Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015) by Azar, Daniel Fadi

“…Furthermore, we have attempted to examine the photochemical potential of our metal-organic compound model by combining L-II and L-III in the same metal complex, thus generating four final complexes with differing net charges (from +2 to -4), and examining their activities on a panel of AML cell lines with or without exposure to blue light. Of the four final complexes Ru-II3, Ru-II2-III, Ru-II-III2 and Ru-III3, only Ru-II3 and Ru-II2-III have shown significant activity against all tested cell lines in the dark, whereas photo-activation against ML2 has shown a marked increase of potency of all four complexes, even those shown to be biologically inert in the dark, reaching IC50 values in the nM range. …”
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Wild carrot oil extract is selectively cytotoxic to human acute myeloid leukemia cells by Tawil, Mirna

“…In this study, we used Daucus carota oil extract (DCOE) to target acute myeloid leukemia (AML) cells. All the AML cell lines tested were sensitive to the extract while peripheral mononuclear cells were not. …”
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Characterization of the potency and mechanism of action of a novel dual-selective intermolecularly complemented version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Acute... by Farhat, Mirna

“…However, given that MMP9 was found not to be expressed in the sensitive cell lines, we were able to exclude its expression as a requirement for cytotoxicity. …”
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Exam scheduling algorithms. (c1999) by Mikati, Ziad

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The Gulf Cooperation Council states: Crystallization of the regional cooperation and alliances amid dwindling resources by Evren Tok (14779270)

“…<p dir="ltr">The Gulf Cooperation Council (GCC) states can be divided into two main camps in terms of hydrocarbon endowment per capita which can partially account for differences in policy directions. …”

Editorial of Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine by Salman M. Toor (8854751)

“…<p dir="ltr">The global burden of influenza-associated respiratory mortality is higher than previous estimates, with over 0.6 million deaths per year and additional mortality rates attributed to non-respiratory but influenza-related illnesses [1]. …”

The effects of daucus carota extracts on different body functions, inflammation, induced gastric ulcer in rats and bacterial growth. (c2005) by Abdallah, Katia Wehbe

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Impacts of On-Grid Solar PV on Distribution Networks and Potential Solutions: A Case Study in the Region of Zahle by Korkmaz, Jessica

“…Recent years have witnessed an increase in the installation of solar photovoltaic-based distributed generators or PV DGs mainly in countries with high solar potential such as Lebanon. …”
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Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro by Rizk, Sandra

“…The pro-apoptotic effect upon combination of topotecan with andrographolide was further observed using annexin V/PI staining; even though andrographolide alone did not alter cell survival, however, when applied to the cells prior to topotecan treatment, the number of apoptotic cells increased from 16% to 57%. Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…”
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Global, regional, and national burden of upper respiratory infections and otitis media, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021 by Sirota, Sarah Brooke

“…The mortality rate of URIs in 2021 was 0·2 per 100 000 (0·1 to 0·5), a decrease of 64·2% (–84·6 to –43·4) from 1990, when the mortality rate was 0·7 per 100 000 (0·2 to 1·1). …”
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Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells by Bekdash, Amira

“…In this study, we target arginine auxotrophy of AML cell lines using human arginase I cobalt-PEG5000. HuArgI(Co)-PEG5000 was cytotoxic to all AML cell lines tested. …”
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Evaluation of waterpipe smoke toxicity in C57BL/6 mice model by Abi-Gerges, Aniella

“…Additionally, severe significant DNA damages (p < 0.05) were reported in the lungs, kidneys, bone marrow and liver of waterpipe-exposed animals, using MTS and COMET assays. …”
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Cucurbita pepo inhibits benign prostatic hyperplasia induced by testosterone in sprague-dawley rats. (c2011) by Nawfal, Tania M.

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Catalytic Transformation Of C-7-C9 Methyl Benzenes Over USY-Based FCC Zeolite Catalyst by Al-Khattaf, S

“…The sequence of reactivity of the three alkyl benzenes was found to decrease as the number of methyl group per benzene ring decreases, as follows: 1,2,4-trimethylbenzene > m-xylene > toluene. …”
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Solar water heating in Lebanon by Houri, Ahmad

“…Simplified initial estimates indicate a payback period of 4–5 years while advanced mathematical models (RETScreen) indicate that the most advanced evacuated tube technology has a payback period of less than 9 years at current market prices. With decreasing cost per square meter of installed collectors, payback periods are expected to rapidly decrease. …”
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ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000] by Abdel Khalek, Maya

“…In this study, we examine the mechanism of HuArgI (Co)-PEG5000-induced cell death in both partially and completely auxotrophic GBM cell lines. Our results first showed a significant increase in HuArgI (Co)-PEG5000 treated cells for both U251 and A172 in autophagosome formation; suggesting activation of autophagy in response to arginine deprivation. …”
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The Extent to Which Schools with Mechanistic Structures and their Job Characteristics are Likely to Generate Teachers’ Organisational Commitment: Study Conducted in a Private Schoo... by Mansour, Hadi

“…Staff are motivated due to their perception of the importance of their roles however an increase in autonomy and authority in decision making as well as diversifying the job skills used during teaching could further increase motivation. …”
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The SREBP-dependent regulation of cyclin D1 coordinates cell proliferation and lipid synthesis by Arwa Aldaalis (13355328)

“…Consequently, inactivation of SREBP1 in human liver and breast cancer cell lines reduces the expression of cyclin D1 and attenuates Rb phosphorylation. …”

Portal Vein Embolization in Hilar Cholangiocarcinoma by Palavecino, Martin

“…In patients whose standardized future liver remnant is less than or equal to 20% of total liver volume, portal vein embolization (PVE) should be performed. …”
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Drone Based Outdoor Insulator Inspection by Waleed, Danial

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