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41
Visitors off the trail: Impacts on the dominant plant, bryophyte and lichen species in alpine heath vegetation in sub-arctic Sweden
Published 2021“…With a greater decrease in taller forbs and shrubs than in graminoids and prostrate plants, a greater decrease in lichen than in bryophyte species, and a change in vegetation composition. …”
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Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
Published 2023“…</p><h3>Conclusion</h3><p dir="ltr">To our knowledge this is the first report of the stable non-lethal increase of SLFN11 expression in a cancer cell line. …”
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Malva pseudolavatera Leaf Extract Promotes ROS Induction Leading to Apoptosis in Acute Myeloid Leukemia Cells in Vitro
Published 2020“…Treatment of AML cell lines with M. pseudolavatera methanolic leaf extract showed a dose- and time-dependent inhibition of proliferation and a dose-dependent increase in apoptotic hallmarks such as an increase in phosphatidylserine on the outer membrane leaflet and membrane leakage in addition to DNA fragmentation. …”
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44
Dual Targeting of Matrix Metalloproteases and the MAPK Pathway in Acute Myeloid Leukemia Cells Using an MMP-activated anthrax lethal toxin (PrAgL1/LF)
Published 2020“…Our results demonstrate that vertical inhibition does offer increased potency in comparison to single targeting of the MAPK pathway when working with sensitive cell lines that are dependent on the cascade. …”
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Drug Resistance Induction and Phenotypic and Genotypic Characterization of a Candida albicans Drug Sensitive Isolate
Published 2023“…An interesting aspect of our study is the increase in the number of mutations in key genes with a sequential increase of drug selective pressures as the organism tries to increase its odds of adapting to an inhospitable environment. …”
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47
Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017)
Published 2017“…It is also important to mention that we noticed an increase in the percent of surviving cells among completely auxotrophic cell lines postaddition of citrulline at 72, 96 and 120 hours of drug incubation. …”
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48
Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells
Published 2019“…Treatment with an A. cherimola seed ethanolic extract promotes a dose- and time-dependent inhibition of the proliferation of various AML cell lines, but not MSCs. Positive Annexin V staining, as well as DNA fragmentation, confirm an increase in apoptotic cell death by upregulating the expression of pro-apoptotic proteins which control both intrinsic and extrinsic pathways of apoptosis. …”
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49
Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells By Peter Nasr A thesis
Published 2020“…Treatment with an A. cherimola seed ethanolic extract promotes a dose- and time-dependent inhibition of the proliferation of various AML cell lines, but not MSCs. Positive Annexin V staining, as well as DNA fragmentation, confirm an increase in apoptotic cell death by upregulating the expression of pro-apoptotic proteins which control both intrinsic and extrinsic pathways of apoptosis. …”
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50
Is board compensation excessive?
Published 2017“…Based on this, we then calculate whether directors of corporate boards are over- or undercompensated. On average, we find greater evidence of over- rather than undercompensation. …”
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Malva pseudolavatera Leaf Extract Promotes ROS Induction Leading to Apoptosis in Acute Myeloid Leukemia Cells In Vitro
Published 2020“…Treatment of AML cell lines with M. pseudolavatera methanolic leaf extract showed a dose- and time-dependent inhibition of proliferation and a dose-dependent increase in apoptotic hallmarks such as an increase in phosphatidylserine on the outer membrane leaflet and membrane leakage in addition to DNA fragmentation. …”
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52
The new accounting standard IFRS 9 and its impact on how banks should provision for credit losses
Published 2019“…Moreover, IFRS 9 impacts many capital ratios such as Capital Adequacy Ratio (CAR) and Common Equity Tier 1 (CET 1). The findings and results of the interview questions were that the new standard will impact the provision part of the banks but this impact will not be dramatic. …”
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53
Scrambled Prime Key Encryption
Published 2018“…Nevertheless, but the fast increase in computers' speed may threaten these algorithms. …”
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54
Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes
Published 2022“…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …”
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The antioxidant and anticancer effects of Wild Carrot oil extract
Published 2012“…The effect of DCOE on the cell lines exhibited time and dose-dependent responses. …”
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57
Minimization of the amplitude of the entire span of beams using mass dampers
Published 2017“…Since minimizing the amplitude at one point of the beam might increase it at another point, in this work the maximum amplitude along the entire beam span is minimized. …”
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58
Do high energy-efficient buildings increase overheating risk in cold climates? Causes and mitigation measures required under recent and future climates
Published 2022“…While without adequate ventilation, the overheating risk in high-energy-efficient buildings can be higher than old buildings, where decreasing wall and window U-values and infiltration rate has a greater contribution to the increase of indoor temperature, while decreasing window SHGC has a lower contribution to the decrease in indoor temperature compared to the case with adequate ventilation. …”
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Determinants of research productivity and efficiency among the Arab world’s accredited business schools
Published 2023“…These findings offer valuable insights for the region’s business schools to benchmark their research performance and gain a nuanced understanding of the factors that contribute to increased research productivity and impact. The study concludes that business schools in the Arab region must continue to enhance their publication rates in top-tier journals, foster improved international collaborations, and implement new research incentive schemes and excellence initiatives that recognize and reward high-quality research.…”
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Cytotoxicity of Anthrax Lethal Toxin to Human Acute Myeloid Leukemia Cells Is Nonapoptotic and Dependent on Extracellular Signal-Regulated Kinase 1/2 Activity
Published 2013“…We tested potency of LeTx on a panel of 11 human AML cell lines. Seven cell lines showed cytotoxic responses to LeTx. …”
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