بدائل البحث:
tier » ties (توسيع البحث), tied (توسيع البحث), tie (توسيع البحث)
line » life (توسيع البحث), like (توسيع البحث), link (توسيع البحث)
les » less (توسيع البحث)
tier » ties (توسيع البحث), tied (توسيع البحث), tie (توسيع البحث)
line » life (توسيع البحث), like (توسيع البحث), link (توسيع البحث)
les » less (توسيع البحث)
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Environmental Footprint and Economics of a Full-Scale 3D-Printed House
منشور في 2021احصل على النص الكامل
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365
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366
Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2...
منشور في 2024"…For younger demographics (ie, those aged 0–4 years and 5–14 years), risks such as low birthweight and short gestation and unsafe water, sanitation, and handwashing (WaSH) were among the leading risk factors, while for older age groups, metabolic risks such as high SBP, high body-mass index (BMI), high FPG, and high LDL cholesterol had a greater impact. From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20·7% [13·9–27·7]) and environmental and occupational risks (decrease of 22·0% [15·5–28·8]), coupled with a 49·4% (42·3–56·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. …"
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احصل على النص الكامل
article -
367
Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000–17: analysis for the Global Burden of Disease Stud...
منشور في 2020"…Findings The greatest declines in diarrhoeal mortality were seen in south and southeast Asia and South America, where 54·0% (95% uncertainty interval [UI] 38·1–65·8), 17·4% (7·7–28·4), and 59·5% (34·2–86·9) of units, respectively, recorded decreases in deaths from diarrhoea greater than 10%. …"
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368
The Impact of Differentiated Learning Strategies on Student Engagement and Achievement
منشور في 2025"…Studies show that, when done correctly, differentiation increases student performance and involvement. Important practices are flexible groupings, tiered assignments, and a range of assessments. …"
احصل على النص الكامل
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369
Knowledge integration in large-scale organizations and networks – Conceptual overview and operational definition
منشور في 2017"…In addition, the increasing scale and scope of organizational arrangements, such as multinational partnerships or multi-tiered prime-supplier arrangements commonly encountered in the aerospace, automotive and other complex product development industries, also give rise to environments of dispersed knowledge resources, thus necessitating the subsequent integration of this knowledge across external boundaries spanning large-scale organizational networks. …"
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احصل على النص الكامل
احصل على النص الكامل
conferenceObject -
370
Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019
منشور في 2022"…During the same period, LRI episodes and deaths in children younger than 15 years were estimated to have decreased, and the greatest decline was observed for LRI deaths in males younger than 5 years (–70·7% [–77·2 to –61·8]). …"
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371
Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells
منشور في 2013"…In this study, we target arginine auxotrophy of AML cell lines using human arginase I cobalt-PEG5000. HuArgI(Co)-PEG5000 was cytotoxic to all AML cell lines tested. …"
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احصل على النص الكامل
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372
The mechanisms of resistance of anthrax lethal toxin (LeTx)-induced cytotoxicity in AML cells. (c2018)
منشور في 2018"…Our results indicate that vertical inhibition by SCH772984 rendered the resistant cell lines sensitive to the inhibition of the MAPK-pathway and showed an increased cytotoxic effect once used in combination with anthrax lethal toxin compared to the use of anthrax lethal toxin alone.…"
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masterThesis -
373
An integrated robust optimisation approach for energy communities utilising green hydrogen and renewable energy sources under dynamic, policy-driven tariff mechanisms for sustainab...
منشور في 2025"…A novel incentive-driven electricity tariff mechanism is introduced, wherein higher hydrogen export volumes to the upstream grid result in tiered electricity discounts for community members, thereby enhancing energy affordability and encouraging renewable integration. …"
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374
Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018)
منشور في 2018"…Cytotoxicity of [HuArgI (Co)-PEG5000] was tested on two GBM cell lines, namely A172 and U251. Both cell lines showed increased sensitivity at longer incubation periods of [HuArgI (Co)-PEG5000] treatment with IC50 values in the pM range, a result attributable to the arginine auxotrophy expressed in those two cell lines. …"
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احصل على النص الكامل
احصل على النص الكامل
masterThesis -
375
Exploring critical factors in referral systems at different health‐care levels
منشور في 2024"…<h3>Background</h3><p dir="ltr">A consistent referral system and patient patronage are the primary connections between the three tiers in the healthcare delivery system. Patients were scheduled to visit primary care clinics for the first time. …"
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376
Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans
منشور في 2024"…In addition to cell lines, we assessed the impact of BTZ in an in vivo setting using Caenorhabditis elegans (C. elegans). …"
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377
Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres
منشور في 2024"…Cytotoxicity assays on human cell lines showed no toxicity towards cells at concentrations of up to 100 µg ml−1 but exhibited increased toxicity at concentrations exceeding 1000 µg ml−1. …"
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article -
378
Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
منشور في 2024"…Additionally, the distribution of livebirths across the globe is shifting, with a greater proportion occurring in the lowest-income countries. …"
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احصل على النص الكامل
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379
The Anti-Proliferative and Pro-apoptotic Effect of Topotecan in Combination With Thymoquinone in Acute Myelogenous Leukemia
منشور في 2014"…Topotecan (a novel topoisomerase I inhibitor and a water-soluble camptothecin analog) is active against numerous human tumor cell lines, and has shown promising antineoplastic activity in solid tumors and acute leukemia. …"
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احصل على النص الكامل
article -
380
Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF) 1
منشور في 2015"…PrAgU2/LF was cytotoxic to five out of nine AML cell lines. Cytotoxicity of PrAgU2/LF appeared to be nonapoptotic and was associated with MAPK activation and urokinase activity because all the PrAgU2/LF-sensitive cell lines showed both uPAR expression and high levels of MEK1/2 phosphorylation. …"
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احصل على النص الكامل
احصل على النص الكامل
article