DNAJB3/HSP-40 cochaperone improves insulin signaling and enhances glucose uptake in vitro through JNK repression by Mohamed Abu-Farha (25322)

“…Furthermore, DNAJB3 mediated the PI3K/AKT pathway activation through increasing AKT and AS160 phosphorylation. …”

3D FEM Model on the Parameters’ Influence of EPB-TBM on Settlements of Single and Twin Metro Tunnels During Construction by Masoud Forsat (14158980)

“…<p>The present research exposes the investigation on three-dimensional modeling of the single and twin metro tunnels for the case of the Tehran metro line. …”

Expression of 3-Methylcrotonyl-CoA Carboxylase in Brain Tumors and Capability to Catabolize Leucine by Human Neural Cancer Cells by Eduard Gondáš (18877708)

“…The enrichment of the culture media with a high level of leucine stimulated the production of 3-hydroxybutyrate. When 13C6-leucine was offered, it led to an increased appearance of the heavier citrate isotope with a molar mass greater by two units in the culture media. …”

A novel phosphorylated STAT3 inhibitor enhances T cell cytotoxicity against melanoma through inhibition of regulatory T cells by Abou-Ghazal, Mohamed K.

“…The activation of signal transducer and activator of transcription 3 (STAT3) has been identified as a key mediator that drives the fundamental components of melanoma malignancy, including immune suppression in melanoma patients. …”
Get full text
Get full text
Get full text

Fabrication of Ag₂O/WO₃ based sensors for detection of hydrogen sulfide by Ahmad Al-Sarraj (17151007)

“…</p><p dir="ltr">Moreover, the effect of annealing and comparison with physical mixing was studied and showed that non-annealed Ag-loaded WO₃ produced the best response. The results can be attributed to the decrease in the energy bandgap due to increasing the Ag content and the strong interaction between the Ag and WO₃ and silver to silver oxide transformation at low annealing temperatures. …”

Vitamin D₃ metabolite ratio as an indicator of vitamin D status and its association with diabetes complications by Lina H. M. Ahmed (9571561)

“…<h3>Background</h3><p dir="ltr">Vitamin D deficiency is diagnosed by total serum 25-hydroxyvitamin D (25(OH)D) concentration and is associated with poor health and increased mortality; however, some populations have low 25(OH) D concentrations without manifestations of vitamin D deficiency. …”

Polymer chain dynamics in epoxy based composites as investigated by broadband dielectric spectroscopy by Hassan, Mohammad K.

“…Epoxy networks of the diglycidyl ether of bisphenol A (DGEBA) were prepared using 3,3′- and 4,4′-diaminodiphenyl sulfone isomer crosslinkers. …”
Get full text
Get full text
Get full text

Role of PDE3 and PDE4 for β-adrenergic control of cAMP and ICa,L in adult rat ventricular myocytes by Leroy, Jerome

“…Isoprenaline (Iso, 100 nM, 15 s) induced a transient increase in both [cAMP] i and I Ca,L. PDE3 inhibition with cilostamide (1 μM) neither modified [cAMP] i nor I Ca,L transients, whereas PDE4 inhibition with Ro-201724 (10 μM) prolonged both signals. …”
Get full text
Get full text
Get full text
Get full text

Cost-effective microwave-assisted O3- type sodium-based layered oxide cathode materials for sodium-ion batteries by R.A. Harindi Gayara (17821406)

“…Finally, EIS analysis confirms the capacity fading of the developed materials during the cycling process is essentially due to an increase in the resistance with the increasing number of cycles due to the gradual thickening of formed SEI layer. …”

Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling by Sabah Akhtar (5809925)

“…The SNG-mediated apoptosis appears to be resulted from suppression of the constitutively active STAT3 with a concomitant increase in expression of protein tyrosine phosphatase (SHP-1). …”

A Study on Network Sharing and Radio Resource Management in 3G and Beyond Mobiles Wireless Networks Supporting Heterogeneous Traffic by AlQahtani, S.A.Mahmoud

“…This paper gives an overview of the network sharing options available for 3G and beyond network operators. Sharing of network infrastructure among operators offers an alternative solution to reduce the investment in the coverage phase of WCDMA, allows increased coverage, reduces time to market, and allows earlier user acceptance for WCDMAII and its related services. …”
Get full text
Get full text

The Effect of High Dose Isoflavone Supplementation on Serum Reverse T3 in Euthyroid Men With Type 2 Diabetes and Post-menopausal Women by Thozhukat Sathyapalan (704787)

“…</p><h3>Conclusion</h3><p dir="ltr">Soy isoflavones transiently increased rT3 levels within 3 months though reverted to baseline at 6 months. …”

Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications by Sumama Nuthana Kalva (17302906)

“…<p>This study presents a comprehensive performance evaluation of 3D-printed PLA/WE43 magnesium alloy composites, offering novel insights into composition–structure–function relationships for bone tissue engineering. …”

Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells by Ejlal Abu-El-Rub (5168183)

“…</p><h3>Results</h3><p dir="ltr">Our findings reveal that inhibiting HSP90 with AT13387 reduces RKO cell viability by suppressing proliferation and enhancing Annexin-V expression, indicative of increased apoptosis. …”

OSRA Grant Cycle 3 Public Reports : Project Title: Family Characteristics, Parenting Styles, and Youth Mental Health in Qatar by Livia L. Gilstrap (17425469)

“…<p dir="ltr">This project serves two primary objectives:</p><h3>Objective 1</h3><p dir="ltr">To further validate an Arabic language, youth mental health screening tool in a GCC nation, and 2) to evaluate a unique aspect of GCC family structure and its potential impact on GCC youth. …”

Federated Transfer Learning for Authentication and Privacy Preservation Using Novel Supportive Twin Delayed DDPG (S-TD3) Algorithm for IIoT by Arumugam K (18456690)

“…It is mainly due to a single authentication factor, and the poor adaptation to regular increases in the number of users and different requirements that make the current authentication mechanism suffer a lot in IIoT. …”

A novel inhibitor of STAT3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells by Abou-Ghazal, Mohamed K.

“…Results WP1066 achieved an IC50 of 1.6 μM, 2.3 μM, and 1.5 μM against melanoma cell line A375, B16 and B16EGFRvIII, respectively. …”
Get full text
Get full text
Get full text
Get full text

The effect of doping MoSe₂ by clusters of noble metals on its adsorption for NH₃ by Ahmad I. Ayesh (10188469)

“…Herein, the magnitude of adsorption energy increases and the adsorption distance deceases for NH₃ gas. …”

Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells <i>via</i> Tryptophan 2,3 Dioxygenase by Marta Cecchi (21363581)

“…<p dir="ltr">In addition to its well-established immunosuppressive actions, tryptophan 2,3-dioxygenase (TDO) appears to elicit direct effects on tumor cell function. …”

The impact of nozzle diameter and printing speed on geopolymer-based 3D-Printed concrete structures: Numerical modeling and experimental validation by Shoukat Alim Khan (14778226)

“…<p dir="ltr">3D Concrete Printing (3DCP) is a promising technology with significant advantages for the construction industry, encompassing reduced labor costs, diminished carbon dioxide emissions, enhanced time efficiency, improved user convenience, and design flexibility. …”