"
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194
Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways
منشور في 2017"…Western blot analysis revealed a significant decrease in p-Erk, p-Akt, pro-caspase-3 and Bcl-2 and an increase in p53, p21, Bax and PARP proteins. …"
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195
Enhanced nucleate boiling heat transfer on bubble-induced assembly of 3D porous interconnected graphene oxide/silver nanowire hybrid network
منشور في 2022"…<p>Due to an increasing trend of size diminution, integration, and multifunctionality, the heat load on electronic devices is constantly increasing. …"
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196
The effect of graphene on the activation energy of grain growth for the nanocrystalline thermoelectric n-type Bi2Te2.7Se0.3
منشور في 2022"…The activation energy of the pristine Bi2Te2.7Se0.3 alloy is found to be 268 kJ/mol. For the composite samples, a lower graphene weight percentage (0.05 wt.%) increased the activation energy to 270 kJ/mol. …"
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197
Microstructure and Compressive Behavior of Al–Y<sub>2</sub>O<sub>3</sub> Nanocomposites Prepared by Microwave-Assisted Mechanical Alloying
منشور في 2019"…The effect of different levels of yttrium oxide on the microstructural and mechanical properties of the Al–Y<sub>2</sub>O<sub>3</sub> nanocomposites were investigated. The density of the Al–Y<sub>2</sub>O<sub>3</sub> nanocomposites increased with increasing Y<sub>2</sub>O<sub>3</sub> volume fraction in the aluminum matrix, while the porosity decreased. …"
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198
Differential changes in cyclic adenosine 3′-5′ monophosphate (cAMP) effectors and major Ca2+ handling proteins during diabetic cardiomyopathy
منشور في 2023"…Early upregulation of Epac1 transcripts was noted in diabetic hearts at Week 4, followed by increases in Epac2 mRNA, but not protein levels, at Week 12. …"
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199
Intratumoral FoxP3<sup>+</sup>Helios<sup>+</sup> Regulatory T Cells Upregulating Immunosuppressive Molecules Are Expanded in Human Colorectal Cancer
منشور في 2017"…Levels of CD4<sup>+</sup>FoxP3<sup>+</sup>Helios<sup>+</sup> Tregs were significantly increased in the TME. …"
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200
Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation
منشور في 2025"…Prist significantly increases reactive oxygen species (ROS) levels and depletes glutathione (GSH), leading to mitochondrial dysfunction and cytochrome c release. …"