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261
Regulative Loop between β-catenin and Protein Tyrosine Receptor Type γ in Chronic Myeloid Leukemia
Published 2020“…Furthermore, we demonstrated that the increased expression of β-catenin in PTPRG-negative CML cell lines correlates with DNA (cytosine-5)-methyl transferase 1 (DNMT1) over-expression, which is responsible for PTPRG promoter hypermethylation, while its inhibition or down-regulation correlates with PTPRG re-expression. …”
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262
Targeting of lactate dehydrogenase C dysregulates the cell cycle and sensitizes breast cancer cells to DNA damage response targeted therapy
Published 2021“…Silencing LDHC in four breast cancer cell lines significantly increased the presence of giant cells, nuclear aberrations, DNA damage, and apoptosis. …”
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263
Phenotypic and Proteomic characterization of Clinical Candida albicans isolates resistant to Fluconazole
Published 2021“…Our results showed that resistant isolates had increase ergosterol content, and a slight increase in chitin deposition leading to resistance, but were on average attenuated in virulence compared with sensitive isolates. …”
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masterThesis -
264
The global, regional, and national burden of oesophageal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global...
Published 2020“…Oesophageal cancer caused 9·78 million (9·53–10·03) DALYs, with an age-standardised rate of 120 (117–123) per 100 000 population. Between 1990 and 2017, age-standardised incidence decreased by 22·0% (18·6–25·2), mortality decreased by 29·0% (25·8–32·0), and DALYs decreased by 33·4% (30·4–36·1) globally. …”
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265
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266
Early results of total hip arthroplasty using dual-mobility cup in patients with osteonecrosis of the femoral head
Published 2018“…The majority of these patients are young with high functional demand, and show an increased risk of dislocation following surgery than patients with osteoarthritis. …”
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267
The Activation Kinetics and Crosstalk of RhoGTPases
Published 2020“…Using this technique, we are studying the crosstalk of Rho GTPases in different cell lines, with a focus on RhoA, RhoC, Cdc42 and Rac1. …”
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masterThesis -
268
Humanizing AI in medical training: ethical framework for responsible design
Published 2023“…<p dir="ltr">The increasing use of artificial intelligence (AI) in healthcare has brought about numerous ethical considerations that push for reflection. …”
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269
Impact of Charging Electric Vehicles under Different State of Charge Levels and Extreme Conditions
Published 2021“…<p dir="ltr">High penetration levels of Plug-in Electric Vehicles (PEVs) could cause stress on the network and might violate the limits and constraints under extreme conditions, such as exceeding power and voltage limits on transformers and power lines. This paper defines extreme conditions as the state of a load or network that breaks the limits of the constraints in an optimization model. …”
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270
Intelligent Rapidly-Exploring Random Tree Star Algorithm
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doctoralThesis -
271
Acute exposure to cigarette smoking followed by myocardial infarction aggravates renal damage in an In vivo mouse model
Published 2017“…Moreover, S+MI group, but not S alone, showed a significant increase in the expression of connective tissue growth factor (CTGF) and fibrotic proteins fibronectin (FN) and α-smooth muscle actin (SMA), in comparison to controls, in addition to a significant increase in mRNA levels of IL-6 and TNF-α inflammatory markers. …”
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272
The burden of unintentional drowning: global, regional and national estimates of mortality from the Global Burden of Disease 2017 Study
Published 2020“…Global age-standardised mortality rates decreased 57.4%, from 9.3 (8.5 to 10.0) in 1990 to 4.0 (3.8 to 4.1) per 100 000 per annum in 2017. …”
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273
The Jordan and Litani rivers in the Middle East. (c1996)
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masterThesis -
274
A component analysis of positive behaviour support plans
Published 2012“…Conclusion Only treatment acceptability was found to be related to decreases in behavioural frequency. No single intervention component was found to have a greater association with reductions in challenging behaviour…”
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275
Unmasking Hidden Gluten: Evaluating the Compliance of Gluten-Free Products and Consumer Exposure in Lebanon
Published 2025“…Strengthened regulatory surveillance, dedicated production lines for high-risk categories, and targeted consumer education must be enforced to safeguard medically vulnerable populations and uphold ethical standards.…”
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masterThesis -
276
COPE for adolescent Syrian refugees in Lebanon: a brief cognitive–behavioral skill-building intervention to improve quality of life and promote positive mental health
Published 2018“…Lebanon has the highest per-capita concentration of refugees worldwide. …”
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277
Comparative Effect of Sodium Butyrate and Sodium Propionate on Proliferation, Cell Cycle and Apoptosis in Ovarian Cancer Cells
Published 2024“…Finally, the mode of cell death exerted by NaB and NaP was through apoptosis, as seen by the increased percentage of early/late apoptotic cells and the elevation of Bax/Bcl-2 ratio in treated cells. …”
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masterThesis -
278
Identification of Cancer Stem Cells in Human Gastrointestinal Carcinoid and Neuroendocrine Tumors
Published 2011“…We sought to identify gastrointestinal neuroendocrine CSCs (N-CSCs) in surgical specimens and a NET cell line and to characterize novel N-CSC therapeutic targets. …”
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279
Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway
Published 2023“…Our study investigated NSP‐B's antitumor effects on MM cell lines (U266 and RPMI8226) and the involved molecular mechanisms. …”
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280
Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells <i>via</i> Tryptophan 2,3 Dioxygenase
Published 2022“…Moreover, dex stimulates spherogenesis of both cell lines, which is mediated by TDO, evident by its suppression with 680C91, a TDO inhibitor. …”