The Candida albicans HWP2 protein is necessary for proper adhesion, biofilm formation and can complement a saccharomyces cerevisiae MUC1 null strain. (c2010) حسب Younes, Samer

احصل على النص الكامل
احصل على النص الكامل

The US Public’s Views of Paradiplomacy, 1988–2024 حسب Paul Musgrave (12982827)

"…I report on a 2024 survey of Americans’ paradiplomacy views that updates a 1988 poll conducted by the federal Advisory Commission on Intergovernmental Relations. I find increased support for paradiplomatic activities, but I also find that the degree of support varies by activities’ objective, demographic characteristics, and partisan identity. …"

Characterizing the Effect of Arginine Deprivation on Autophagic Response in Breast Cancer cells حسب Haidar, Fatemah

"…Residual ASS1 tumor expression corelated with increased metastasis and decreased survival in patient luminal A, Her2+ and triple-negative breast cancer. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Early results of total hip arthroplasty using dual-mobility cup in patients with osteonecrosis of the femoral head حسب Assi, Chahine

"…The majority of these patients are young with high functional demand, and show an increased risk of dislocation following surgery than patients with osteoarthritis. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Humanizing AI in medical training: ethical framework for responsible design حسب Mohammed Tahri Sqalli (18420840)

"…<p dir="ltr">The increasing use of artificial intelligence (AI) in healthcare has brought about numerous ethical considerations that push for reflection. …"

Impact of Charging Electric Vehicles under Different State of Charge Levels and Extreme Conditions حسب Claude Ziad El-Bayeh (17542284)

"…<p dir="ltr">High penetration levels of Plug-in Electric Vehicles (PEVs) could cause stress on the network and might violate the limits and constraints under extreme conditions, such as exceeding power and voltage limits on transformers and power lines. This paper defines extreme conditions as the state of a load or network that breaks the limits of the constraints in an optimization model. …"

Intelligent Rapidly-Exploring Random Tree Star Algorithm حسب Ahmed, Khidir Galal Eldin Khidir

احصل على النص الكامل

Crosstalk between aryl hydrocarbon receptor (AhR) and BCL-2 pathways suggests the use of AhR antagonist to maintain normal differentiation state of mammary epithelial cells during... حسب Abdullah, Al-Dhfyan

"…ResultsActivation of the AhR/CYP1A1 pathway in mice increased EpCAMHigh/CD49fLow CD61+ luminal progenitor-like cells in early tumor formation but not in advanced tumors. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Comparative Effect of Sodium Butyrate and Sodium Propionate on Proliferation, Cell Cycle and Apoptosis in Ovarian Cancer Cells حسب Danaf, Daniella

"…This study aimed to investigate and compare the anti-tumor effects of NaB and NaP in two distinctive ovarian cancer cell lines, SKOV-3 and PA-1. The effect of NaB and NaP on proliferation was assessed in 2D and 3D through MTT assay, colony formation assay, and spheroid hanging drop method. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway حسب Shilpa Kuttikrishnan (3520079)

"…Our study investigated NSP‐B's antitumor effects on MM cell lines (U266 and RPMI8226) and the involved molecular mechanisms. …"

Simulating blood vessel scaffolds حسب Nature Research (16552612)

"…According to their simulations, the amount of shear stress is highest at the endoluminal strut surface, where the stent comes into contact with the inner lining of the vessels, but very low at the areas where blood flows in and out of the device. …"

Evaluation of Estrone Liposomes using Microfluidics for Breast Cancer Therapy حسب Al Bostami, Rouba D.

احصل على النص الكامل

Electric Grid Resilience Enhancement During Natural Disasters: An Optimization-Based UAV Inspection and Dynamic Crew Dispatch Model حسب Serag, Yousef

احصل على النص الكامل

Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation حسب Shilpa Kuttikrishnan (3520079)

"…In this study, we demonstrate that Prist effectively inhibits the proliferation of T-ALL cell lines (Jurkat and Molt 4) by inducing G0/G1 cell cycle arrest and triggering intrinsic and extrinsic caspase-dependent apoptosis. …"

Tumor protease-activated fusion toxins حسب Abi-Habib, Ralph J.

"…In this study, we demonstrate that DTU2GMCSF is highly potent against AML cell lines in vitro and is not toxic to normal cells both in vitro and in vivo. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Protein arginine methyltransferase 5 (PRMT5) activates WNT/β‐catenin signalling in breast cancer cells via epigenetic silencing of DKK1 and DKK3 حسب Harshita Shailesh (14779408)

"…<p></p><div> <p>Protein arginine methyltransferase 5 (PRMT5) activity is dysregulated in many aggressive cancers and its enhanced levels are associated with increased tumour growth and survival. However, the role of PRMT5 in breast cancer remains underexplored. …"

Inositol 1,4,5-Trisphosphate Receptors in Hypertension حسب Ali H. Eid (5461829)

"…This involves a phenotypic switch of VSMCs as well as an alteration of cytoplasmic Ca²⁺ signaling machinery, a phenomena tightly related to the aging process. Several lines of evidence implicate changes in expression/function levels of IP₃R isoforms in the development of hypertension, VSMC phenotypic switch, and vascular aging. …"

Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway حسب Kirti.S. Prabhu (17191231)

"…SNG treatment increased Bax/Bcl-2 ratio, which contributed to a leaky mitochondrial membrane leading to cytochrome c release accompanied by caspase activation. …"

A possible culprit for refractory angina حسب Nature Research (16552612)

"…</p><p>This may implicate lipoprotein(a) as having a causal role in refractory angina, but the findings still need to be confirmed by testing a control group of patients who have coronary heart disease but not refractory angina.</p><p>An increased lipoprotein(a) level is known to be highly heritable, and is believed to promote hardening of the arteries by trapping cholesterol in the inner linings of blood vessels, promoting clot formation, recruiting inflammatory cells, or binding pro-inflammatory phospholipids.…"

The SREBP-dependent regulation of cyclin D1 coordinates cell proliferation and lipid synthesis حسب Arwa Aldaalis (13355328)

"…Consequently, inactivation of SREBP1 in human liver and breast cancer cell lines reduces the expression of cyclin D1 and attenuates Rb phosphorylation. …"