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261
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Enhanced cellular uptake and photochemotherapeutic potential of a lipophilic strained Ru(II) polypyridyl complex
منشور في 2019"…Complex 2 exhibited 35 times lower cellular concentration relative to complex 1. …"
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article -
264
Hydrophobic Ionic Liquids for Efficient Extraction of Oil from Produced Water
منشور في 2022"…The extraction efficiency was found to increase with increasing cation alkyl chain length from C2 to C10. …"
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article -
265
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266
Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF) 1
منشور في 2015"…PrAgU2/LF was cytotoxic to five out of nine AML cell lines. Cytotoxicity of PrAgU2/LF appeared to be nonapoptotic and was associated with MAPK activation and urokinase activity because all the PrAgU2/LF-sensitive cell lines showed both uPAR expression and high levels of MEK1/2 phosphorylation. …"
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article -
267
Unsustainability in emergent systems
منشور في 2017"…In this paper we present a detailed case study of the passenger road transport system in the Greater Beirut Area (GBA) where we identify the root causes of the major problems facing the system today and over the long-term. …"
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conferenceObject -
268
Parallel Algorithm for Hardware Implementation of Inverse Halftoning
منشور في 2005احصل على النص الكامل
article -
269
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270
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271
Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways
منشور في 2015"…Flow cytometric analysis indicated that both fractions induced sub-G1 phase accumulation and increased apoptotic cell death. Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. …"
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article -
272
Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance
منشور في 2022"…<p>Early-stage detection of leukemia is a critical determinant for successful treatment of the disease and can increase the survival rate of leukemia patients. The factors limiting the current screening approaches to leukemia include low sensitivity and specificity, high costs, and a low participation rate. …"
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273
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
منشور في 2019"…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …"
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274
Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Kefir's anti‑cancer potential was tested on CRC cell lines, Caco‑2 and HT‑29, through cytotoxicity, proliferation, and apoptotic assays. …"
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article -
275
Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres
منشور في 2024"…Cytotoxicity assays on human cell lines showed no toxicity towards cells at concentrations of up to 100 µg ml−1 but exhibited increased toxicity at concentrations exceeding 1000 µg ml−1. …"
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article -
276
Urban Geometry: The Effect of Height Diversity and Buildings Configuration on Thermal Performance and Cooling Load at Urban Scale. A Case Study in Dubai / UAE
منشور في 2018"…Furthermore, building orientation plays a significant role in the thermal performance of the urban block, and it contributes to the total cooling load energy saving of the urban block by 6.6 % at the peak time of cooling demand. Moreover, the research found that the variation in building heights will increase the wind velocity by up to 23 %, and this improvement in air flow affects the outdoor air temperature positively. …"
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277
Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans
منشور في 2024"…In addition to cell lines, we assessed the impact of BTZ in an in vivo setting using Caenorhabditis elegans (C. elegans). …"
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278
Investigating the Therapeutic Effects of Small Molecule Imipridones In Pediatric Neuroblastoma
منشور في 2020"…MYCN expression was significantly abrogated in the IMR-32 cell line with either drug treatment. The protein expression of Sox-2, Oct-4, FABP5 and HMGA1 was significantly reduced whereas cleaved PARP1 and caspase-3 and p-H2AX was increased 48 h after drug treatment in the MYCN-amplified IMR-32 cell line. …"
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masterThesis -
279
Income Tax-Free to Taxed: Assessing the Socioeconomic Impacts of Potential Income Tax in the UAE
منشور في 2025احصل على النص الكامل
doctoralThesis -
280