يعرض 361 - 380 نتائج من 425 نتيجة بحث عن '(( greater decrease ) OR ((( (tier OR (line OR les)) increase ) OR ( peer decrease ))))*', وقت الاستعلام: 0.19s تنقيح النتائج
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    Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2... حسب Michael, Brauer

    منشور في 2024
    "…For younger demographics (ie, those aged 0–4 years and 5–14 years), risks such as low birthweight and short gestation and unsafe water, sanitation, and handwashing (WaSH) were among the leading risk factors, while for older age groups, metabolic risks such as high SBP, high body-mass index (BMI), high FPG, and high LDL cholesterol had a greater impact. From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20·7% [13·9–27·7]) and environmental and occupational risks (decrease of 22·0% [15·5–28·8]), coupled with a 49·4% (42·3–56·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. …"
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    article
  7. 367

    Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000–17: analysis for the Global Burden of Disease Stud... حسب Robert C Reiner (5147636)

    منشور في 2020
    "…Findings The greatest declines in diarrhoeal mortality were seen in south and southeast Asia and South America, where 54·0% (95% uncertainty interval [UI] 38·1–65·8), 17·4% (7·7–28·4), and 59·5% (34·2–86·9) of units, respectively, recorded decreases in deaths from diarrhoea greater than 10%. …"
  8. 368

    The Impact of Differentiated Learning Strategies on Student Engagement and Achievement حسب EREKAT, HEBAH DAOUD SALEEM

    منشور في 2025
    "…Studies show that, when done correctly, differentiation increases student performance and involvement. Important practices are flexible groupings, tiered assignments, and a range of assessments. …"
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  9. 369

    Knowledge integration in large-scale organizations and networks – Conceptual overview and operational definition حسب Haddad, Marc

    منشور في 2017
    "…In addition, the increasing scale and scope of organizational arrangements, such as multinational partnerships or multi-tiered prime-supplier arrangements commonly encountered in the aerospace, automotive and other complex product development industries, also give rise to environments of dispersed knowledge resources, thus necessitating the subsequent integration of this knowledge across external boundaries spanning large-scale organizational networks. …"
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    conferenceObject
  10. 370

    Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019 حسب Hmwe Hmwe Kyu (8674014)

    منشور في 2022
    "…During the same period, LRI episodes and deaths in children younger than 15 years were estimated to have decreased, and the greatest decline was observed for LRI deaths in males younger than 5 years (–70·7% [–77·2 to –61·8]). …"
  11. 371

    Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells حسب Bekdash, Amira

    منشور في 2013
    "…In this study, we target arginine auxotrophy of AML cell lines using human arginase I cobalt-PEG5000. HuArgI(Co)-PEG5000 was cytotoxic to all AML cell lines tested. …"
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    article
  12. 372

    The mechanisms of resistance of anthrax lethal toxin (LeTx)-induced cytotoxicity in AML cells. (c2018) حسب Abou Harb, Monica

    منشور في 2018
    "…Our results indicate that vertical inhibition by SCH772984 rendered the resistant cell lines sensitive to the inhibition of the MAPK-pathway and showed an increased cytotoxic effect once used in combination with anthrax lethal toxin compared to the use of anthrax lethal toxin alone.…"
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    masterThesis
  13. 373

    An integrated robust optimisation approach for energy communities utilising green hydrogen and renewable energy sources under dynamic, policy-driven tariff mechanisms for sustainab... حسب Sobhan Dorahaki (20545670)

    منشور في 2025
    "…A novel incentive-driven electricity tariff mechanism is introduced, wherein higher hydrogen export volumes to the upstream grid result in tiered electricity discounts for community members, thereby enhancing energy affordability and encouraging renewable integration. …"
  14. 374

    Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018) حسب El Jawhari, Yassmine

    منشور في 2018
    "…Cytotoxicity of [HuArgI (Co)-PEG5000] was tested on two GBM cell lines, namely A172 and U251. Both cell lines showed increased sensitivity at longer incubation periods of [HuArgI (Co)-PEG5000] treatment with IC50 values in the pM range, a result attributable to the arginine auxotrophy expressed in those two cell lines. …"
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    masterThesis
  15. 375

    Exploring critical factors in referral systems at different health‐care levels حسب Farrukh Jamal (8605026)

    منشور في 2024
    "…<h3>Background</h3><p dir="ltr">A consistent referral system and patient patronage are the primary connections between the three tiers in the healthcare delivery system. Patients were scheduled to visit primary care clinics for the first time. …"
  16. 376

    Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans حسب Kirti S. Prabhu (4246144)

    منشور في 2024
    "…In addition to cell lines, we assessed the impact of BTZ in an in vivo setting using Caenorhabditis elegans (C. elegans). …"
  17. 377

    Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres حسب Radha, Remya

    منشور في 2024
    "…Cytotoxicity assays on human cell lines showed no toxicity towards cells at concentrations of up to 100 µg ml−1 but exhibited increased toxicity at concentrations exceeding 1000 µg ml−1. …"
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    article
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    The Anti-Proliferative and Pro-apoptotic Effect of Topotecan in Combination With Thymoquinone in Acute Myelogenous Leukemia حسب Rizk, Sandra

    منشور في 2014
    "…Topotecan (a novel topoisomerase I inhibitor and a water-soluble camptothecin analog) is active against numerous human tumor cell lines, and has shown promising antineoplastic activity in solid tumors and acute leukemia. …"
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    article
  20. 380

    Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF) 1 حسب Nasser, Selim

    منشور في 2015
    "…PrAgU2/LF was cytotoxic to five out of nine AML cell lines. Cytotoxicity of PrAgU2/LF appeared to be nonapoptotic and was associated with MAPK activation and urokinase activity because all the PrAgU2/LF-sensitive cell lines showed both uPAR expression and high levels of MEK1/2 phosphorylation. …"
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    article