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221
Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015)
منشور في 2016"…Furthermore, we have attempted to examine the photochemical potential of our metal-organic compound model by combining L-II and L-III in the same metal complex, thus generating four final complexes with differing net charges (from +2 to -4), and examining their activities on a panel of AML cell lines with or without exposure to blue light. Of the four final complexes Ru-II3, Ru-II2-III, Ru-II-III2 and Ru-III3, only Ru-II3 and Ru-II2-III have shown significant activity against all tested cell lines in the dark, whereas photo-activation against ML2 has shown a marked increase of potency of all four complexes, even those shown to be biologically inert in the dark, reaching IC50 values in the nM range. …"
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masterThesis -
222
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223
Characterization of the potency and mechanism of action of a novel dual-selective intermolecularly complemented version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Acute...
منشور في 2023"…Finally, while IMC/LF treatment did not affect the expression of any of the proteases tested (uPAR, MMP2, and MMP9), treatment with IMC/FP59 did affect their expression with significant cytotoxic responses seen only in cells whose uPAR expression was not affected at any time point post-treatment. In this study, we showed for the first time the potency of IMC PrAg variant on AML cell lines, its mode of action, as well as its mechanism of cell death.…"
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masterThesis -
224
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225
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226
Artificial neural network algorithms. (c1999)
منشور في 1999احصل على النص الكامل
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masterThesis -
227
Image coding using entropy-constrained reflected residual vector quantization
منشور في 2002"…Since the RVQ scheme is able to implement very large dimensional vector quantization designs like 16/spl times/16 and 32/spl times/32 VQs, it is found highly successful in extracting linear and non-linear correlation among image pixels. …"
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article -
228
Intelligent Rapidly-Exploring Random Tree Star Algorithm
منشور في 2024احصل على النص الكامل
doctoralThesis -
229
Impacts of On-Grid Solar PV on Distribution Networks and Potential Solutions: A Case Study in the Region of Zahle
منشور في 2025"…Recent years have witnessed an increase in the installation of solar photovoltaic-based distributed generators or PV DGs mainly in countries with high solar potential such as Lebanon. …"
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masterThesis -
230
Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro
منشور في 2016"…The pro-apoptotic effect upon combination of topotecan with andrographolide was further observed using annexin V/PI staining; even though andrographolide alone did not alter cell survival, however, when applied to the cells prior to topotecan treatment, the number of apoptotic cells increased from 16% to 57%. Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…"
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article -
231
The Impact of Sporting Events on Air Pollution: An Empirical Examination of National Football League Games
منشور في 2023"…From this, multiple regression analysis was utilized to estimate whether the number of fans was related to changes in air pollution. (3) Results: The regression models found that Ozone and Nitrogen Dioxide levels increased as more individuals attended NFL games. Additional robustness checks and falsification tests suggest that the average NFL event results in an approximately two-percent increase in Ozone levels. (4) Conclusions: The findings from this study contribute to the literature by providing evidence that highly attended sporting events increase pollution levels in the areas near stadiums. …"
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232
Parallel multi-voltage power minimization in VLSI circuits. (c2013)
منشور في 2013احصل على النص الكامل
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masterThesis -
233
Impact of staying at home measures during COVID-19 pandemic on the lifestyle of Qatar’s population: Perceived changes in diet, physical activity, and body weight
منشور في 2021"…Participants reported increased sitting/reclining time (1.94 h/day mean increase), screen times (2.05 h/day mean increase) with p < 0.001, and decreased exercise time (0.11 h/day mean reduction) with p < 0.001. …"
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234
Pt-doped armchair graphene nanoribbon as a promising gas sensor for CO and CO<sub>2</sub>: DFT study
منشور في 2021"…Moreover, an increase of almost 13 times was observed in the adsorption energy for the case of CO on Pt–H-AGNR. …"
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235
Wild carrot oil extract is selectively cytotoxic to human acute myeloid leukemia cells
منشور في 2015"…In this study, we used Daucus carota oil extract (DCOE) to target acute myeloid leukemia (AML) cells. All the AML cell lines tested were sensitive to the extract while peripheral mononuclear cells were not. …"
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article -
236
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237
ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000]
منشور في 2021"…Secondly, the results also showed in both U251 and A172 cells, an increase in the percentage of the survival of cells co-treated with HuArgI (Co)-PEG5000 and chloroquine; indicating that autophagy is contributing to cell death at late time points in GBM cells. …"
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masterThesis -
238
EEG-Based Semantic Vigilance Level Classification Using Directed Connectivity Patterns and Graph Theory Analysis
منشور في 2020"…Behaviorally, all subjects demonstrated vigilance decrement as reflected by the significant increase in response time and reduced accuracy. The strength and directionality of information flow in the connectivity network by RWTE/PDC and the GTA measures significantly decrease with vigilance decrement, p<0.05. …"
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article -
239
Exploring the Critical Success Criteria and Factors of Adopting Technological Innovation in the U.A.E Public Sectors
منشور في 2016"…The findings support the idea that the U.A.E government spends most of their times to improve the project strategies and deliver the service on the assigned times. …"
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240
Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells
منشور في 2013"…In this study, we target arginine auxotrophy of AML cell lines using human arginase I cobalt-PEG5000. HuArgI(Co)-PEG5000 was cytotoxic to all AML cell lines tested. …"
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article