Reply to Comments by Kakkar and Dahiya by Chahine, Elias B.

“…TO THE EDITOR: Chahine, Karaoui, and Mansour1 reviewed the efficacy and safety of bedaquiline in the treatment of adults with pulmonary multidrug-resistant tuberculosis (MDR-TB) and generally agree with the comments made by Kakkar and Dahiya.2 Bedaquiline was approved by the Food and Drug Administration based largely on results from phase 2 studies using sputum conversion as a surrogate marker for efficacy rather than long-term mortality data.2 Bedaquiline was shown to be associated with an unfavorable side effect profile, including an unexplained increased risk of mortality, QT prolongation, and elevated liver function tests.2 However, it is important to acknowledge that bedaquiline is the first novel drug to be approved for the treatment of TB in more than 4 decades and the communities devastated by MDR-TB are in desperate need for more options to manage their patients. …”
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In Vitro and In Vivo Effects of Lebanese Cannabis Oil Against Acute Myeloid Leukemia (AML) by Lteif, Anthony

“…WEHI-3 cells were treated with increasing concentrations of COE to determine the IC50 after 24, 48 and 72-hours post treatment. …”
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Towards electric digital twin grid: Technology and framework review by Md. Mhamud Hussen Sifat (17337913)

“…Thus, the power grid transmission loss and location of the overheated line and power connection missing can be detected in addition decision-making and self-healing can possible. …”

Effects of paternal and chronological age on BEGAIN methylation and its possible role in autism by Ramya Potabattula (4401160)

“…<p dir="ltr">Children from old fathers carry an increased risk for autism spectrum (ASD) and other neurodevelopmental disorders, which may at least partially be mediated by paternal age effects on the sperm epigenome. …”

The effect of StarD13 on colorectal cancer proliferation and invasion. (c2013) by Nasrallah, Anita I.

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ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000] by Abdel Khalek, Maya

“…In this study, we examine the mechanism of HuArgI (Co)-PEG5000-induced cell death in both partially and completely auxotrophic GBM cell lines. Our results first showed a significant increase in HuArgI (Co)-PEG5000 treated cells for both U251 and A172 in autophagosome formation; suggesting activation of autophagy in response to arginine deprivation. …”
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Expanding the donor pool by Ramos, Emilio

“…In 1990, one-year graft survival rates were about 70%; by 2000, they were greater than 90% (United States Renal Data System, 2001). …”
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Phase II National Study: Job Satisfaction and Workplace Environment Among Community Pharmacists in Lebanon: Pre and Post Economic Crisis by Salaheddin, Amira Talaat

“…Average weekly working hours decreased from 59.2 hours in Phase 1 to 49.8 hours in Phase II. …”
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Driving and hypoglycemia by Stephen Beer (5480411)

“…Hypoglycemia has been associated with cardiac arrhythmia, a decreased ability to drive and driving mishap. Recent meta-analysis of 15 studies showed a risk road traffic collisions (RTC) of 12-19% greater than general populations. …”

A Case Study to Identify the Hindrances to Widespread Adoption of Electric Vehicles in Qatar by Amith Khandakar (14151981)

“…<p dir="ltr">The adoption of electric vehicles (EVs) have proven to be a crucial factor to decreasing the emission of greenhouse gases (GHG) into the atmosphere. …”

Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications by Jingxuan Shan (4711089)

“…High expression of <i>CCL5</i> in breast tumors was significantly associated with an increased OVS in all BC patients, but particularly in TNBC/Basal-like patients. …”

Effect of national culture on the design of management control systems of multinational enterprises by Elgammal, Walid

“…This kind of research has gained increasing prominence, as it is important to the business community. …”
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Effect of phosphorus supplementation on weight gain and waist circumference of overweight/obese adults by Bassil, MS

“…Methods: This is a double-blind, randomized, placebo-controlled trial of 63 adults aged 18–45 years with a body mass index (BMI) of greater than or equal to25 kg m−2 and normal kidney function at the American University of Beirut. …”
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Influence of natural gas composition on adsorption in calcite Nanopores: A DFT study by Elkhansa Elbashier (14152815)

“…Additionally, in all cases, CO₂ has a greater affinity to the surface than CH₄; thus, it is more affected by the surface curvature and energy. …”

A Design Study for Multivariable Feedback Control For a Variable Speed Wind Turbine by AL AQRA, MELAD BAHJAT ABDELAZIZ

“…Electrical energy consumption is dramatically increasing due to industry developments and expanding of urban areas. …”
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CYBER-ATTACKS AND DATA INTEGRITY CONCERNS CRIPPLE LARGE PARTS OF THE INTERNET ON BANKING by AL BLOUSHI, MANAL

“…The use of the internet in the banking sector is increased day by day. Most of the activities now are done with the help of the internet. …”
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Exploring the Impact of Technology-Enabled Pedagogies on the Effectiveness of Students’ Learning by Fatima, Syeda Kauser

“…Anchored in constructivist learning theories, which emphasize active, inquiry-based learning and authentic assessments, the study examines the impact of immersive technologies like virtual and augmented reality, as well as data-driven instruction on enhancing educational outcomes. …”
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Fluorescein angiography versus superimposed OCT-guided macular laser photocoagulation by Kozak, Igor

“…The area of dye leakage on FA and increased retinal thickness on OCT on the same eye was measured using Heidelberg Explorer software. …”
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Sleeping habits during COVID-19 induced confinement: A study from Jordan by Mahmoud A. Alomari (14780446)

“…Young participants were more likely to experience sleeping disturbance than older ones (p < 0.05). …”

A Fully Optical Laser Based System for Damage Detection and Localization in Rail Tracks Using Ultrasonic Rayleigh Waves: A Numerical and Experimental Study by Masurkar, Faeez

“…First, the noise and unwanted wave packets increase with the increase in the time window and the inspection length. …”
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