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Therapeutic Impact of P-PENT, P-HEX and 5CLSS (IV) Platinum (IV) complexes on Acute Myeloid Leukemia in vitro and in vivo
Published 2025“…All three complexes caused significant cytotoxicity with IC50 values of 0.12, 0.070, and 0.12 μM for 5CLSS(IV), PPENT, and P-HEX, respectively. A significant increase in ROS production was also observed upon cell treatment with the complexes. …”
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102
A Systematic Approach to the Design and Characterization of a Smart Insole for Detecting Vertical Ground Reaction Force (vGRF) in Gait Analysis
Published 2020“…., of the current gait analysis techniques have made them unfeasible for individual use. This led to an increase in research interest in developing smart insoles where wearable sensors can be employed to detect vertical ground reaction forces (vGRF) and other gait variables. …”
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103
SARS‐CoV‐2 infection and effects of age, sex, comorbidity, and vaccination among older individuals: A national cohort study
Published 2023“…Risk of infection varied minimally by age and sex but increased significantly with coexisting conditions. …”
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104
Preputial balanitis xerotica obliterans shortly after hand, foot and mouth disease in a 5-year-old boy: Coincidence or consequence?
Published 2021“…To the best of our knowledge, no cases of hand, foot, and mouth disease (HFMD) associated with BXO have been reported so far. A 5-year-old boy was referred to our department with an 8-month history of a painless progressive inability to retract the foreskin of the glans penis.…”
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105
SARS‐CoV‐2 omicron variant may present with severe sickle cell painful crisis: A report of two cases
Published 2023“…Patients with sickle cell disease infected with SARS-CoV-2 are reported to have increased risk for hospitalization, thrombosis, and other complications compared with non-sickle cell patients. …”
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106
Flavin Adenine Dinucleotide (FAD) and Pyridoxal 5′-Phosphate (PLP) Bind to Sox9 and Alter the Expression of Key Pancreatic Progenitor Transcription Factors
Published 2022“…Pyridoxal 5′-phosphate (PLP), the active form of vitamin B6, also binds to Sox9 and results in a similar increase in pancreatic development markers. …”
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107
Differential changes in cyclic adenosine 3′-5′ monophosphate (cAMP) effectors and major Ca2+ handling proteins during diabetic cardiomyopathy
Published 2023“…Early upregulation of Epac1 transcripts was noted in diabetic hearts at Week 4, followed by increases in Epac2 mRNA, but not protein levels, at Week 12. …”
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108
In-situ grown ternary metal hydroxides@3D oriented crumpled V₂C MXene sheets for improved electrocatalytic oxygen evolution reaction
Published 2024“…In essence, this study features a facile approach for the confined growth of multi transition metal hydroxides in the presence of morphologically unique 3D crumpled V₂C MXene architectures. Consequently, the increased OER reaction kinetics and improved stability of the synthesized composites are potentially due to synergistic interplay between well dispersed active sites and the conductive substrate.…”
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109
Elevated Adipsin and Reduced C5a Levels in the Maternal Serum and Follicular Fluid During Implantation Are Associated With Successful Pregnancy in Obese Women
Published 2022“…Higher numbers of top-quality embryos were associated with increased levels of C3, properdin, C1q, factors H and B, C4, and adipsin, but with reduced C2 and C5a levels (p ≤ 0.01).…”
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A 5-year trend in the use of sodium-glucose co-transporter 2 inhibitors and other oral antidiabetic drugs in a Middle Eastern country
Published 2022“…The trend among SGLT2is suggests greater preference for empagliflozin over dapagliflozin.…”
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Coevolving residues distant from the ligand binding site are involved in GAF domain function
Published 2025“…<p dir="ltr">Ligand binding to GAF domains regulates the activity of associated catalytic domains in various proteins, such as the cGMP-hydrolyzing catalytic domain of phosphodiesterase 5 (PDE5) activated by cGMP binding to GAFa domain. …”
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112
Exendin-4 promotes GSIS without increasing β-cell number through upregulation of glucose-sensing apparatus and mitochondrial oxidative phosphorylation machinery genes in hPSC-deriv...
Published 2023“…This consists of 6 stages: S1, definitive endoderm; S2, gut tube endoderm; S3, pancreatic progenitors 1; S4, pancreatic progenitors 2; S5, endocrine precursors; and S6, β-like cells. …”
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Lifetime prevalence, risk, and treatment of mood and anxiety disorders in Qatar's national mental health study
Published 2024“…Treatment contact in the year of disorder onset were 13.5%. The median delay in receiving treatment was 5 years (IQR = 2–13). …”
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115
Theoretical and experimental investigations of vanadium pentoxide–based electrocatalysts for the hydrogen evolution reaction in alkaline media
Published 2024“…This was reflected experimentally through kinetically non-ideal alkaline electrochemical HER using Zn<sub>0.4</sub>V<sub>1.6</sub>O<sub>5</sub> whereby − 194 mV of overpotential was required to attain − 10 mA/cm<sup>2</sup> of current density, as opposed to pristine V<sub>2</sub>O<sub>5</sub> which required 32% higher overpotential requirement at the same conditions. …”
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The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR)
Published 2023“…These results reiterate the decisive role of 5-Aza-CdR in lung cancer treatment since it induces the epigenetic regulation of NY-ESO-1 antigen, inhibits cell proliferation, increases apoptosis, and decreases invasiveness.…”
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117
Age, Disease Severity and Ethnicity Influence Humoral Responses in a Multi-Ethnic COVID-19 Cohort
Published 2021“…As expected, patients with severe disease showed significantly higher antibody titers and interestingly also had significantly broader epitope coverage. A significant increase in antibody titer and epitope coverage was observed with increasing age, in both mild and severe disease, which is promising for vaccine efficacy in older individuals. …”
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Deciphering the In vitro Role of microRNAs miR-21-3p and miR-222-5p In the Regulation of Clostridioides difficile Flagellin-Induced Inflammation
Published 2024“…Western blot and pathway analyses demonstrated that miR-222-5p and miR-21-3p overexpression increased phosphorylation of p65, a key component of the NF-κB complex, while their knockdown reduced p65 phosphorylation. …”
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masterThesis -
119
The Identification Process & Tools for Gifted and Talented Students: Research on Five inclusive government schools in Ajman to study the areas of identification process tools utili...
Published 2016“…With the increase focus on innovation and creativity, the Giftedness Education has become embedded with the UAE government’s future strategies. …”
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Role of Active Morphing in the Aerodynamic Performance of Flapping Wings in Formation Flight
Published 2021“…Migratory birds have the ability to save energy during flight by arranging themselves in a V-formation. This arrangement enables an increase in the overall efficiency of the group because the wake vortices shed by each of the birds provide additional lift and thrust to every member. …”
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