Repeat hepatectomy for recurrent colorectal liver metastases is associated with a high survival rate by Andreou, Andreas

“…Background:  The outcome after a repeat hepatectomy for recurrent colorectal liver metastases (CLM) is not well defined. The present study examined the morbidity, mortality and long-term survivals after a repeat hepatectomy for recurrent CLM. …”
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Body surface area and body weight predict total liver volume in Western adults by Vauthey, Jean-Nicolas

“…Computed tomography (CT) is used increasingly to measure liver volume in patients undergoing evaluation for transplantation or resection. …”
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Artificial Intelligence for Detecting and Quantifying Fatty Liver in Ultrasound Images: A Systematic Review by Fahad Muflih Alshagathrh (18427950)

“…Conclusion: AI-supported systems show potential performance increases in detecting and quantifying steatosis, NASH, and liver fibrosis in NAFLD patients. …”

Impaired Liver Size and Compromised Neurobehavioral Activity are Elicited by Chitosan Nanoparticles in the Zebrafish Embryo Model by Haissam Abou-Saleh (497840)

“…Although no single sign of cardiotoxicity was observed upon exposure to 200 mg/L of ChNPs, as judged by heartbeat rate, the corrected QT interval (QTc, which measures the time between the start of the Q wave and the end of the T wave in the heart's electrical cycle), maximum cardiac arrest, and ejection fraction assays, the same dosage elicited the impairment of both liver size (decreased liver size, but without steatosis and lipid yolk retention) and neurobehavioral activity (increased movement under different light conditions). …”

Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer’s disease by Nour K. Majbour (8809316)

“…CSF total α-syn (t-α-syn) significantly increased in the AD group (p < 0.0001) compared to controls, while oligomeric- and phosphorylated-Ser129-α-syn did not change significantly. …”

Targeted Inactivation of Rin3 Increases Trabecular Bone Mass by Reducing Bone Resorption and Favouring Bone Formation by Mahéva Vallet (18456729)

“…</p><p dir="ltr">Correction: Targeted Inactivation of <i>Rin3</i> Increases Trabecular Bone Mass by Reducing Bone Resorption and Favouring Bone Formation <a href="https://doi.org/10.1007/s00223-021-00849-w" target="_blank">https://doi.org/10.1007/s00223-021-00849-w</a>, published online 19 April 2021.…”

Assessment of tropospheric NO₂ concentrations over greater Doha using Sentinel-5 TROPOspheric monitoring instrument (TROPOMI) satellite data: Temporal analysis, 2018–202... by Yasir E. Mohieldeen (22155901)

“…<p dir="ltr">This study presents a temporal evaluation of the tropospheric NO₂ column densities over Greater Doha using TROPOMI satellite data from May 2018 to December 2023, and an assessment of the impact of the preparations and hosting of the FIFA Football World Cup Qatar 2022, on NO₂ levels before, during and after the tournament over Greater Doha. …”

Effects of lipid administration on liver apoptotic signals in a mouse model of total parenteral nutrition (TPN) by Btaiche, Imad

“…Interestingly, we have recently observed an increase in hepatocyte apoptosis with administration of TPN. …”
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Increased MicroRNA Levels in Women With Polycystic Ovarian Syndrome but Without Insulin Resistance: A Pilot Prospective Study by Alexandra E. Butler (6189536)

Neither Neoadjuvant nor Adjuvant Therapy Increases Survival After Biliary Tract Cancer Resection with Wide Negative Margins by Glazer, Evan

“…Immediate resection increased median survival from 42.3 to 53.5 months (p = 0.01). …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells by Shebaby, Wassim N.

“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Efficacy and safety of aldafermin in non-alcoholic steatohepatitis: A systematic review and meta-analysis of randomized controlled trials by Mohamed Mahmoud Marey (18560902)

“…<h3>Background</h3><p dir="ltr">Non-alcoholic steatohepatitis (NASH) is an advanced subtype of non-alcoholic fatty liver disease (NAFLD). NASH prevalence is increasing exponentially and carries a high risk for disease progression, cirrhosis, and liver-related mortality. …”

Novel proteins implicated in lipid metabolism disorders by Nature Research (16552612)

“…</p><p>ANGPTL3 is a protein secreted by the liver, belonging to the angiopoietin-like family of eight proteins. …”

Increased Frequency of Severe Hypoglycemia with the Modified-Release Gliclazide Compared to Glimepiride in Diabetic Older Adults; Propensity Score-Adjusted Analysis by Ahmed Fouad Algendy (18102706)

“…The low doses of both treatments did not show any SHEA cases, while the results with higher doses showed the same pattern of increased risk with gliclazide MR as the principle analysis. …”

Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection? by Abu Saleh Md Moin (6189512)

“…Baseline sNRP1, VEGF and ADAM9 did not differ between T2D and controls and remained unchanged in response to hypoglycaemia. …”

Pathology of the liver in obese and diabetic ob/ob and db/db mice fed a standard or high-calorie diet by Nasser, Selim

“…Non-alcoholic fatty liver disease (NAFLD) is one of the commonest liver diseases in Western countries. …”
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Risk factors for early death due to recurrence after liver resection for hepatocellular carcinoma: Results of a multicenter study by Abdalla, Eddie

“…Of these, 53 (43%) died of recurrence, 30 (24%) of post-operative complications, and 40 (33%) of liver failure/hemorrhage. On multivariateanalysis, tumor size greater than 5 cm (P < 0.02; odds ratio, 3.0), multiple tumors(P < 0.01; odds ratio, 3.3), and greater than 5 mitoses per 10 high-power fields(P < 0.03; odds ratio, 3) were associated with increased risk of early death due torecurrence.Conclusions: These findings enable identification of patients with HCC who are athigh risk for early death due to recurrence following potentially curative resection whomight be candidates for adjuvant therapy trials.…”
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Bevacizumab Improves Pathologic Response and Protects Against Hepatic Injury in Patients Treated With Oxaliplatin-Based Chemotherapy for Colorectal Liver Metastases by Ribero, David

“…However, the addition of bevacizumab to 5FU/OX did not appear to increase the incidence of complete pathologic response (11.3% vs 11.6%; P = .59). …”
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Bound by barriers: demystifying the constraints on an elevated Kuwait-Türkiye co-operation in the defence realm by Ali Bakir (17917703)

“…First, Kuwait is less inclined to enhance its security and defence ties with Türkiye compared to the UAE, Qatar, and Saudi Arabia. …”

Sinusoidal obstruction syndrome and nodular regenerative hyperplasia are frequent oxaliplatin-associated liver lesions and partially prevented by bevacizumab in patients with hepat... by Rubbia-Brandt, Laura

“…Rubbia-Brandt L, Lauwers G Y, Wang H, Majno P E, Tanabe K, Zhu A X, Brezault C, Soubrane O, Abdalla E K, Vauthey J-N, Mentha G & Terris B (2010) Histopathology56, 430–439 Sinusoidal obstruction syndrome and nodular regenerative hyperplasia are frequent oxaliplatin-associated liver lesions and partially prevented by bevacizumab in patients with hepatic colorectal metastasis Aims:  Because of its efficacy, oxaliplatin (OX) is increasingly used as a chemotherapeutic agent in the treatment of colorectal liver metastases (CRLM). …”
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