Dual Targeting of Matrix Metalloproteases and the MAPK Pathway in Acute Myeloid Leukemia Cells Using an MMP-activated anthrax lethal toxin (PrAgL1/LF) حسب Al Saneh, Ahmad

"…Our results demonstrate that vertical inhibition does offer increased potency in comparison to single targeting of the MAPK pathway when working with sensitive cell lines that are dependent on the cascade. …"
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Performance assessment of an integrated absorption cooling-hydrogen liquefaction system using geothermal energy حسب Gadalla, Mohamed

"…The results show that the mass of hydrogen gas pre-cooled by the absorption system per unit mass flow rate of geothermal water flowing through the system (n) and the amount of hydrogen liquefied per unit mass flow rate of geothermal water flowing through the system (y) increase with an increase in the geothermal source temperature. …"
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An improved non-dimensional model of wet-cooling towers حسب QURESHI, BILAL AHMED

"…The first method shows a maximum decrease of 4.4 per cent in error, whereas in the second method, the maximum error was found to be 3.3 and 6.8 per cent when the inlet air was unsaturated and saturated, respectively. …"
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Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells حسب Haykal, Tony

"…Treatment with an A. cherimola seed ethanolic extract promotes a dose- and time-dependent inhibition of the proliferation of various AML cell lines, but not MSCs. Positive Annexin V staining, as well as DNA fragmentation, confirm an increase in apoptotic cell death by upregulating the expression of pro-apoptotic proteins which control both intrinsic and extrinsic pathways of apoptosis. …"
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Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells By Peter Nasr A thesis حسب Nasr, Peter

"…Treatment with an A. cherimola seed ethanolic extract promotes a dose- and time-dependent inhibition of the proliferation of various AML cell lines, but not MSCs. Positive Annexin V staining, as well as DNA fragmentation, confirm an increase in apoptotic cell death by upregulating the expression of pro-apoptotic proteins which control both intrinsic and extrinsic pathways of apoptosis. …"
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Effects of short term genotropin (rgGH) subcutaneous injection on active ghrelin concentration in rat plasma, stomach, kidney & pancreas. (c2007) حسب Haddad, Haytham

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Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021 حسب Letourneau, Ian D

"…Although the global age-standardised incidence rate of appendicitis has steadily decreased between 1990 and 2021, almost half of GBD regions saw an increase of greater than 10% in their age-standardised incidence rates. …"
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Malva pseudolavatera Leaf Extract Promotes ROS Induction Leading to Apoptosis in Acute Myeloid Leukemia Cells In Vitro حسب El Khoury, Marianne

"…Treatment of AML cell lines with M. pseudolavatera methanolic leaf extract showed a dose- and time-dependent inhibition of proliferation and a dose-dependent increase in apoptotic hallmarks such as an increase in phosphatidylserine on the outer membrane leaflet and membrane leakage in addition to DNA fragmentation. …"
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STRADA: Road traffic accident and injury data in Sweden حسب Marie Skyving (10468519)

"…<p dir="ltr">If every driver in Sweden were to obey the speed limits there would be more than 100 lives spared each year. Every reduction of 1 km/h on average speed in the country saves approximately 20 lives per year (SRA 2015). …"

The Global Economic crisis & organisation change: case studies in the UAE حسب Al Hashemi, Khalid

"…All of these elements should tie together in order to assure the existence of the company as a main target & then the expansion of the operation which means an increase in the profit. …"
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Organizational Change Management: A study on the need for a re-structured organization within a functional configuration حسب Al Marzouqi, Abdulla Ibrahim Abdulla

"…Then, critical factors that might lead to choosing one form of structure over the others will be discussed by deciding about how to tie projects to the parent organization and how to organize the project teams. …"
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Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes حسب Maryam Aghadi (17128819)

"…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …"

Targeting human acute myeloid leukemia cells using human recombinant arginase I (Co) - PEG5000 [HuArgl (Co) - PEG5000] - induced arginine depletion. (c2013) حسب Tanios, Rita Farid

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The antioxidant and anticancer effects of Wild Carrot oil extract حسب Shebaby, Wassim Nasri

"…The effect of DCOE on the cell lines exhibited time and dose-dependent responses. …"
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Minimization of the amplitude of the entire span of beams using mass dampers حسب Issa, Jimmy S.

"…Since minimizing the amplitude at one point of the beam might increase it at another point, in this work the maximum amplitude along the entire beam span is minimized. …"
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Do high energy-efficient buildings increase overheating risk in cold climates? Causes and mitigation measures required under recent and future climates حسب Mutasim Baba, Fuad

"…While without adequate ventilation, the overheating risk in high-energy-efficient buildings can be higher than old buildings, where decreasing wall and window U-values and infiltration rate has a greater contribution to the increase of indoor temperature, while decreasing window SHGC has a lower contribution to the decrease in indoor temperature compared to the case with adequate ventilation. …"
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Global, regional and national burden of bladder cancer and its attributable risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of... حسب Saeid Safiri (3713035)

"…Although there was a clear global decrease in the age-standardised death, and DALY rates, some countries experienced an increase in these rates. …"

Cytotoxicity of Anthrax Lethal Toxin to Human Acute Myeloid Leukemia Cells Is Nonapoptotic and Dependent on Extracellular Signal-Regulated Kinase 1/2 Activity حسب Abi-Habib, Ralph J.

"…We tested potency of LeTx on a panel of 11 human AML cell lines. Seven cell lines showed cytotoxic responses to LeTx. …"
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Renewable Energy Consumption and Carbon Emissions: Evidence from an Oil-Rich Economy حسب Shahriyar Mukhtarov (19325662)

"…The results reveal that renewable energy consumption has a negative impact on CO₂ emissions, while real GDP per capita has a positive effect. According to the findings, a 1% increase in renewable energy consumption leads to a 0.26% decrease in consumption-based CO₂ emissions, while a 1% rise in real GDP per capita leads to a 0.46% rise in consumption-based CO₂ emissions. …"

The impact of maternal care on child development حسب Sayour, Nagham

"…Results show that treated children enjoy an increase of 3.6 h per week in the time they spend with their mothers, mainly due to a decrease in the time spent in non-institutional care. …"
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