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341
Characterizing the Effect of Arginine Deprivation on Autophagic Response in Breast Cancer cells
Published 2021“…Residual ASS1 tumor expression corelated with increased metastasis and decreased survival in patient luminal A, Her2+ and triple-negative breast cancer. …”
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masterThesis -
342
Reply to Comments by Kakkar and Dahiya
Published 2014“…TO THE EDITOR: Chahine, Karaoui, and Mansour1 reviewed the efficacy and safety of bedaquiline in the treatment of adults with pulmonary multidrug-resistant tuberculosis (MDR-TB) and generally agree with the comments made by Kakkar and Dahiya.2 Bedaquiline was approved by the Food and Drug Administration based largely on results from phase 2 studies using sputum conversion as a surrogate marker for efficacy rather than long-term mortality data.2 Bedaquiline was shown to be associated with an unfavorable side effect profile, including an unexplained increased risk of mortality, QT prolongation, and elevated liver function tests.2 However, it is important to acknowledge that bedaquiline is the first novel drug to be approved for the treatment of TB in more than 4 decades and the communities devastated by MDR-TB are in desperate need for more options to manage their patients. …”
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343
Efficiency of commercial banks in Lebanon
Published 2008“…The stochastic production and cost function estimates show that bank level inefficiency effects decreases with time and increases with number of branches, employees per branch, and ratio of staff to operating expenses.…”
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344
CEO gender and managerial entrenchment
Published 2020“…We find that the presence of female CEO decreases the turnover-performance sensitivity, increases the E-index, and inflates CEO compensation. …”
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345
The Effect of Auditor Characteristics on the Quality of Segment Disclosures of Diversified Firms
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doctoralThesis -
346
Local arterial vasoconstriction induced by octreotide in patients with cirrhosis
Published 2000“…Octreotide probably has a facilitating effect over vasoconstrictors increased in chronic liver diseases…”
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347
Dietary Trichosporon mycotoxinivoron modulates ochratoxin-A induced altered performance, hepatic and renal antioxidant capacity and tissue injury in broiler chickens
Published 2021“…The serum concentrations of alanine aminotransferase (ALT) and urea were significantly increased, and these observations were further supported by degenerative changes and increased relative weights of liver and kidneys. …”
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348
Breast cancer cells and bone marrow mesenchymal stromal cells
Published 2017“…While co-culture assays with SaOS-2 increased the expression of osteoblastic markers in MCF-7 cells, SaOS-2 cell conditioned medium increased the expression of RANKL, PTHrP, VEGF and NOGGIN in MCF-7 cells. …”
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349
Regulative Loop between β-catenin and Protein Tyrosine Receptor Type γ in Chronic Myeloid Leukemia
Published 2020“…Furthermore, we demonstrated that the increased expression of β-catenin in PTPRG-negative CML cell lines correlates with DNA (cytosine-5)-methyl transferase 1 (DNMT1) over-expression, which is responsible for PTPRG promoter hypermethylation, while its inhibition or down-regulation correlates with PTPRG re-expression. …”
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350
Targeting of lactate dehydrogenase C dysregulates the cell cycle and sensitizes breast cancer cells to DNA damage response targeted therapy
Published 2021“…Silencing LDHC in four breast cancer cell lines significantly increased the presence of giant cells, nuclear aberrations, DNA damage, and apoptosis. …”
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351
Phenotypic and Proteomic characterization of Clinical Candida albicans isolates resistant to Fluconazole
Published 2021“…Our results showed that resistant isolates had increase ergosterol content, and a slight increase in chitin deposition leading to resistance, but were on average attenuated in virulence compared with sensitive isolates. …”
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masterThesis -
352
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353
The global, regional, and national burden of oesophageal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global...
Published 2020“…Oesophageal cancer caused 9·78 million (9·53–10·03) DALYs, with an age-standardised rate of 120 (117–123) per 100 000 population. Between 1990 and 2017, age-standardised incidence decreased by 22·0% (18·6–25·2), mortality decreased by 29·0% (25·8–32·0), and DALYs decreased by 33·4% (30·4–36·1) globally. …”
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354
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355
Early results of total hip arthroplasty using dual-mobility cup in patients with osteonecrosis of the femoral head
Published 2018“…The majority of these patients are young with high functional demand, and show an increased risk of dislocation following surgery than patients with osteoarthritis. …”
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356
The Activation Kinetics and Crosstalk of RhoGTPases
Published 2020“…Using this technique, we are studying the crosstalk of Rho GTPases in different cell lines, with a focus on RhoA, RhoC, Cdc42 and Rac1. …”
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masterThesis -
357
Humanizing AI in medical training: ethical framework for responsible design
Published 2023“…<p dir="ltr">The increasing use of artificial intelligence (AI) in healthcare has brought about numerous ethical considerations that push for reflection. …”
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358
Impact of Charging Electric Vehicles under Different State of Charge Levels and Extreme Conditions
Published 2021“…<p dir="ltr">High penetration levels of Plug-in Electric Vehicles (PEVs) could cause stress on the network and might violate the limits and constraints under extreme conditions, such as exceeding power and voltage limits on transformers and power lines. This paper defines extreme conditions as the state of a load or network that breaks the limits of the constraints in an optimization model. …”
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359
Intelligent Rapidly-Exploring Random Tree Star Algorithm
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doctoralThesis -
360
Acute exposure to cigarette smoking followed by myocardial infarction aggravates renal damage in an In vivo mouse model
Published 2017“…Moreover, S+MI group, but not S alone, showed a significant increase in the expression of connective tissue growth factor (CTGF) and fibrotic proteins fibronectin (FN) and α-smooth muscle actin (SMA), in comparison to controls, in addition to a significant increase in mRNA levels of IL-6 and TNF-α inflammatory markers. …”
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