Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

"…We investigated protein glycation and oxidative damage in skeletal muscle of mice with UCP1 expression under control of the human skeletal actin promoter (HSA-mUCP1) at age 12 weeks (young) and 70 weeks (aged). We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …"
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A Comprehensive Method of Ion Exchange Resins Regeneration and Its Optimization for Water Treatment حسب Al-Asheh, Sameer

"…The strong acidic cation polymeric exchanger resin is commercially called MERCK 104765 cation exchanger IV with capacity greater than 3.2 mmol/ml, while the strong basic anion polymeric exchanger resin is commercially called MERCK 104767 anion exchanger III with capacities greater than 1.0 mmol/ml. …"
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Hemodynamics of small aneurysm pairs at the internal carotid artery حسب Jou, Liang-Der

"…The maximum wall shear stress increases for serial aneurysms, but decreases for parallel aneurysms. Interaction between parallel aneurysms is not significant; however, the proximal aneurysm in serial aneurysms may be subject to a greater rupture risk.…"
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Local Over-Expression of VEGF-DDNDC in the Uterine Arteries of Pregnant Sheep Results in Long-Term Changes in Uterine Artery Contractility and Angiogenesis حسب Abi Nader, Khalil

"…Previously we showed that adenovirus (Ad)-mediated VEGF-A165 expression in the pregnant sheep uterine artery (UtA) increased nitric oxide synthase (NOS) expression, altered vascular reactivity and increased UABF. …"
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Safety and efficacy of ensifentrine in COPD: A systemic review and meta-analysis حسب Ambanna Yappalparvi (21260018)

"…Safety profiles were comparable between the ensifentrine and placebo groups, with no significant increase in treatment-emergent <u>adverse events</u> (TEAEs) (RR: 1.02; 95 % CI: 0.94–1.10). …"

Exaggeration of Non-Culprit Coronary Artery Stenosis in the Setting of Primary Percutaneous Coronary Intervention: A Single Center Observational Study حسب Fahmi Othman (14777506)

"…Compared to PPCI angiograms, the non-PPCI angiograms showed a statistically significant reduction in the percentage of stenosis (71.6± 14.4% vs 64.5± 14.4%, <i>p</i>≤ 0.001), and an increase in minimal luminal diameter (0.82± 0.45 mm vs 1.00± 0.44 mm, <i>p</i>≤ 0.001) of non-culprit lesion. …"

Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes حسب Shadi Nejat (19457212)

"…Male and female KO and WT mice were fed a HF diet (45% kcal fat) for 16 weeks. Body weight was measured biweekly, and a glucose tolerance test (GTT) and insulin tolerance test (ITT) were conducted at week 13 and 14, respectively. …"

Trade Flow and Nation Brand Distance: A Structural Gravity Model Approach حسب AL BESHER, HUDA ISMAIL

"…The NBD is calculated based on Country Brand Strength Index (CBSI) which consists of relative values per capita of the statistical data for five different areas that composite the index, which includes the dimensions of exports, tourism, foreign direct investment, immigration, and government environment. …"
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The global, regional, and national burden of stomach cancer in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease study 2017 حسب Arash Etemadi (330880)

"…The highest age-standardised incidence rates in 2017 were seen in the high-income Asia Pacific (29·5, 28·2–31·0 per 100 000 population) and east Asia (28·6, 27·3–30·0 per 100 000 population) regions, with nearly half of the global incident cases occurring in China. …"

Unveiling the dynamics of the breast milk microbiome: impact of lactation stage and gestational age حسب Parul Singh (191877)

"…</p><h3>Results</h3><p dir="ltr">Our analysis revealed that the microbial communities became increasingly diverse and compositionally distinct as the BM matured. …"

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit Masania (7164239)

"…We investigated protein glycation and oxidative damage in skeletal muscle of mice with UCP1 expression under control of the human skeletal actin promoter (HSA-mUCP1) at age 12 weeks (young) and 70 weeks (aged). We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …"

Stabilization of Pluronic P-105 Micelles with an Interpenetrating Network of N,N-Diethylacrylamide حسب Pruitt, John D.

"…The NNDEA was cross-linked with N,N′-bis(acryoyl)cystamine (BAC), and the degree of micellar stability was determined using dynamic light scattering and the fluorescent probe diphenylhexatriene (DPH).The increased micellar stability was not permanent and disappeared over a time period of days to weeks.…"
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Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 حسب Joan B Soriano (6458528)

"…However, when accounting for ageing and population growth, declines were observed in age-standardised prevalence (14·3% decrease), age-standardised death rates (42·6%), and age-standardised DALY rates (38·2%). …"

MRP4 حسب Abi-Gerges, Aniella

"…Application of ISO (1nM) induced a similar increase in cAMP level in WT and MRP4 KO mice (YFP/CFP: 4.4 ± 0.15 in WT vs 4.1 ± 0.44 in KO cells), whereas cAMP signal was greater in MRP4 KO compared to WT mice after PDE inhibition by IBMX (ISO 1nM + IBMX 300µM: 8.1 ± 0.6 in WT vs 11.8 ± 0.62 in KO cells; p<0.01). …"
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High phosphorus diet mitigates impairments in lipid and glucose metabolism associated with diet-induced obesity in male sprague dawley rats حسب Bassil, Maya

"…Thirty Sprague-Dawley adult male rats (mean weight = 201±3g) were allocated into 3 equal groups receiving either a balanced diet (control), high fat diet with regular P concentration of 0.3% (HF) or high fat, high P (0.9%) diet (HFHP). Study lasted for 12 weeks, during which body weight and food intake were measured biweekly and intraperitoneal glucose tolerance test (IPGTT) was performed at the beginning (week2) and end (week 11) of the study. …"
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Sustainability within interior design curriculum in UAE & impact on design mindset حسب Ibrahim, Dina

"…Moreover, we should minimize the credit hours of the universities’ requirements and increase the core or the major credit hours in order to focus more in the market needs, as the completion out there is really high.…"
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Metabolic profiling of pre-gestational and gestational diabetes mellitus identifies novel predictors of pre-term delivery حسب Ilhame Diboun (3522413)

"…<h3>Background</h3><p dir="ltr">Pregnant women with gestational diabetes mellitus (GDM) or type 2 diabetes mellitus (T2DM) are at increased risks of pre-term labor, hypertension and preeclampsia. …"

Can Ease of Doing Business Shorten the Distance and Attract Foreign Direct Investment حسب AL KHOORI, YOUSUF

"…Abstract Due to the accelerating pace of globalization, Multinational Enterprises (MNEs) have increasingly employed foreign direct investment (FDI) to enter foreign markets. …"
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Artificial Intelligence (AI) based machine learning models predict glucose variability and hypoglycaemia risk in patients with type 2 diabetes on a multiple drug regimen who fast d... حسب Tarik Elhadd (5480393)

"…The addition of electronic health record (ehr) information increased R² to 0.636 and reduced MAE to 26.89 and the time of the day feature further increased R² to 0.768 and reduced MAE to 20.55. …"

Surgical Strategies for Synchronous Colorectal Liver Metastases in 156 Consecutive Patients حسب Bouquet, Antoine

"…Median numbers of CLMs per patient were 1 in the combined, 3 in the classic, and 4 in the reverse strategy group (p = 0.01 classic vs reverse; p < 0.001 reverse vs combined). …"
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